scholarly journals The effect of statins on semen parameters in patients with hypercholesterolemia: a systematic review

Andrology ◽  
2021 ◽  
Author(s):  
Panagiotis Anagnostis ◽  
Dimitrios Papanikolaou ◽  
Pinelopi G. Ioannidou ◽  
Julia K. Bosdou ◽  
Dimitri P. Mikhailidis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Semen Parameters

Antisperm antibodies in infertile men and their effect on semen parameters: A systematic review and meta-analysis

2015 ◽  
Vol 444 ◽  
pp. 29-36 ◽  
Author(s):  
Dong Cui ◽  
Gangwei Han ◽  
Yonggang Shang ◽  
Chengcheng Liu ◽  
Liubing Xia ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Semen Parameters ◽  
Antisperm Antibodies ◽  
Infertile Men

DNA methylation in human sperm: a systematic review

2020 ◽  
Vol 26 (6) ◽  
pp. 841-873 ◽  
Author(s):  
Fredrika Åsenius ◽  
Amy F Danson ◽  
Sarah J Marzi
Keyword(s):  
Systematic Review ◽  
Dna Methylation ◽  
Environmental Factors ◽  
Pregnancy Outcomes ◽  
Human Sperm ◽  
Semen Parameters ◽  
Dna Methylome ◽  
Sperm Dna ◽  
Offspring Health

Abstract BACKGROUND Studies in non-human mammals suggest that environmental factors can influence spermatozoal DNA methylation, and some research suggests that spermatozoal DNA methylation is also implicated in conditions such as subfertility and imprinting disorders in the offspring. Together with an increased availability of cost-effective methods of interrogating DNA methylation, this premise has led to an increasing number of studies investigating the DNA methylation landscape of human spermatozoa. However, how the human spermatozoal DNA methylome is influenced by environmental factors is still unclear, as is the role of human spermatozoal DNA methylation in subfertility and in influencing offspring health. OBJECTIVE AND RATIONALE The aim of this systematic review was to critically appraise the quality of the current body of literature on DNA methylation in human spermatozoa, summarize current knowledge and generate recommendations for future research. SEARCH METHODS A comprehensive literature search of the PubMed, Web of Science and Cochrane Library databases was conducted using the search terms ‘semen’ OR ‘sperm’ AND ‘DNA methylation’. Publications from 1 January 2003 to 2 March 2020 that studied human sperm and were written in English were included. Studies that used sperm DNA methylation to develop methodologies or forensically identify semen were excluded, as were reviews, commentaries, meta-analyses or editorial texts. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) criteria were used to objectively evaluate quality of evidence in each included publication. OUTCOMES The search identified 446 records, of which 135 were included in the systematic review. These 135 studies were divided into three groups according to area of research; 56 studies investigated the influence of spermatozoal DNA methylation on male fertility and abnormal semen parameters, 20 studies investigated spermatozoal DNA methylation in pregnancy outcomes including offspring health and 59 studies assessed the influence of environmental factors on spermatozoal DNA methylation. Findings from studies that scored as ‘high’ and ‘moderate’ quality of evidence according to GRADE criteria were summarized. We found that male subfertility and abnormal semen parameters, in particular oligozoospermia, appear to be associated with abnormal spermatozoal DNA methylation of imprinted regions. However, no specific DNA methylation signature of either subfertility or abnormal semen parameters has been convincingly replicated in genome-scale, unbiased analyses. Furthermore, although findings require independent replication, current evidence suggests that the spermatozoal DNA methylome is influenced by cigarette smoking, advanced age and environmental pollutants. Importantly however, from a clinical point of view, there is no convincing evidence that changes in spermatozoal DNA methylation influence pregnancy outcomes or offspring health. WIDER IMPLICATIONS Although it appears that the human sperm DNA methylome can be influenced by certain environmental and physiological traits, no findings have been robustly replicated between studies. We have generated a set of recommendations that would enhance the reliability and robustness of findings of future analyses of the human sperm methylome. Such studies will likely require multicentre collaborations to reach appropriate sample sizes, and should incorporate phenotype data in more complex statistical models.

