FGF2 is an endogenous regulator of alcohol reward and consumption

2021 ◽  
Author(s):  
Oren Even‐Chen ◽  
Leonie Herburg ◽  
Ekaterini Kefalakes ◽  
Nataly Urshansky ◽  
Claudia Grothe ◽  
...  
Keyword(s):  
Endogenous Regulator

scholarly journals Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans

2014 ◽  
Vol 20 (16) ◽  
pp. 2621-2630 ◽  
Author(s):  
Bedoor Qabazard ◽  
Ling Li ◽  
Jan Gruber ◽  
Meng Teng Peh ◽  
Li Fang Ng ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Caenorhabditis Elegans ◽  
Endogenous Regulator

Adenosine as an Endogenous Regulator of Central Excitability

Emotions ◽  
2015 ◽  
pp. 429-440
Author(s):  
J. W. Phillis ◽  
R. A. Barraco ◽  
R. E. Delong
Keyword(s):  
Endogenous Regulator ◽  
Central Excitability

Prolactin releasing peptide (PrRP): An endogenous regulator of cell growth

Peptides ◽  
2006 ◽  
Vol 27 (5) ◽  
pp. 1099-1103 ◽  
Author(s):  
Willis K. Samson ◽  
Meghan M. Taylor
Keyword(s):  
Cell Growth ◽  
Endogenous Regulator ◽  
Prolactin Releasing Peptide

Role of adenosine as an endogenous regulator of respiration in hamster brown adipocytes

1984 ◽  
Vol 246 (3) ◽  
pp. C301-C307 ◽  
Author(s):  
R. J. Schimmel ◽  
L. McCarthy
Keyword(s):  
Adenylate Cyclase ◽  
Adenosine Deaminase ◽  
Inhibitory Effect ◽  
Dependent Manner ◽  
Brown Adipocytes ◽  
Adenosine Receptor Antagonist ◽  
Endogenous Regulator ◽  
Camp Generation ◽  
Adenosine Analogue

The action of endogeneous adenosine on isolated hamster brown adipocytes was examined. Adenosine production from brown adipocytes was measured after labeling of the intracellular nucleotide pool with [3H]adenine. Accumulation of [3H]adenosine in the incubation medium was maximum after 5 min of incubation and was still present after 20 min. When adenosine accumulation was prevented by addition of adenosine deaminase, the stimulatory effects of isoproterenol on oxygen uptake, lipolysis, and adenosine 3',5'-cyclic monophosphate (cAMP) generation were enhanced. However, basal rates of lipolysis and oxygen consumption and levels of cAMP were not affected on addition of adenosine deaminase. A similar potentiation of isoproterenol responses was produced by the adenosine receptor antagonist, 3-isobutyl-1-methylxanthine, present at a concentration (10 microM) which did not change basal levels of respiration or lipolysis. Addition of the adenosine analogue 2-chloroadenosine antagonized isoproterenol-stimulated respiration and lipolysis and prevented potentiation of isoproterenol responses with 3-isobutyl-1-methylxanthine. To localize the site of adenosine action, activity of adenylate cyclase in membrane preparations from brown adipocytes was measured. Isoproterenol-stimulated adenylate cyclase activity was partially inhibited by 2-chloroadenosine in a GTP-dependent manner. Addition of Na+ enhanced the inhibitory effect of 2-chloroadenosine, and 3-isobutyl-1-methylxanthine blocked it. The calculated 50% effective dose for 2-chloroadenosine inhibition was between 10 and 15 nM. These data suggest that adenosine produced by brown adipocytes is an endogenous regulator of respiration in these cells acting at the level of the adenylate cyclase enzyme.

scholarly journals Non‐neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5‐positive stem cells in mice

FEBS Journal ◽  
2014 ◽  
Vol 281 (20) ◽  
pp. 4672-4690 ◽  
Author(s):  
Toshio Takahashi ◽  
Hiroe Ohnishi ◽  
Yuki Sugiura ◽  
Kurara Honda ◽  
Makoto Suematsu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Endogenous Regulator ◽  
Proliferation And Differentiation

Intestinal alkaline phosphatase is an endogenous regulator of host microbiota

2013 ◽  
Vol 217 (3) ◽  
pp. S14
Author(s):  
Omeed Moaven ◽  
Konstantinos P. Economopoulos ◽  
Sayeda N. Alam ◽  
Nur Muhammad ◽  
Kanakaraju Kaliannan ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Intestinal Alkaline Phosphatase ◽  
Endogenous Regulator

scholarly journals Parathyroid-Hormone-Related Protein is a Neuroprotective Endogenous Regulator of L-Type Calcium Channels

2006 ◽  
Vol 6 ◽  
pp. 42-42
Author(s):  
O. Chatterjee ◽  
I. A. Nakchbandi ◽  
W. M. Philbrick ◽  
L. K. Kaczmarek ◽  
M. L. Brines ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Calcium Channels ◽  
Related Protein ◽  
Endogenous Regulator ◽  
Parathyroid Hormone Related Protein

The extraction, isolation and purification of an endogenous regulator for the 5-HT2 receptor

2011 ◽  
Vol 64 (4) ◽  
pp. 312-313 ◽  
Author(s):  
José A. Apud
Keyword(s):  
Isolation And Purification ◽  
Endogenous Regulator
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