Utilization of extracorporeal life support for diffuse alveolar damage and diffuse alveolar hemorrhage: A systematic review

2020 ◽  
Author(s):  
Haritha G. Reddy ◽  
Elizabeth J. Maynes ◽  
Abhiraj Saxena ◽  
Melissa A. Austin ◽  
Thomas J. O’Malley ◽  
...  
Perfusion ◽  
2019 ◽  
Vol 34 (6) ◽  
pp. 523-525 ◽  
Author(s):  
Samuel M Galvagno ◽  
Nirav G Shah ◽  
Christopher R Cornachione ◽  
Kristopher B Deatrick ◽  
Michael A Mazzeffi ◽  
...  

Introduction: Diffuse alveolar damage is the histologic hallmark for the acute phase of acute respiratory distress syndrome and can occasionally present as diffuse alveolar hemorrhage. Case report: We report a patient with diffuse alveolar hemorrhage and acute respiratory distress syndrome requiring veno-venous extracorporeal life support for 210 days, who was successfully treated for a period of 130 consecutive days without intravenous anticoagulation. Discussion: Although there are a few brief reports detailing long extracorporeal life support runs, the literature is largely devoid of data regarding long-term extracorporeal life support without full systemic anticoagulation. Regular inspection of the extracorporeal membrane oxygenation circuit is critical because externally visible thrombi may predict internal thrombus generation with the potential for systemic embolization or abrupt oxygenator failure. In our case, multiple circuit and oxygenators changes were required. Conclusion: We have demonstrated that a patient with a contraindication for systemic anticoagulation can safely have veno-venous extracorporeal life support for prolonged periods without catastrophic thrombotic complications.


Resuscitation ◽  
2020 ◽  
Vol 146 ◽  
pp. 132-137 ◽  
Author(s):  
Thomas J. O’Malley ◽  
Jae Hwan Choi ◽  
Elizabeth J. Maynes ◽  
Chelsey T. Wood ◽  
Nicholas D. D’Antonio ◽  
...  

2016 ◽  
Vol 42 (12) ◽  
pp. 1922-1934 ◽  
Author(s):  
Dagmar M. Ouweneel ◽  
Jasper V. Schotborgh ◽  
Jacqueline Limpens ◽  
Krischan D. Sjauw ◽  
A. E. Engström ◽  
...  

2015 ◽  
Vol 41 (6) ◽  
pp. 994-1003 ◽  
Author(s):  
Jonathan D. Marhong ◽  
Laveena Munshi ◽  
Michael Detsky ◽  
Teagan Telesnicki ◽  
Eddy Fan

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Robert Ta ◽  
Romulo Celli ◽  
A. Brian West

The case of a 16-year-old African-American girl with systemic lupus erythematosus, who developed diffuse alveolar hemorrhage with fatal consequences, is described. Diffuse alveolar hemorrhage is a rare but serious complication of systemic lupus. It occurs in three distinct but overlapping phenotypes, acute capillaritis, bland pulmonary hemorrhage, and diffuse alveolar damage, each of which is associated with a different group of underlying conditions. Diffuse alveolar hemorrhage is a medical emergency: choice of treatment depends on early diagnosis and determination of the underlying etiology. Acute infection, superimposed on diffuse alveolar hemorrhage in the setting of immune compromise, is often a terminal event, as in this case.


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