Early life temperamental anxiety is associated with excessive alcohol intake in adolescence: A rhesus monkey ( Macaca mulatta ) model

2019 ◽  
Vol 25 (6) ◽  
Author(s):  
Elizabeth K. Wood ◽  
Ryno Kruger ◽  
Elysha Cash ◽  
Stephen G. Lindell ◽  
Melanie L. Schwandt ◽  
...  
Keyword(s):  
Rhesus Monkey ◽  
Macaca Mulatta ◽  
Early Life ◽  
Alcohol Intake ◽  
Excessive Alcohol ◽  
Excessive Alcohol Intake

1054 MODERATE AND EXCESSIVE ALCOHOL INTAKE IMPACT TRANSPLANT-FREE SURVIVAL: A LONGITUDINAL STUDY IN HCV CIRRHOTIC PATIENTS

2010 ◽  
Vol 52 ◽  
pp. S408
Author(s):  
P. Deltenre ◽  
M. El Nady ◽  
M. Corouge ◽  
V. Canva ◽  
A. Louvet ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Alcohol Intake ◽  
Free Survival ◽  
Excessive Alcohol ◽  
Cirrhotic Patients ◽  
Excessive Alcohol Intake

scholarly journals Acute Kidney Injury by Renal Hemosiderosis Secondary to Primary Cold Agglutinin Disease Associated with an Excessive Alcohol Intake

2018 ◽  
Vol 57 (22) ◽  
pp. 3261-3265
Author(s):  
Aya Imafuku ◽  
Go Yamamoto ◽  
Koji Takemura ◽  
Eiko Hasegawa ◽  
Naoki Sawa ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Alcohol Intake ◽  
Kidney Injury ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease ◽  
Excessive Alcohol ◽  
Excessive Alcohol Intake

scholarly journals The effects of obesity, smoking, and excessive alcohol intake on healthcare expenditure in a comprehensive medical scheme

2013 ◽  
Vol 103 (11) ◽  
pp. 840 ◽  
Author(s):  
R Sturm ◽  
R An ◽  
J Maroba ◽  
D Patel
Keyword(s):  
Alcohol Intake ◽  
Healthcare Expenditure ◽  
Excessive Alcohol ◽  
Excessive Alcohol Intake

scholarly journals Inflammation in Primary and Metastatic Liver Tumorigenesis–Under the Influence of Alcohol and High-Fat Diets

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 933 ◽  
Author(s):  
Lauren S. Strathearn ◽  
Afanasii I. Stepanov ◽  
Joan Font-Burgada
Keyword(s):  
Liver Disease ◽  
Liver Metastasis ◽  
Alcohol Intake ◽  
Cancer Type ◽  
High Fat ◽  
High Fat Diets ◽  
Excessive Alcohol ◽  
Fat Diets ◽  
Metastatic Liver ◽  
Excessive Alcohol Intake

The liver plays an outsized role in oncology. Liver tumors are one of the most frequently found tumors in cancer patients and these arise from either primary or metastatic disease. Hepatocellular carcinoma (HCC), the most prevalent form of primary liver cancer and the 6th most common cancer type overall, is expected to become the 3rd leading cause of cancer mortality in the US by the year 2030. The liver is also the most common site of distant metastasis from solid tumors. For instance, colorectal cancer (CRC) metastasizes to the liver in two-thirds of cases, and CRC liver metastasis is the leading cause of mortality in these patients. The interplay between inflammation and cancer is unmistakably evident in the liver. In nearly every case, HCC is diagnosed in chronic liver disease (CLD) and cirrhosis background. The consumption of a Western-style high-fat diet is a major risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), both of which are becoming more prevalent in parallel with the obesity epidemic. Excessive alcohol intake also contributes significantly to the CLD burden in the form of alcoholic liver disease (ALD). Inflammation is a key component in the development of all CLDs. Additionally, during the development of liver metastasis, pro-inflammatory signaling is crucial in eliminating invading cancer cells but ironically also helps foster a pro-metastatic environment that supports metastatic seeding and colonization. Here we review how Westernized high-fat diets and excessive alcohol intake can influence inflammation within the liver microenvironment, stimulating both primary and metastatic liver tumorigenesis.

