Tinea corporis caused by terbinafine‐resistant Trichophyton rubrum successfully treated with fosravuconazole

Author(s):  
Yurie Kitauchi ◽  
Yoshiko Kumagai ◽  
Yoko Inoue‐Masuda ◽  
Makoto Sugiura ◽  
Tomotaka Sato ◽  
...  
2011 ◽  
Vol 173 (2-3) ◽  
pp. 135-138 ◽  
Author(s):  
E. T. M. Mapelli ◽  
E. Borghi ◽  
A. Cerri ◽  
R. Sciota ◽  
G. Morace ◽  
...  

2014 ◽  
Vol 179 (3-4) ◽  
pp. 293-297 ◽  
Author(s):  
Q. T. Kong ◽  
X. Du ◽  
R. Yang ◽  
S. Y. Huang ◽  
H. Sang ◽  
...  

2021 ◽  
Vol 12 (4) ◽  
pp. 374-380
Author(s):  
Rabiya Bashir ◽  
Naina Kala Dogra ◽  
Bella Mahajan

Background: Chronic dermatophytosis is a considerable challenge in routine clinical practice. There is, however, scarce information available in the literature on its extent and characteristics. Aim: The aim of this study was to evaluate the host-related factors of chronic dermatophytosis and to identify the common fungal isolates. Methods: The study enrolled a total of 145 cases of chronic dermatophytosis attending the out-patient department of a tertiary care hospital in Jammu from November 2017 through October 2018. A detailed history was taken, followed by a clinical examination and investigations such as routine baseline investigations, an absolute eosinophil count, a wet mount for direct microscopy, and a fungal culture. Results: The most common presentation was tinea corporis with tinea cruris (33.1%), followed by tinea corporis alone. The majority of the patients (54.5%) had more than 20% of the body surface area involved. Most of the patients were manual workers (n = 44; 30.3%). The number of hours of sun exposure varied between 1 to 8.5 hours (mean ± SD: 3.53 ± 1.75 h). The fungal culture was positive in 65 (44.8%) patients. The most frequent isolates were Trichophyton mentagrophytes (53.8%), followed by Trichophyton rubrum (38.5%). Conclusion: We found Trichophyton mentagrophytes the predominant pathogen in chronic dermatophytosis, followed by Trichophyton rubrum, which demonstrates a changing trend as far as the causative organism is considered. Besides, various risk factors for chronicity such as prolonged sun exposure, lack of proper hygiene, wearing tight-fitting synthetic clothes, the use of topical steroids, and non-compliance to treatment were identified.


2013 ◽  
Vol 88 (4) ◽  
pp. 627-630 ◽  
Author(s):  
Camila Fernanda Novak Pinheiro de Freitas ◽  
Fabiane Mulinari-Brenner ◽  
Hanae Rafaela Fontana ◽  
Arthur Conelian Gentili ◽  
Mariana Hammerschmidt

Ichthyoses are a common group of keratinization disorders. A non-inflammatory generalized persistent skin desquamation is observed. It is characterized by increased cell turnover, thickening of the stratum corneum and functional changes of sebaceous and sweat glands. All of these favor fungal proliferation. Dermatophytes may infect skin, hair and nails causing ringworm or tinea. They have the ability to obtain nutrients from keratinized material. One of its most prevalent genera is Trichophyton rubrum. Although tineas and ichthyoses are quite common, the association of the two entities is rarely reported in the literature. Three cases of ichthyosis associated with widespread infection by T. rubrum are presented. Resistance to several antifungal treatments was responsible for worsening of ichthyosis signs and symptoms.


2017 ◽  
Vol 1 (3) ◽  
pp. 165-168
Author(s):  
Lizy M Paniagua Gonzalez ◽  
Alison Lowe ◽  
Michael Wilkerson

Worldwide, Trichophyton rubrum is the most common cause of dermatophytosis. Infection is classically superficial, limited to the cornified layers of the skin, and may be accompanied by varying degrees of inflammation. Dermatophyte invasion is limited by multiple host factors, including sebum production, an intact skin barrier, and immunocompetence. We describe a 65 year old gentleman with a history of diabetes mellitus, hypertension, nephrogenic systemic fibrosis, and immunosuppressed status due to renal transplant who presented with a non-healing ulcer of the left dorsal hand. Further examination revealed palmar erythema and scale as well as annular erythematous plaques with peripheral scale on his bilateral knees. Laboratory testing yielded the diagnosis of tinea corporis, with bacterial superinfection of the left dorsal hand. The patient was started on systemic antimicrobials with complete healing of the ulcer along with total clearance of the rash. This case highlights an unusual presentation of invasive Trichophyton rubrum in the setting of immunosuppression and nephrogenic systemic fibrosis.


1986 ◽  
Vol 15 (4) ◽  
pp. 710-712 ◽  
Author(s):  
Michael Kahana ◽  
Miriam Schewach-Millet ◽  
Lea Shalish

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