scholarly journals The Impact of Radiofrequency Waves on Male Infertility: A Systematic Review

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Leili Darvish ◽  
Azadeh Amraee ◽  
Marjan Akhavan Amjadi ◽  
Zahra Atarodi Kashani ◽  
Masoumeh Ghazanfarpour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Male Infertility ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Membrane Integrity ◽  
Semen Parameters ◽  
Cochrane Library ◽  
Negative Effects ◽  
The Impact

Context: As the use of cellphones and other electronic devices increases, concerns about the possible effect of radiofrequency waves on health are growing. Long-term use of the cellphone may have negative effects on sperm quality. Objectives: The purpose of this research was to examine men's infertility due to the effect of radiofrequency waves. Methods: In this systematic review, language restrictions were not considered in searching the databases. Cochrane Library, Google Scholar, PubMed, EMBASE, ProQuest, CINAHL, Science Direct, MEDLINE, and Scopus were used to obtain the data from them. All data were scanned from the year 2000 until 2019. Papers selected for retrieval were evaluated by the Newcastle-Ottawa and CONSORT scales. Results: A total of 14 articles that met the inclusion criteria were ultimately assessed. Motile sperm, sperm vitality and membrane integrity, morphology, volume, total sperm count, sperm concentration, and sperm fertility were found to be influenced by radiofrequency waves. Conclusions: The results showed that RF has detrimental effects on semen parameters and due to an increase in RF wave use currently and its role in male infertility, giving information to men about adverse complications of RF is necessary. Further studies are needed to design the less harmful devices.

scholarly journals Impact of Cigarette Smoking on Sperm Parameters of Infertile Men in Center of Algiers (Capital of Algeria)

2020 ◽  
Vol 10 (4-s) ◽  
pp. 193-196
Author(s):  
Amina Itatahine ◽  
Abbassia Demmouche ◽  
H Maï ◽  
Z.C. Khalloua ◽  
D. Ferrag ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Male Infertility ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Sperm Parameters ◽  
Semen Parameters ◽  
Negative Effects ◽  
Negative Effect ◽  
Pass Through ◽  
And Function

Background : Cigarette smoking has negative effects on male fertility. Toxins from tobacco smoking can potentially affect sperm development and function, with a negative effect on semen parameters. In fact, the components of cigarette smoke pass through the blood-testis barrier and thus induce an alteration of sperm parameters and nucleus quality of the spermatozoa. The aim is to determine a diffence between tobbaco and no tobbaco patient and semen parameters. This article aimed to assess the relationship between smoking and male infertility. Subject and Methods : this is retrospective study focused on the effects of smoking on semen analyses.  377 men (165 non-smokers, 212  smokers) with infertility for at least 1 year were evaluated between  Mars  and  November 2018, in center of algiers (capital of Algeria). Sperm characteristics (concentration, motility, morphology, and volume) were detemined. Results: Sperm concentration, percentage motility and morphology were significantly lower in an infertile Smokers group than the infertile Nonsmokers group. We also observed that the infertility duration were significantly increased (p<0.05) in accordance with the age in an infertile Smokers group.  Our study shows that cigarette smoking is associated with reduced sperm count and motility. Conclusions: Our results suggest that cigarette smoking has an overall negative effect on semen parameters. Our study suggests that men should be advised to abstain from smoking in order to improve reproductive outcomes. Keywords: smoking, semen, male infertility, sperm, humans

scholarly journals Relation between BMI and Semen parameters in male infertility patients in west of Algeria

2020 ◽  
Vol 10 (2-s) ◽  
pp. 64-67
Author(s):  
Dalila Ferrag ◽  
Abbassia Demmouche ◽  
Charaf Khalloua Zine
Keyword(s):  
Body Mass Index ◽  
Male Infertility ◽  
Body Mass ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Infertile Men ◽  
The Mean ◽  
The Impact

Introduction: Body mass index BMI is a risk factor that influences semen quality and reduces male fertility. The aim of this study was to determine the impact of body mass index (BMI) on semen parameters in infertile men. Subject and method: A total of 446 infertile men, the study population was divided into four groups depending on their BMI , underweight (<18.5 kg/), normal weight (18.5-24.99 kg/m2 ), overweight 25-29.99 kg/m2), and obese >30.0 kg/.semen parameters (PH, volume, concentration ,total semen count ,vitality, morphology and motility ) were compared across the four BMI groups. Results: The mean of age was 41.91±6.39, the mean infertility duration was 4.92±3.28, 351(78.7٪) had primary infertility and 95(21.3٪) had secondary infertility. The mean BMI was 29.38± 4.85 and the most of patients 45.2٪ were obese. Conclusion: This study has found evidence of an association between BMI and semen parameters (Sperm concentration, Total sperm count, motility, and vitality) and no correlation between Semen volume, morphology and BMI. Keywords: Body mass index, male infertility, semen quality, west of Algeria

scholarly journals Study of hormone levels and semen parameters in infertile patients and fertile controls from Batna

