Could lymphocyte to C‐reactive protein ratio predict the prognosis in patients with gastric cancer?

2021 ◽  
Author(s):  
Yavuz Selim Angin ◽  
Murat Yildirim ◽  
Fatih Dasiran ◽  
Ismail Okan
Keyword(s):  
Gastric Cancer ◽  
C Reactive Protein ◽  
Protein Ratio ◽  
Reactive Protein

scholarly journals The Association of the Lymphocyte-to-C-Reactive-Protein Ratio With Gastric Cancer Patients Who Receive Curative Treatment

In Vivo ◽  
2021 ◽  
Vol 36 (1) ◽  
pp. 482-489
Author(s):  
TORU AOYAMA ◽  
MASATO NAKAZANO ◽  
SHINSUKE NAGASAWA ◽  
KENTARO HARA ◽  
KEISUKE KOMORI ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Curative Treatment ◽  
C Reactive Protein ◽  
Protein Ratio ◽  
Reactive Protein ◽  
Gastric Cancer Patients

Lymphocyte-to-C-reactive protein ratio and score are clinically feasible nutrition-inflammation markers of outcome in patients with gastric cancer

2020 ◽  
Vol 39 (4) ◽  
pp. 1209-1217 ◽  
Author(s):  
Yoshinaga Okugawa ◽  
Yuji Toiyama ◽  
Akira Yamamoto ◽  
Tsunehiko Shigemori ◽  
Takashi Ichikawa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Inflammation Markers ◽  
C Reactive Protein ◽  
Protein Ratio ◽  
Reactive Protein

scholarly journals Prognostic value of lymphocyte-to-C-reactive protein ratio in patients with gastric cancer after surgery: a multicentre study

2020 ◽  
Vol 50 (10) ◽  
pp. 1141-1149 ◽  
Author(s):  
Chuan-bing Cheng ◽  
Qu-xia Zhang ◽  
Lv-Ping Zhuang ◽  
Jian-wei Sun
Keyword(s):  
Gastric Cancer ◽  
Overall Survival ◽  
Cancer Patients ◽  
Prognostic Marker ◽  
Predictive Value ◽  
Radical Gastrectomy ◽  
C Reactive Protein ◽  
Protein Ratio ◽  
Reactive Protein ◽  
Gastric Cancer Patients

Abstract Objective The immune inflammation-based score is recognized as a prognostic marker for cancer. However, the most accurate prognostic marker for patients with gastric cancer remains undetermined. We aimed to evaluate the predictive value of the lymphocyte-to-C-reactive protein ratio for outcomes in gastric cancer patients after radical gastrectomy. Methods A total of 607 gastric cancer patients treated at three Chinese institutions were included. Receiver operating characteristic curves were generated, and the areas under the curve were calculated to compare the predictive value among the inflammation-based score, lymphocyte-to-C-reactive protein ratio, C-reactive protein/albumin and neutrophil-lymphocyte, platelet-lymphocyte and lymphocyte-monocyte ratios. Cox regression was performed to determine the prognostic factors for overall survival. Results The median follow-up time was 63 months (range: 1–84 months). The optimal cut-off value for lymphocyte-to-C-reactive protein ratio was 0.63. The patients were divided into the LCR <0.63 (LLCR, n = 294) group and the LCR ≥0.63 (HLCR, n = 313) group. LLCR was significantly correlated with poor clinical characteristics. Compared with inflammation-based score, lymphocyte-to-C-reactive protein ratio had the highest areas under the curve (0.695). Patients with LLCR experienced more post-operative complications than the HLCR group (20.4 vs. 12.1%, P = 0.006). Multivariate analysis showed that a higher lymphocyte-to-C-reactive protein ratio (HR: 0.545, 95%CI: 0.372–0.799, P = 0.002) was associated with better overall survival. The HLCR group had higher 5-year overall survival rate than the LLCR group (80.5 vs. 54.9%, P < 0.001). Conclusions Preoperative lymphocyte-to-C-reactive protein ratio levels can effectively predict the short-term and oncological efficacy of gastric cancer patients after radical gastrectomy with a predictive value significantly better than other inflammation-based score.

