Effect of pretreatment with intracerebroventricular injection of minocycline on morphine‐induced memory impairment in passive avoidance test: Role of P‐ CREB and c‐Fos expression in the dorsal hippocampus and basolateral amygdala regions

2019 ◽  
Vol 46 (8) ◽  
pp. 711-722 ◽  
Author(s):  
Shokouh Hamidkhaniha ◽  
Hamideh Bashiri ◽  
Ameneh Omidi ◽  
Ali Hosseini‐Chegeni ◽  
Seyed Mohammad Tavangar ◽  
...  
Keyword(s):  
Passive Avoidance ◽  
Memory Impairment ◽  
Basolateral Amygdala ◽  
Dorsal Hippocampus ◽  
Passive Avoidance Test ◽  
Intracerebroventricular Injection ◽  
Avoidance Test ◽  
Fos Expression

Investigation of the Memory Impairment in Rats Fed with Oxidized-Cholesterol-Rich Diet Employing Passive Avoidance Test

Drug Research ◽  
2014 ◽  
Vol 65 (05) ◽  
pp. 231-237 ◽  
Author(s):  
A. Khorrami ◽  
S. Ghanbarzadeh ◽  
J. Mahmoudi ◽  
A. Nayebi ◽  
N. Maleki-Dizaji ◽  
...  
Keyword(s):  
Passive Avoidance ◽  
Memory Impairment ◽  
Passive Avoidance Test ◽  
Avoidance Test ◽  
Oxidized Cholesterol

scholarly journals Butea superba Roxb. Extract Ameliorates Scopolamine-Induced Cognitive and Memory Impairment in Aged Male Rats

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Kittipot Sirichaiwetchakoon ◽  
Sarawut Suksuphew ◽  
Rungrudee Srisawat ◽  
Griangsak Eumkeb
Keyword(s):  
Passive Avoidance ◽  
Memory Impairment ◽  
Neurodegenerative Disorder ◽  
Ex Vivo ◽  
Radical Scavenging ◽  
Male Rats ◽  
Passive Avoidance Test ◽  
Dependent Manner ◽  
Avoidance Test ◽  
Butea Superba

Butea superba Roxb. (B. superba) is a herb that has been used for rejuvenation, to improve sexual performance, or to prevent erectile dysfunction function. Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that is the main cause of progressive dementia. This study aimed to investigate the amelioration for cognitive and memory dysfunction of B. superba ethanolic extract (BSE), a possible mechanism of action, and its toxicity. The results from the Y-maze test, novel object recognition test, and passive avoidance test exhibited that the administration of BSE at 50 mg/kg (BSL) and 200 mg/kg (BSH) could ameliorate scopolamine-induced cognitive impairment in all behavior testing. Moreover, BSE could prevent the cognitive deficit in a dose-dependent manner in a passive avoidance test. Furthermore, BSE inhibited acetylcholinesterase’s (AChE) ex vivo activity in the cerebral cortex and hippocampus. Also, the in vitro and ex vivo antioxidative effects of BSE revealed that BSE had free radical scavenging activities in both DPPH and FRAP assay. Furthermore, male rats treated with BSE at 200 mg/kg/day for two weeks could significantly increase serum testosterone compared with control ( P < 0.05 ). The GC-MS analysis and previous studies revealed that BSE contained propanoic acid, 3,3′-thiobis-, didodecyl ester, oleic acid, gamma-sitosterol, and stigmasterol which may play an important role in cognitive and memory impairment prevention. The toxicity test of BSE in rats at 50 and 200 mg/kg/day for two weeks showed that relative organ weight, serum creatinine, ALT, ALP, and CBC levels of both treated groups were not significantly different compared to the CON ( P > 0.05 ). These results suggest that BSE may not be toxic to the vital organ and blood. In conclusion, BSE has the potential to be developed as a health supplement product or medicine for AD prevention and treatment.

Vasopressin analogues with effect on central nervous system: Synthesis and biological properties

1983 ◽  
Vol 48 (10) ◽  
pp. 2862-2873 ◽  
Author(s):  
František Brtník ◽  
Ivan Krejčí ◽  
Běla Kupková ◽  
Pavel Hrbas ◽  
Jana Škopková ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Amino Acid ◽  
Passive Avoidance ◽  
Biological Properties ◽  
Passive Avoidance Test ◽  
System Synthesis ◽  
Avoidance Test ◽  
Vasopressin Analogues

Synthesis of four vasopressin analogues which do not contain the glycinamine residue in position 9 and have a basic non-coded amino acid in position 8 is described. All the analogues exhibit very low endocrine activities and are effective in the passive avoidance test.

Effects of Clozapine and Sulpiride on Morphine State-Dependent Memory in the Step-Down Passive Avoidance Test

Pharmacology ◽  
2006 ◽  
Vol 79 (3) ◽  
pp. 149-153 ◽  
Author(s):  
Nazanin Malekmohamadi ◽  
Parviz Heidari ◽  
Mousa Sahebgharani ◽  
Mohammad-Reza Zarrindast
Keyword(s):  
Passive Avoidance ◽  
Passive Avoidance Test ◽  
Avoidance Test ◽  
State Dependent ◽  
Step Down

Continuous and not continuous 2-week treadmill training enhances the performance in the passive avoidance test in ischemic gerbils

2018 ◽  
Vol 665 ◽  
pp. 170-175 ◽  
Author(s):  
Ana Paula Cassiano Silveira ◽  
Takae Tamy Kitabatake ◽  
Vivian Mozol Pantaleo ◽  
Hélio Zangrossi ◽  
Guilherme Bertolino ◽  
...  
Keyword(s):  
Passive Avoidance ◽  
Treadmill Training ◽  
Passive Avoidance Test ◽  
Avoidance Test

scholarly journals Antiamnesic effect of the two novel ?-opioid agonists, VA-100 and VA-101, in the mouse passive avoidance test

2001 ◽  
Vol 54 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Carla Ghelardini ◽  
Nicoletta Galeotti ◽  
Lorenzo Di Cesare Mannelli ◽  
Andrea Cappelli ◽  
Maurizio Anzini ◽  
...  
Keyword(s):  
Passive Avoidance ◽  
Passive Avoidance Test ◽  
Avoidance Test ◽  
Opioid Agonists
Sign in / Sign up

Export Citation Format

Share Document