Disentangling the impact of alcohol use and hepatitis C on insulin action in Latino individuals

Author(s):  
Rebecca G Kim ◽  
Jonathan Kramer‐Feldman ◽  
Peter Bacchetti ◽  
Barbara Grimes ◽  
Esteban Burchard ◽  
...  
1998 ◽  
Vol 28 (6) ◽  
pp. 945-950 ◽  
Author(s):  
Stanislas Pol ◽  
Barbara Lamorthe ◽  
Ngoc Trinh Thi ◽  
Valérie Thiers ◽  
Françoise Carnot ◽  
...  

Hepatology ◽  
2012 ◽  
Vol 56 (4) ◽  
pp. 1223-1230 ◽  
Author(s):  
Marcia Russell ◽  
Mary Patricia Pauly ◽  
Charles Denton Moore ◽  
Constance Chia ◽  
Jennifer Dorrell ◽  
...  

2005 ◽  
Vol 22 (8) ◽  
pp. 701-706 ◽  
Author(s):  
A. CHANG ◽  
K. SKOLE ◽  
M. GAUTAM ◽  
J. SCHMUTZ ◽  
M. BLACK ◽  
...  

Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 716
Author(s):  
Daniel Fuster ◽  
David Nunes ◽  
Debbie M. Cheng ◽  
Richard Saitz ◽  
Jeffrey H. Samet

Background: The impact of Hepatitis C virus (HCV) RNA levels on the evolution of chronic HCV infection-related liver damage is controversial. Heavy alcohol use is believed to have a deleterious impact on the course of HCV disease, but current knowledge about the possible effect of alcohol use on HCV RNA levels in HIV/HCV coinfected patients is limited. Methods: We examined 107 HIV/HCV-infected individuals with current or past unhealthy alcohol use to assess the association between alcohol consumption (any drinking vs. abstinent) and HCV RNA levels. Results: Participants were 75% male, with a mean age of 43 years, and 63% were on antiretroviral therapy. Mean (SD) log HIV RNA was 3.1 (1.4) and mean (SD) log HCV RNA was 6.1 (0.8). Past-month alcohol use was present in 38% of participants. In a multivariable linear regression analysis we found no significant differences in mean log HCV RNA levels between those reporting alcohol use and those who were abstinent [β (95%CI): −0.04 (−0.34, 0.26), p = 0.79)]. There was no significant association between any heavy drinking day and HCV RNA level (0.07, 95% CI: (−0.24, 0.38), p = 0.66). Conclusions: We did not detect significant associations between alcohol use and HCV RNA levels among HIV/HCV coinfected patients.


2016 ◽  
Vol 61 (8) ◽  
pp. 2417-2425 ◽  
Author(s):  
Blaire E. Burman ◽  
Peter Bacchetti ◽  
Mandana Khalili

2005 ◽  
Vol 42 (5) ◽  
pp. 639-645 ◽  
Author(s):  
María Buti ◽  
Ramón San Miguel ◽  
Max Brosa ◽  
Juan M. Cabasés ◽  
Montserrat Medina ◽  
...  

Author(s):  
Emina Mehanović ◽  
Federica Vigna-Taglianti ◽  
Fabrizio Faggiano ◽  
Maria Rosaria Galanti ◽  
Barbara Zunino ◽  
...  

Abstract Purpose Adolescents’ perceptions of parental norms may influence their substance use. The relationship between parental norms toward cigarette and alcohol use, and the use of illicit substances among their adolescent children is not sufficiently investigated. The purpose of this study was to analyze this relationship, including gender differences, using longitudinal data from a large population-based study. Methods The present study analyzed longitudinal data from 3171 12- to 14-year-old students in 7 European countries allocated to the control arm of the European Drug Addiction Prevention trial. The impact of parental permissiveness toward cigarettes and alcohol use reported by the students at baseline on illicit drug use at 6-month follow-up was analyzed through multilevel logistic regression models, stratified by gender. Whether adolescents’ own use of cigarette and alcohol mediated the association between parental norms and illicit drug use was tested through mediation models. Results Parental permissive norms toward cigarette smoking and alcohol use at baseline predicted adolescents’ illicit drug use at follow-up. The association was stronger among boys than among girls and was mediated by adolescents’ own cigarette and alcohol use. Conclusion Perceived parental permissiveness toward the use of legal drugs predicted adolescents’ use of illicit drugs, especially among boys. Parents should be made aware of the importance of norm setting, and supported in conveying clear messages of disapproval of all substances.


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