2017 ◽  
Vol 1 (2) ◽  
pp. 39-40
Author(s):  
Nour El Houda Bousnane ◽  
Ali Chennaf ◽  
Mouloud Yahia
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Public Health Problem ◽  
University Hospital ◽  
Semen Parameters ◽  
Endocrine Disorders ◽  
Major Public Health Problem ◽  
Infertile Men ◽  
The Impact

Background: Male infertility or the inability of a man to procreate is a major public health problem and is a leading cause of marital discord in countries such as Algeria. Endocrine disorders that can be associated with significant medical pathology remain an important factor to be considered in the etiology of male infertility, and those disorders are usually associated with alteration of sperm count or in severe cases with azoospermia. In this study, we are evaluating semen parameters and hormonal levels of patients with idiopathic male infertility and comparing their results with healthy fertile controls. Methods: We aim to study the impact of hormones; follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) and prolactin (PRL) on idiopathic male fertility and their impact on semen parameters, we conducted a study on 71 male subjects with 39 infertile men and 32 fertile controls from the city of Batna (Algeria). Our study lasted six months and was conducted at the University Hospital of Batna and a private analysis laboratory. Results: The results of semen analysis allowed us to determine that the most common pathology in our population is OANTS with a percentage of 21.05% followed by NS and NT with 13.16%; results of the permocytogramme show a predominance of atypical forms of the head with a frequency of 39.21%. Regarding the hormone dosage, prolactin was the most disturbed hormone with an average value of (18 ± 6.221 ng/ml), which is almost pathologic; the other hormones showed some disturbances but to a lesser degree. The results of spermiologique parameters of infertile men compared with fertile controls showed highly significant differences (P≤O.OOO1) regarding motility, concentration vitality, and spermatozoa morphology. The comparison of results of hormones between the two groups revealed differences in LH and prolactin levels; no differences were found regarding FSH and testosterones. Concerning the relationship between hormones and spermiologiques parameters, positive correlations were found between (LH and sperm concentration) (testosterone and sperm concentration), and, finally, a strong correlation was found between the levels of prolactin and the anomalies of intermediate piece of spermatozoa. Conclusion: This study showed that hormonal disorders are not a common cause of male infertility in our study population. It further showed the relative frequencies of the various semen abnormalities during the study period. Also, we found associations between altered semen parameters and pathological levels of some hormones; however, a complementary study with a more subjects is needed.

scholarly journals Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review

2022 ◽  
Vol 12 ◽  
Author(s):  
Yi Lu ◽  
Hao Su ◽  
Jianzhong Zhang ◽  
Yutao Wang ◽  
Hongjun Li
Keyword(s):  
Systematic Review ◽  
Erectile Dysfunction ◽  
Male Infertility ◽  
Sperm Quality ◽  
Sperm Concentration ◽  
Treatment Compliance ◽  
Infertility Treatment ◽  
Cochrane Library ◽  
Infertile Men

Background: Pentoxifylline (PTX) is a member of methylxanthine chemicals and a type of non-selective phosphodiesterase-5 inhibitors, which has been used in male infertility treatment to improve sperm quality and erectile dysfunction (ED) treatment. Mutually tight associations existed between ED and male infertility. Using PTX might kill two birds with one stone by improving sperm quality and erectile function in infertile men with ED.Methods: PubMed, Cochrane Library, EMBASE, and Web of Science were searched by October 2021. Based on available evidence from observational studies and randomized-controlled trials (RCTs), we conducted a systematic review to summarize the efficacy and safety of PTX in treating ED and male infertility. The protocol of the article was registered and updated in PROSPERO (CRD42021291396).Results: From 202 records, eight studies (7 RCTs) evaluating the role of PTX in ED and three studies (2 RCTs) assessing the efficacy of PTX in male infertility were included in the systematic review. Three studies (100.00%) and two studies (100.00%) reported the beneficial role of PTX in improving sperm progressive motility and normal sperm morphology rate, respectively. In contrast, only one study (33.33%) indicated the favorable role of PTX in enhancing sperm concentration. As for ED, three (60.00%) studies supported the treatment role of PTX alone in ED, and two studies (66.67%) favored the combination use of PTX and selective PDE5Is compared with selective PDE5Is alone. Safety analysis showed that PTX was a well-tolerated drug in ED and male infertility treatment.Conclusion: Given the association between ED and male infertility and satisfying findings from available evidence, PTX administration for the simultaneous treatment of poor sperm quality and mild ED in infertile men will highly enhance the treatment compliance. However, the finding should be treated carefully until validated by further studies.