Lymphocyte C-reactive protein ratio: A new biomarker to predict early complications after gastrointestinal oncologic surgery

2021 ◽  
pp. 1-9
Author(s):  
Murat Yildirim ◽  
Bulent Koca
Keyword(s):  
Colorectal Cancer ◽  
Postoperative Complications ◽  
Inflammatory Markers ◽  
Operation Time ◽  
C Reactive Protein ◽  
Oncologic Surgery ◽  
Protein Ratio ◽  
Colorectal Cancer Surgery ◽  
Neutrophil Lymphocyte Ratio ◽  
Reactive Protein

BACKGROUND: Lymphocyte-to-C-reactive protein ratio (LCR) has been used as a post-surgical prognostic biomarker in patients with gastric and colorectal cancer. However, its relationship with early postoperative complications in these patients is unknown. In this study, we aimed to reveal the relationship between LCR and postoperative complications. METHODS: Eighty-one patients operated for stomach and colorectal cancer between January 2020 and August 2020 were prospectively analyzed. On preoperative and postoperative days 1, 3 and 5, other inflammatory parameters, mainly LCR, neutrophil lymphocyte ratio (NLR), were recorded. The patients were divided into two groups according to Clavien-Dindo classification as stage III and higher complications major, stage I-II/non-complication minor. RESULTS: Fifty seven patients were operated for colorectal cancer, 24 patients for gastric cancer. The mean age of the patients was 65.6 ± 12.6, 34.6% of them was women. Age, operation time and hospital stay were significantly different between the groups (p= 0.004, p= 0.002, p< 0.001). Major complications developed in 18 patients. On postoperative day 5, LCR found superior diagnostic accuracy in predicting major postoperative complications compared to other inflammatory markers. On the postoperative 5th day, the cut-off value of LCR was 0.0034, 88.8% (71.9–94.8) sensitivity, and 85.7% (73.6–95.4) selectivity. CONCLUSION: Among different inflammatory markers, postoperative LCR is a safe and effective predictor of postoperative complications, especially after gastric and colorectal cancer surgery on day 5.

scholarly journals Clinical and prognostic implications of pretreatment albumin to C-reactive protein ratio in patients with hepatocellular carcinoma

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mian-Tao Wu ◽  
Su-Yin He ◽  
Shu-Lin Chen ◽  
Lin-Fang Li ◽  
Zheng-Qiang He ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
C Reactive Protein ◽  
Protein Ratio ◽  
Reactive Protein ◽  
Prognostic Implications

scholarly journals C-reactive protein on postoperative day 3 as a predictor of infectious complications following gastric cancer resection

2015 ◽  
Vol 19 (1) ◽  
pp. 293-301 ◽  
Author(s):  
Yuji Shishido ◽  
Kazumasa Fujitani ◽  
Kazuyoshi Yamamoto ◽  
Motohiro Hirao ◽  
Toshimasa Tsujinaka ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Infectious Complications ◽  
C Reactive Protein ◽  
Cancer Resection ◽  
Reactive Protein ◽  
Gastric Cancer Resection

scholarly journals 140P Preoperative and postoperative C-reactive protein levels predict recurrence and chemotherapy benefit in gastric cancer

2020 ◽  
Vol 31 ◽  
pp. S1296
Author(s):  
L-L. Shen ◽  
Y-H. Tang ◽  
W-W. Qiu ◽  
J. Lu ◽  
C-H. Zheng ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Prognostic role of the pretreatment C-reactive protein/albumin ratio in gastric cancer

Medicine ◽  
2020 ◽  
Vol 99 (10) ◽  
pp. e19362
Author(s):  
Xuanxuan Yang ◽  
Xing Song ◽  
Luo Zhang ◽  
Changping Wu
Keyword(s):  
Gastric Cancer ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Albumin Ratio ◽  
Reactive Protein

scholarly journals C-reactive protein elevation ratio as an early predictor of postoperative severe complications after laparoscopic gastrectomy for gastric cancer: a retrospective study

BMC Surgery ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hiroaki Tanaka ◽  
Tatsuro Tamura ◽  
Takahiro Toyokawa ◽  
Kazuya Muguruma ◽  
Naoshi Kubo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Retrospective Study ◽  
Laparoscopic Gastrectomy ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Early Predictor
Sign in / Sign up

Export Citation Format

Share Document