The Effect of Subclinical Varicocele on Pregnancy Rates and Semen Parameters: a Systematic Review and Meta-Analysis

2018 ◽  
Vol 19 (7) ◽  
Author(s):  
Taylor P. Kohn ◽  
Samuel J. Ohlander ◽  
Jake S. Jacob ◽  
Tina M. Griffin ◽  
Larry I. Lipshultz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Pregnancy Rates ◽  
Semen Parameters

scholarly journals Semen parameters in men recovered from COVID-19: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Sagar Tiwari ◽  
Niranjan KC ◽  
Sajan Thapa ◽  
Anuja Ghimire ◽  
Sanjeev M Bijukchhe ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sex Hormones ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Sexual Hormones ◽  
Effect Model ◽  
Semen Volume

Abstract Background: The novel beta-coronavirus disease (COVID-19) has infected millions of people globally with high risk among male then female. However, the effect of COVID-19 andrology is still a subject of dispute. We planned to analyze the overall consequences of COVID-19 on semen parameters and male sex hormones.Main text: Systematic search was performed on MEDLINE and Scopus database until June 11 2021. We included observational studies, which reported mean ± standard deviation of the semen parameters and serum sex hormones of those reproductive-aged male recovered from COVID-19 and controls who did not suffered from COVID-19. We used Random-effect model to pool the studies, as heterogeneity was present. Heterogeneity was evaluated by Q test and I2. All studies were assessed with their quality and publication bias.We assessed 966 articles for eligibility and found 7 eligible studies meeting PICO criteria. This include 934 participants with mean age 37.34 ± 10.5. Random-effect model meta-analysis showed that men recovered form COVID-19 had semen parameters less than those who had not suffered from COVID-19. The overall mean difference (MD) [95% confidence interval (CI)] in semen volume, sperm concentration, sperm number, and progressive sperm motility was -0.20 (-0.45, 0.05), -16.59 (-34.82, 1.65), -45.44 (-84.56, -6.31), -1.73(-8.20, 4.75) respectively. Considering sex hormones; Luteinizing hormone and prolactin was found more among those recovered with the significant MD (95% CI) of 3.47 (1.59, 5.35) and 3.21 (1.71, 4.72) respectively.Conclusion: Both the semen parameters and sexual hormones were found to be affected after infected with COVID-19. However, the mechanism for testicular involvement remains doubtful.This systematic review and meta-analysis has been registered in PROSPERO (ID: CRD42021259445)

scholarly journals The Impact of Radiofrequency Waves on Male Infertility: A Systematic Review

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Leili Darvish ◽  
Azadeh Amraee ◽  
Marjan Akhavan Amjadi ◽  
Zahra Atarodi Kashani ◽  
Masoumeh Ghazanfarpour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Male Infertility ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Membrane Integrity ◽  
Semen Parameters ◽  
Cochrane Library ◽  
Negative Effects ◽  
The Impact

Context: As the use of cellphones and other electronic devices increases, concerns about the possible effect of radiofrequency waves on health are growing. Long-term use of the cellphone may have negative effects on sperm quality. Objectives: The purpose of this research was to examine men's infertility due to the effect of radiofrequency waves. Methods: In this systematic review, language restrictions were not considered in searching the databases. Cochrane Library, Google Scholar, PubMed, EMBASE, ProQuest, CINAHL, Science Direct, MEDLINE, and Scopus were used to obtain the data from them. All data were scanned from the year 2000 until 2019. Papers selected for retrieval were evaluated by the Newcastle-Ottawa and CONSORT scales. Results: A total of 14 articles that met the inclusion criteria were ultimately assessed. Motile sperm, sperm vitality and membrane integrity, morphology, volume, total sperm count, sperm concentration, and sperm fertility were found to be influenced by radiofrequency waves. Conclusions: The results showed that RF has detrimental effects on semen parameters and due to an increase in RF wave use currently and its role in male infertility, giving information to men about adverse complications of RF is necessary. Further studies are needed to design the less harmful devices.

scholarly journals Effect of Bariatric Surgery on Semen Parameters: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 24 ◽  
pp. 188-197 ◽  
Author(s):  
Yong Wei ◽  
Quanbing Chen ◽  
Wenhui Qian
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Meta Analysis ◽  
Semen Parameters

scholarly journals Sperm chromatin structure assay and classical semen parameters: systematic review

2010 ◽  
Vol 20 (1) ◽  
pp. 114-124 ◽  
Author(s):  
J.A. Castilla ◽  
S. Zamora ◽  
M.C. Gonzalvo ◽  
J.D. Luna del Castillo ◽  
J.A. Roldan-Nofuentes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chromatin Structure ◽  
Semen Parameters ◽  
Sperm Chromatin ◽  
Sperm Chromatin Structure Assay
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