Optimal Satellite Gateway Placement in Space-Ground Integrated Network for Latency Minimization With Reliability Guarantee

2018 ◽  
Vol 7 (2) ◽  
pp. 174-177 ◽  
Author(s):  
Yurui Cao ◽  
Yongpeng Shi ◽  
Jiajia Liu ◽  
Nei Kato
2010 ◽  
Vol 24 (3) ◽  
pp. 161-172 ◽  
Author(s):  
Edmund Wascher ◽  
C. Beste

Spatial selection of relevant information has been proposed to reflect an emergent feature of stimulus processing within an integrated network of perceptual areas. Stimulus-based and intention-based sources of information might converge in a common stage when spatial maps are generated. This approach appears to be inconsistent with the assumption of distinct mechanisms for stimulus-driven and top-down controlled attention. In two experiments, the common ground of stimulus-driven and intention-based attention was tested by means of event-related potentials (ERPs) in the human EEG. In both experiments, the processing of a single transient was compared to the selection of a physically comparable stimulus among distractors. While single transients evoked a spatially sensitive N1, the extraction of relevant information out of a more complex display was reflected in an N2pc. The high similarity of the spatial portion of these two components (Experiment 1), and the replication of this finding for the vertical axis (Experiment 2) indicate that these two ERP components might both reflect the spatial representation of relevant information as derived from the organization of perceptual maps, just at different points in time.


Author(s):  
Ning Zhao ◽  
Hao Wu ◽  
F. Richard Yu ◽  
Lifu Wang ◽  
Weiting Zhang ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sinead M. O’Donovan ◽  
Ali Imami ◽  
Hunter Eby ◽  
Nicholas D. Henkel ◽  
Justin Fortune Creeden ◽  
...  

AbstractThe COVID-19 pandemic caused by the novel SARS-CoV-2 is more contagious than other coronaviruses and has higher rates of mortality than influenza. Identification of effective therapeutics is a crucial tool to treat those infected with SARS-CoV-2 and limit the spread of this novel disease globally. We deployed a bioinformatics workflow to identify candidate drugs for the treatment of COVID-19. Using an “omics” repository, the Library of Integrated Network-Based Cellular Signatures (LINCS), we simultaneously probed transcriptomic signatures of putative COVID-19 drugs and publicly available SARS-CoV-2 infected cell lines to identify novel therapeutics. We identified a shortlist of 20 candidate drugs: 8 are already under trial for the treatment of COVID-19, the remaining 12 have antiviral properties and 6 have antiviral efficacy against coronaviruses specifically, in vitro. All candidate drugs are either FDA approved or are under investigation. Our candidate drug findings are discordant with (i.e., reverse) SARS-CoV-2 transcriptome signatures generated in vitro, and a subset are also identified in transcriptome signatures generated from COVID-19 patient samples, like the MEK inhibitor selumetinib. Overall, our findings provide additional support for drugs that are already being explored as therapeutic agents for the treatment of COVID-19 and identify promising novel targets that are worthy of further investigation.


2021 ◽  
Vol 13 (5) ◽  
pp. 128
Author(s):  
Jun Liu ◽  
Xiaohui Lian ◽  
Chang Liu

In Space–Air–Ground Integrated Networks (SAGIN), computation offloading technology is a new way to improve the processing efficiency of node tasks and improve the limitation of computing storage resources. To solve the problem of large delay and energy consumption cost of task computation offloading, which caused by the complex and variable network offloading environment and a large amount of offloading tasks, a computation offloading decision scheme based on Markov and Deep Q Networks (DQN) is proposed. First, we select the optimal offloading network based on the characteristics of the movement of the task offloading process in the network. Then, the task offloading process is transformed into a Markov state transition process to build a model of the computational offloading decision process. Finally, the delay and energy consumption weights are introduced into the DQN algorithm to update the computation offloading decision process, and the optimal offloading decision under the low cost is achieved according to the task attributes. The simulation results show that compared with the traditional Lyapunov-based offloading decision scheme and the classical Q-learning algorithm, the delay and energy consumption are respectively reduced by 68.33% and 11.21%, under equal weights when the offloading task volume exceeds 500 Mbit. Moreover, compared with offloading to edge nodes or backbone nodes of the network alone, the proposed mixed offloading model can satisfy more than 100 task requests with low energy consumption and low delay. It can be seen that the computation offloading decision proposed in this paper can effectively reduce the delay and energy consumption during the task computation offloading in the Space–Air–Ground Integrated Network environment, and can select the optimal offloading sites to execute the tasks according to the characteristics of the task itself.


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