scholarly journals What Is the Impact of Excessive Iodine and Semen Quality in Fertile Men of China: An Association Study 

2021 ◽  
Author(s):  
Ning Wang ◽  
Fang Lv ◽  
Ge Yu ◽  
Cuige Shi ◽  
Shangming Wang ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Male Reproduction ◽  
Semen Parameters ◽  
Human Thyroid ◽  
Urinary Iodine Concentration ◽  
The Impact

Abstract Background: Iodine is an essential element for hormones synthesized by the human thyroid gland. Thyroid hormone deficiency affects all body tissues, including multiple endocrine changes that alter growth hormones, corticotrophin, glucocorticoids, and gonadal function. In many countries, subfertility is an important problem affecting about 10–15% of all couples trying to conceive. Male subfertile factors have accounted for 25–30% of all cases in their studies. The aim of this study was to study the correlation between urinary iodine concentration (UIC) and semen quality of fertile male in China.Methods: semen and urine samples were collected from males who attended a survey for the reproductive physiological constants of male and female in China. All participants were fertile and they should be free from diseases of male reproductive system and thyroid related diseases. We studied the correlation between UIC and semen quality parameters in fertile males and the effect of iodine concentration on male reproduction. Participants were divided into six groups based on UIC. We measured semen parameters and UIC. Semen parameters or time-to-pregnancy (TTP) were analyzed by Spearman correlation, linear regression and multivariable logistic regression. Results: 1089 men were recruited in the study. The mean and median age of participants were 27.46±0.12 and 27±3.88 years, respectively. UIC of 274 (25.16%) men was lower than the UIC of WHO recommended. UIC of 405 men located in the region of WHO recommended. 62.35% of them were not located in the optimal region. Semen concentration and total sperm count were found to decrease when UIC increases when the UIC≥100 ug/L. Conclusions: A male with deficient UIC or excessive UIC has more risk of lower semen quality such as sperm concentration and total sperm count. In addition, if a male with deficient UIC or excessive UIC, his wife has longer TTP than the males who had normal UIC. Deficient UIC associated with lower semen quality and TTP than excessive UIC.

scholarly journals The Association Between Abstinence Period and Semen Parameters: Results in Normal Samples and Different Sperm Pathology

2021 ◽  
Author(s):  
Min Xie ◽  
Silvan Hämmerli ◽  
Kerstin Blickenstorfer ◽  
Brigitte Leeners
Keyword(s):  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Sexual Abstinence ◽  
Normal Morphology ◽  
Few Data ◽  
Total Motile Sperm Count ◽  
Abstinence Period

Abstract Purpose: The length of sexual abstinence seems to influence sperm quality. However, few data on the relevance of abstinence time in pathological sperm samples are available. With our study, we look for associations of abstinence length and semen quality. Methods: We studied semen samples from 4423 men undergoing fertility evaluation. Sperm concentration, percentage of progressively motile spermatozoa, total motile sperm count, percentage of spermatozoa with normal morphology, were compared after each day and 0-2, 3-7 and >7 days of abstinence. Results: We found that a longer abstinence time was related to higher sperm concentration in normal semen samples (P<0.001) and in semen samples with any sperm pathology (P<0.001, P=0.004) with the exception of oligozoospermia (P=0.125). Longer abstinence time was also associated with significantly reduced progressive motility in normal samples (P<0.001) and in cases of teratozoospermia (P<0.001). In normal samples a higher percentage of sperm were morphologically normal after a shorter abstinence period (P=0.03); in oligoasthenoteratozoospermia (OAT) samples, this was the case after a longer abstinence period (P=0.013). Conclusion: A longer abstinence time is associated with higher sperm concentration, whereas sperm motility is optimal after shorter abstinence times; results on morphology are controversial. The recommendation on abstinence time needs to be adjusted in relation to the parameter that needs to be improved.

