High Resolution, High Sensitivity Detectors for Functional Molecular Imaging with Radionuclides: the Role of Scintillator Pixel Size, Photodetector Anode Dimension, Collimation Technique and Readout

2006 ◽  
Author(s):  
F. Garibaldi ◽  
R. Accorsi ◽  
M.N. Cinti ◽  
E. Cisbani ◽  
S. Colilli ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
High Resolution ◽  
High Sensitivity ◽  
Pixel Size

scholarly journals Magnetic fields in irregular galaxies

2008 ◽  
Vol 4 (S259) ◽  
pp. 555-556
Author(s):  
Amanda Kepley ◽  
Eric Wilcots ◽  
Ellen Zweibel ◽  
Stefanie Mühle ◽  
John Everett ◽  
...  
Keyword(s):  
High Resolution ◽  
Magnetic Fields ◽  
Interstellar Medium ◽  
High Sensitivity ◽  
Irregular Galaxies ◽  
Ngc 1569

AbstractThe low masses of irregular galaxies change the behavior of their interstellar medium (ISM) compared to that of normal spirals, so the role of magnetic fields in the ISM in irregulars may be very different than in spirals. We present high-resolution and high-sensitivity observations of the magnetic fields of two irregular galaxies: NGC 4214 and NGC 1569.

Development of Positron Emission Tomography With Wobbling and Zooming for High Sensitivity and High-Resolution Molecular Imaging

2019 ◽  
Vol 38 (12) ◽  
pp. 2875-2882 ◽  
Author(s):  
Zang-Hee Cho ◽  
Young-Don Son ◽  
Hang-Keun Kim ◽  
Dae-Hyuk Kwon ◽  
Yo-Han Joo ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Molecular Imaging ◽  
High Resolution ◽  
High Sensitivity ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Front-Inner Lens for High Sensitivity of CMOS Image Sensors

Sensors ◽  
2019 ◽  
Vol 19 (7) ◽  
pp. 1536 ◽  
Author(s):  
Godeun Seok ◽  
Yunkyung Kim
Keyword(s):  
High Resolution ◽  
Aspect Ratio ◽  
High Sensitivity ◽  
Image Sensor ◽  
Image Sensors ◽  
Optical Simulation ◽  
Optical Performance ◽  
Pixel Size ◽  
Cmos Image Sensors ◽  
Pixel Pitch

Due to the continuing improvements in camera technology, a high-resolution CMOS image sensor is required. However, a high-resolution camera requires that the pixel pitch is smaller than 1.0 μm in the limited sensor area. Accordingly, the optical performance of the pixel deteriorates with the aspect ratio. If the pixel depth is shallow, the aspect ratio is enhanced. Also, optical performance can improve if the sensitivity in the long wavelengths is guaranteed. In this current work, we propose a front-inner lens structure that enhances the sensitivity to the small pixel size and the shallow pixel depth. The front-inner lens was located on the front side of the backside illuminated pixel for enhancement of the absorption. The proposed structures in the 1.0 μm pixel pitch were investigated with 3D optical simulation. The pixel depths were 3.0, 2.0, and 1.0 μm. The materials of the front-inner lens were varied, including air and magnesium fluoride (MgF2). For analysis of the sensitivity enhancement, we compared the typical pixel with the suggested pixel and confirmed that the absorption rate of the suggested pixel was improved by a maximum of 7.27%, 10.47%, and 29.28% for 3.0, 2.0, and 1.0 μm pixel depths, respectively.

Backscattered Electron Imaging of GaAs/AlGaAs Super Lattice Structures with an Ultra-High- Resolution SEM

1988 ◽  
Vol 46 ◽  
pp. 204-205
Author(s):  
Kazumichi Ogura ◽  
Michael M. Kersker
Keyword(s):  
High Resolution ◽  
Layer Structure ◽  
High Sensitivity ◽  
Beam Current ◽  
Electron Beam Current ◽  
Lattice Structures ◽  
Super Lattice ◽  
Different Types ◽  
Backscattered Electron ◽  
Electron Imaging

Backscattered electron (BE) images of GaAs/AlGaAs super lattice structures were observed with an ultra high resolution (UHR) SEM JSM-890 with an ultra high sensitivity BE detector. Three different types of super lattice structures of GaAs/AlGaAs were examined. Each GaAs/AlGaAs wafer was cleaved by a razor after it was heated for approximately 1 minute and its crosssectional plane was observed.First, a multi-layer structure of GaAs (100nm)/AlGaAs (lOOnm) where A1 content was successively changed from 0.4 to 0.03 was observed. Figures 1 (a) and (b) are BE images taken at an accelerating voltage of 15kV with an electron beam current of 20pA. Figure 1 (c) is a sketch of this multi-layer structure corresponding to the BE images. The various layers are clearly observed. The differences in A1 content between A1 0.35 Ga 0.65 As, A1 0.4 Ga 0.6 As, and A1 0.31 Ga 0.69 As were clearly observed in the contrast of the BE image.

Quantitative accuracy of serotonergic neurotrans-mission imaging with high-resolution 123I SPECT

2004 ◽  
Vol 43 (06) ◽  
pp. 185-189 ◽  
Author(s):  
J. T. Kuikka
Keyword(s):  
High Resolution ◽  
Scatter Correction ◽  
Region Of Interest ◽  
Binding Potential ◽  
Partial Volume ◽  
Therapeutic Drugs ◽  
Quantitative Accuracy ◽  
Critical Error ◽  
Statistical Noise

Summary Aim: Serotonin transporter (SERT) imaging can be used to study the role of regional abnormalities of neurotransmitter release in various mental disorders and to study the mechanism of action of therapeutic drugs or drugs’ abuse. We examine the quantitative accuracy and reproducibility that can be achieved with high-resolution SPECT of serotonergic neurotransmission. Method: Binding potential (BP) of 123I labeled tracer specific for midbrain SERT was assessed in 20 healthy persons. The effects of scatter, attenuation, partial volume, mis-registration and statistical noise were estimated using phantom and human studies. Results: Without any correction, BP was underestimated by 73%. The partial volume error was the major component in this underestimation whereas the most critical error for the reproducibility was misplacement of region of interest (ROI). Conclusion: The proper ROI registration, the use of the multiple head gamma camera with transmission based scatter correction introduce more relevant results. However, due to the small dimensions of the midbrain SERT structures and poor spatial resolution of SPECT, the improvement without the partial volume correction is not great enough to restore the estimate of BP to that of the true one.

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