Single-Photon-Counting Performance of 4H-SiC Avalanche Photodiodes With a Wide-Range Incident Flux

2020 ◽  
Vol 32 (14) ◽  
pp. 847-850
Author(s):  
Xingye Zhou ◽  
Xin Tan ◽  
Yuanjie Lv ◽  
Yuangang Wang ◽  
Jia Li ◽  
...  
2021 ◽  
Author(s):  
Julia R. Lazzari-Dean ◽  
Evan W. Miller

AbstractBackgroundMembrane potential (Vmem) exerts physiological influence across a wide range of time and space scales. To study Vmem in these diverse contexts, it is essential to accurately record absolute values of Vmem, rather than solely relative measurements.Materials & MethodsWe use fluorescence lifetime imaging of a small molecule voltage sensitive dye (VF2.1.Cl) to estimate mV values of absolute membrane potential.ResultsWe test the consistency of VF2.1.Cl lifetime measurements performed on different single photon counting instruments and find that they are in striking agreement (differences of <0.5 ps/mV in the slope and <50 ps in the y-intercept). We also demonstrate that VF2.1.Cl lifetime reports absolute Vmem under two-photon (2P) illumination with better than 20 mV of Vmem resolution, a nearly 10-fold improvement over other lifetime-based methods.ConclusionsWe demonstrate that VF-FLIM is a robust and portable metric for Vmem across imaging platforms and under both one-photon and two-photon illumination. This work is a critical foundation for application of VF-FLIM to record absolute membrane potential signals in thick tissue.


2008 ◽  
Author(s):  
Ping Yuan ◽  
Joseph Boisvert ◽  
Rengarajan Sudharsanan ◽  
Takahiro Isshiki ◽  
Paul McDonald ◽  
...  

2021 ◽  
Author(s):  
Matteo Battisti ◽  
Enrico Arnone ◽  
Mario Bertaina ◽  
Marco Casolino ◽  
Laura Marcelli ◽  
...  

&lt;p&gt;Elves are the most common type of transient luminous events, with estimates of their global occurrence rate ranging from a few to a few tens per minute. Here, we present the first derivation of the global occurrence rate of elves from Mini-EUSO observations. Mini-EUSO is a wide field of view, space-based telescope operating from a nadir-facing UV-transparent window in the Russian Zvezda module on the International Space Station. It observes the Earth&amp;#8217;s atmosphere in the UV band with a spatial resolution of about 6.3 km and a temporal resolution of 2.5 &amp;#956;s. Its optical system made of two 25 cm diameter Fresnel lenses focuses the light into a square array of 48x48 pixels, each pixel being capable of single photon counting. Originally designed to detect the faint fluorescence light produced by extensive air showers induced by extreme energy cosmic rays, it was shown to be capable of detecting a wide range of atmospheric phenomena, including elves.&amp;#160;Elves are dynamically traced by Mini-EUSO in their horizontally expanding, fast donut-shaped light emissions and can therefore be unequivocally identified. Mini-EUSO can usually detect elves whose center is just outside the field of view, following the expansion of the ring for hundreds of microseconds. Combining the number of detected elves with consideration of the time and geometries, it is possible to derive a first estimate of their global occurrence rate with Mini-EUSO, and to compare it to the literature.&amp;#160;&lt;/p&gt;


2019 ◽  
Vol 40 (12) ◽  
pp. 121802 ◽  
Author(s):  
Linlin Su ◽  
Dong Zhou ◽  
Hai Lu ◽  
Rong Zhang ◽  
Youdou Zheng

2000 ◽  
Vol 39 (36) ◽  
pp. 6746 ◽  
Author(s):  
John G. Rarity ◽  
Thomas E. Wall ◽  
Kevin D. Ridley ◽  
Philippa C. M. Owens ◽  
Paul R. Tapster

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