The Effects of Combined Oral Antioxidants on Male Infertility

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Ali Hadi Sabhan
Keyword(s):  
Male Infertility ◽  
Semen Analysis ◽  
Single Agent ◽  
Sperm Concentration ◽  
Membrane Integrity ◽  
Semen Parameters ◽  
Duration Of Treatment ◽  
Male Patients ◽  
Initiation Of Therapy

High reactive oxygen species (ROS) levels was considered as an important factor of male infertility that can result in DNA damage, decrease motility and damage membrane integrity. The role of antioxidants is to maintain the balance between ROS production and their clearance which improve sperm parameters and enhance male fertility. Sixty six male patients with median age of 29 years with a mean period of infertility of 1.5 year that attend the infertility clinic in Al-Diwaniya Maternity and Pediatric Hospital were selected randomly in this study which extend from January 2013 to October 2014 (22 months).The patients were selected to have idiopathic oligo-astheno-teratozoospermia,they underwent a detailed history,general and genital physical examination,Two semen analyses,baseline hormone profile and scrotal Doppler ultrasound examination. All patients were given a combination of oral antioxidants including vitamin E (400 IU. once daily),coenzyme Q10 (75 mg. tablet twice a day),zinc sulphate (15 mg. tablet three time a day) and L-carnitine (1000 mg. twice a day) for three months duration of treatment. Semen analysis was repeated after three months from initiation of therapy and was evaluated for changes in volume,concentration,motility and morphology in comparison with baseline semen analyses and any pregnancy was also documented. Thirteen patients (19%) get pregnancy after a period of 2 to 3 months,other patients show variable changes in their seminal analysis after 3 months. Thirty patients (45%) show increasing in seminal volume of 0.5 to 2 ml., while the sperm concentration was increased in 28 patients (42%). Twenty two patients (33%) show increasing in motility, morphology was increased in 34 patients (51%).From all 66 patients; 6 patients (9 %) get improvement in all four parameters,while 9 patients (14 %) get improvement in only 3 parameters,20 patients (30 %) get improvement in only 2 parameters,23 patients (35 %) get improvement in only one parameter and 8 patients (12 %) had no improvement in any parameter. This study demonstrates a possible role of combined oral antioxidants in the improvement of semen parameters and pregnancy rate for selected infertile men with superiority for the use of combination of antioxidants rather than single agent treatment.

Body mass index and human sperm quality: neither one extreme nor the other

2017 ◽  
Vol 29 (4) ◽  
pp. 731 ◽  
Author(s):  
E. M. Luque ◽  
A. Tissera ◽  
M. P. Gaggino ◽  
R. I. Molina ◽  
A. Mangeaud ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Normal Weight ◽  
Semen Parameters ◽  
Morbidly Obese ◽  
Epididymal Maturation ◽  
Increased Risk

The aim of the present study was to investigate the still contentious association between body mass index (BMI) and seminal quality. To this end, 4860 male patients (aged 18–65 years; non-smokers and non-drinkers), were classified according to BMI as either underweight (UW; BMI <20 kg m–2; n = 45), normal weight (NW; BMI 20–24.9 kg m–2; n = 1330), overweight (OW; BMI 25–29.9 kg m–2; n = 2493), obese (OB; BMI 30–39.9 kg m–2; n = 926) or morbidly obese (MOB; BMI ≥40 kg m–2; n = 57). Conventional semen parameters and seminal concentrations of fructose, citric acid and neutral α-glucosidase (NAG) were evaluated. The four parameters that reflect epididymal maturation were significantly lower in the UW and MOB groups compared with NW, OW and OB groups: sperm concentration, total sperm count (103.3 ± 11.4 and 121.5 ± 20.6 and vs 157.9 ± 3.6, 152.4 ± 2.7 or 142.1 ± 4.3 spermatozoa ejaculate–1 respectively, P < 0.05), motility (41.8 ± 2.5 and 42.6 ± 2.6 vs 47.8 ± 0.5, 48.0 ± 0.4 or 46.3 ± 0.6 % of motile spermatozoa respectively, P < 0.05) and NAG (45.2 ± 6.6 and 60.1 ± 7.9 vs 71.5 ± 1.9, 64.7 ± 1.3 or 63.1 ± 2.1 mU ejaculate-1 respectively, P < 0.05). Moreover, the percentage of morphologically normal spermatozoa was decreased in the MOB group compared with the UW, NW, OW and OB groups (4.8 ± 0.6% vs 6.0 ± 0.8%, 6.9 ± 0.1%, 6.8 ± 0.1 and 6.4 ± 0.2%, respectively; P < 0.05). In addition, men in the MOB group had an increased risk (2.3- to 4.9-fold greater) of suffering oligospermia and teratospermia (P < 0.05). Both morbid obesity and being underweight have a negative effect on sperm quality, particularly epididymal maturation. These results show the importance of an adequate or normal bodyweight as the natural best option for fertility, with both extremes of the BMI scale as negative prognostic factors.

