Genetic variation in leptin and leptin receptor genes as a risk factor for idiopathic male infertility

Andrology ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 70-74 ◽  
Author(s):  
A. Hodžić ◽  
M. Ristanović ◽  
B. Zorn ◽  
C. Tulić ◽  
A. Maver ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Risk Factor ◽  
Male Infertility ◽  
Leptin Receptor ◽  
Idiopathic Male Infertility

scholarly journals Genetic variation in leptin and leptin receptor genes is a risk factor for idiopathic recurrent spontaneous abortion

2016 ◽  
Vol 57 (6) ◽  
pp. 566-571 ◽  
Author(s):  
Andrijana Müller ◽  
Jasenka Wagner ◽  
Alenka Hodžić ◽  
Aleš Maver ◽  
Ivana Škrlec ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Risk Factor ◽  
Spontaneous Abortion ◽  
Leptin Receptor ◽  
Recurrent Spontaneous Abortion

scholarly journals Genetic Variation in Circadian Rhythm Genes CLOCK and ARNTL as Risk Factor for Male Infertility

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e59220 ◽  
Author(s):  
Alenka Hodžić ◽  
Momčilo Ristanović ◽  
Branko Zorn ◽  
Cane Tulić ◽  
Aleš Maver ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Risk Factor ◽  
Circadian Rhythm ◽  
Male Infertility

Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke

2006 ◽  
Vol 119 (5) ◽  
pp. 527-540 ◽  
Author(s):  
Martin Horan ◽  
Vicky Newsway ◽  
Yasmin ◽  
Mark D. Lewis ◽  
Tammy E. Easter ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Genetic Variation ◽  
Risk Factor ◽  
Hormone Receptor ◽  
Growth Hormone Receptor

Genetic variation in the KCNMA1 potassium channel α subunit as risk factor for severe essential hypertension and myocardial infarction

2008 ◽  
Vol 26 (11) ◽  
pp. 2147-2153 ◽  
Author(s):  
Marta Tomás ◽  
Esther Vázquez ◽  
José M Fernández-Fernández ◽  
Isaac Subirana ◽  
Cristina Plata ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Genetic Variation ◽  
Risk Factor ◽  
Essential Hypertension ◽  
Potassium Channel ◽  
Α Subunit

scholarly journals Is there a place for nutritional supplements in the treatment of idiopathic male infertility?

2014 ◽  
Vol 86 (3) ◽  
pp. 164 ◽  
Author(s):  
Davide Arcaniolo ◽  
Vincenzo Favilla ◽  
Daniele Tiscione ◽  
Francesca Pisano ◽  
Giorgio Bozzini ◽  
...  
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Nutritional Supplements ◽  
Semen Parameters ◽  
Male Factor ◽  
Treatment Regimens ◽  
Idiopathic Male Infertility ◽  
Infertile Men ◽  
Wide Variability

Objective: Infertility affects 15% of couples in fertile age. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT). The purpose of this study is to review the effects of nutritional supplements as medical treatment for idiopathic male infertility. Material and methods: A Pub Med and Medline review of the published studies utilizing nutritional supplements for the treatment of male infertility has been performed. Results: Clinical trials on Vitamin E, Vitamin A, Vitamin C. Arginine, Carnitine, N-Acetyl-Carnitine, Glutathione, Coenzyme Q10, Selenium and Zinc were reviewed. Although there is a wide variability in selected population, dose regimen and final outcomes, nutritional supplements both alone and in combination seems to be able to improve semen parameters (sperm count, sperm motility and morphology) and pregnancy rate in infertile men. Conclusions: There are rising evidences from published randomized trials and systematic review suggesting that nutritional supplementation may improve semen parameters and the likelihood of pregnancy in men affected by OAT. This improvement, however, is not consistent and there is a wide variation in the treatment regimens used. Well designed and adequately powered RCTs are needed to better clarify the role of nutritional supplements as treatment for male infertility.

scholarly journals Genetic Variation in the Leptin Receptor Gene, Leptin, and Weight Gain in Young Dutch Adults

2003 ◽  
Vol 11 (3) ◽  
pp. 377-386 ◽  
Author(s):  
Caroline T.M. van Rossum ◽  
Barbara Hoebee ◽  
Marleen A. van Baak ◽  
Monica Mars ◽  
Wim H.M. Saris ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Weight Gain ◽  
Leptin Receptor ◽  
Receptor Gene

scholarly journals Environment as a Risk Factor for Male Infertility

2001 ◽  
Vol 1 ◽  
pp. 576-578 ◽  
Author(s):  
Luc Multigner ◽  
Alejandro Oliva
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Male Infertility ◽  
Sperm Production ◽  
Western Countries ◽  
Infertile Couples

Infertility affects 15% of couples in Western countries. Infertility is defined as the inability to conceive after 1 year of attempts without contraception, but it is not synonymous with sterility. Between 30 and 50% of infertile couples are infertile due to male reasons, mainly due to sperm production disorders. Although some risk factors, most of which are infectious, have been identified, there is still much uncertainty about the origins of male infertility.

scholarly journals Genetic variation of the gene coding for microRNA-204 (miR-204) is a risk factor in acute myeloid leukaemia

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Aleksandra Butrym ◽  
Piotr Łacina ◽  
Kazimierz Kuliczkowski ◽  
Katarzyna Bogunia-Kubik ◽  
Grzegorz Mazur
Keyword(s):  
Genetic Variation ◽  
Risk Factor ◽  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Gene Coding ◽  
Acute Myeloid
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