scholarly journals Excessive Alcohol Intake Increases the Risk of Arterial Stiffening in Men with Normal Blood Pressure

2004 ◽  
Vol 27 (9) ◽  
pp. 669-673 ◽  
Author(s):  
Takashi KURIHARA ◽  
Hirofumi TOMIYAMA ◽  
Hideki HASHIMOTO ◽  
Yoshio YAMAMOTO ◽  
Eiji YANO ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Alcohol Intake ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Arterial Stiffening ◽  
Excessive Alcohol ◽  
Excessive Alcohol Intake

Chlormethiazole Abuse

1979 ◽  
Vol 134 (6) ◽  
pp. 627-629 ◽  
Author(s):  
Elizabeth Gregg ◽  
Iftikhar Akhter
Keyword(s):  
Alcohol Intake ◽  
Drug Seeking ◽  
Excessive Alcohol ◽  
Symptoms And Signs ◽  
Excessive Alcohol Intake

SummaryThis report describes 17 cases of chlormethiazole abuse or dependence. These include one case with symptoms and signs of withdrawal and two other similar cases where undoubted dependence was combined with excessive alcohol intake. Seven other patients with alcoholism who indulged in drug-seeking behaviour involving chlormethiazole are also reported, together with a further seven abusers of various other drugs who were also discovered to be taking chlormethiazole.

scholarly journals The effects of smoking and alcoholism in acute coronary syndrome

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
J Correia ◽  
V Neto ◽  
J Santos ◽  
I Pires ◽  
L Goncalves ◽  
...  
Keyword(s):  
Hospital Mortality ◽  
Alcohol Intake ◽  
Mortality Rates ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
Group A ◽  
Excessive Alcohol ◽  
Group B ◽  
Group D ◽  
Excessive Alcohol Intake

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Several studies have concluded that smoking increases mortality in patients with coronary disease. On the other hand, a J-shaped dose-effect curve has been used to describe the relationship between alcohol and cardiovascular mortality. According to the majority of studies, a moderate intake of alcohol is associated with a decrease in mortality, while an excessive alcohol intake appears to increase mortality. Aim To evaluate the effect of smoking and excessive alcohol intake in hospital mortality and 1-year mortality in patients hospitalized due to acute coronary syndrome (ACS). Methods A single-centre retrospective study was conducted, with inclusion of all consecutive patients admitted in the Cardiology Department due to ACS. Follow-up started after hospital admission and ended upon hospital death, death within the following 12 months or 12 months after study entry. Patients were divided in two groups: smokers (Group-A) and non-smokers (Group-B), to analyse the effect of smoking in hospital mortality and 1-year mortality. To analyse the effect of excessive alcohol intake, patients were also divided in other two groups: Group-C (excessive drinkers) and Group-D (non-excessive drinkers). Statistical analysis was performed with SPSS and a p value < 0.05 was considered statistically significant. Results 1120 patients (68.9% male, mean age 69.12 ± 12.67 years) were included in this study. 20.5% were smokers and 3.2% had a previous excessive alcohol intake. Between Group-A and Group-B, a statistically significant difference was observed in gender (93.1% male in Group-A vs 62.9% male in Group-B, p = 0.002), but not in age (p = 0.116). Hospital mortality rates in Group-A and Group-B were respectively 6.0% and 8.7% (p = 0.191) and 1-year mortality rates were 3.1% vs 5.1% (p = 0.239). Between Group-C and Group-D, a statistically significant difference was observed in gender (94.4% male in Group-C vs 69.8% male in Group-B, p < 0.001), but not in age (p = 0.730). Hospital mortality rates in Group-C and Group-D were respectively 25% and 9.6% (p = 0.003) and 1-year mortality were 3.8% vs 6.6% (p = 0.577). Conclusions Smoking did not have a positive or negative effect in hospital mortality and 1-year mortality. However, excessive alcohol intake was associated with increased hospital mortality in this population.

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