scholarly journals The Efficacy and Safety of Letrozole or Anastrozole in The Treatment of Specific Male Infertility Patients: Meta-Analysis and Systematic Review

2021 ◽  
Author(s):  
Bin Guo ◽  
Jiao-jiao Li ◽  
Ya-ling Ma ◽  
Yu-tao Zhao ◽  
Jian-guo Liu
Keyword(s):  
Systematic Review ◽  
Male Infertility ◽  
Pregnancy Rate ◽  
Sperm Count ◽  
Meta Analysis ◽  
Sperm Concentration ◽  
Efficacy And Safety ◽  
Testosterone Undecanoate ◽  
Testosterone Levels ◽  
Infertility Patients

Abstract Background: Letrozole (LE) or anastrozole (AZ) is clinically beneficial in male infertility patients with a low testosterone-estradiol ratio (T/E2). Many scholars believe it has the potential to become one of the effective drugs to treat male infertility. But some relevant research results are different or even the opposite. Study Question: The purpose of this report is to evaluate the efficacy and safety of letrozole or anastrozole in the treatment of specific male infertility patients. Data Sources: We performed a comprehensive literature search using PubMed, Embase, Cochrane, CNKI, VIP, CBM, and Wanfang Date through August 2021 for all studies.Study Design: We conducted a systematic review with meta- analysis of the all available literature reporting sperm conventional parameters, gonadotropin and testosterone levels, and/or the pregnancy rate. Results: The total of 10 studies involving 280 patients were included. LE or AZ administration increased significantly sperm concentration, total sperm count, and serum luteinizing hormone, follicle-stimulating hormone, testosterone levels and T / E2 compared with baseline values, but E2 levels were significantly reduced. In contrast, LE or AZ did not have any significant effect on sperm concentration and motility and pregnancy rate, but improved total sperm count, sperm morphology, compared to the control group, which included studies done with Selective estrogen receptor modulators (SEMR) or testosterone undecanoate (TU). Conclusion: LE or AZ may be effective in the treatment of low T / E2 male infertility, perhaps better than other anti-estrogen or exogenous testosterone supplementation. In addition, we should pay special attention to the changes of E2 during treatment.

scholarly journals The Role of Exercise to Reduce the Impact of Diabetes in the Seminal Quality: A Systematic Review

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 159
Author(s):  
Ana Myriam Lavín-Pérez ◽  
Daniel Collado-Mateo ◽  
Santos Villafaina ◽  
Violeta Calle-Guisado
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Physical Exercise ◽  
Exercise Intervention ◽  
Sperm Quality ◽  
Sperm Count ◽  
Group 2 ◽  
Induced Apoptosis ◽  
Meta Analyses ◽  
The Impact

Background and Objectives: One of the most relevant consequences of diabetes mellitus is the temporal or complete infertility which can happen in young individuals. Therefore, the current systematic review aimed to investigate the effects of exercise to reduce the impact of Type 2 Diabetes Mellitus (T2DM) in seminal quality and related parameters. Materials and Methods: A systematic search was conducted in Pubmed and Web of Science databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (1) the study included at least one experimental and one comparison group, (2) the sample of the study was comprised of humans or animals with diabetes mellitus, (3) an intervention based on physical exercise was conducted, and (4) the study reported variables related to the seminal quality. Results: A total of 115 articles were identified. However, only six accomplished the inclusion and exclusion criteria. This systematic review includes a sample size of 260 participants (180 rats and 80 humans). Intervention ranged from 6 to 14 weeks, with 3–6 days per week. All interventions performed endurance training (50–70% VO2max or maximum heart rate). Physical exercise increased sperm count, motility, and morphology, as well as improved testosterone, Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH) levels. Moreover, physical exercise intervention reduced the percentages of sperms with negative Tubular Differentiation Index (TDI) and Spermiogenesis Index (SPI), DNA fragmentation, and also ameliorated the diabetes-induced apoptosis and improved sperm apoptosis index. Conclusions: Physical exercise could ameliorate diabetic pathological effects on sperm quality and related parameters that cause infertility or subfertility conditions. However, further homogeneous studies are needed to confirm these findings.

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