Effects of oral administration of Spirulina platensis and probiotics on serum immunity indexes, colonic immune factors, fecal odor, and fecal flora in mice

2021 ◽  
Vol 92 (1) ◽  
Author(s):  
Lingyan Zhang ◽  
Xing Tao Zhang ◽  
Pingting Jin ◽  
Hongbo Zhao ◽  
Xue Liu ◽  
...  
Keyword(s):  
Oral Administration ◽  
Spirulina Platensis ◽  
Fecal Flora ◽  
Immune Factors

scholarly journals THE EFFECT OF ANTIBACTERIAL DRUGS ON THE FECAL FLORA OF MICE

1963 ◽  
Vol 117 (2) ◽  
pp. 231-243 ◽  
Author(s):  
Rene Dubos ◽  
Russell W. Schaedler ◽  
Mallory Stephens
Keyword(s):  
Oral Administration ◽  
Wheat Gluten ◽  
Fecal Flora ◽  
Antibacterial Drugs ◽  
Gram Negative ◽  
Swiss Mice ◽  
Large Numbers ◽  
Very High

Oral administration of penicillin, terramycin, or chloramphenicol to NCS mice rapidly brought about profound changes in their fecal flora. The lactobacilli disappeared completely, whereas the numbers of enterococci and Gram-negative bacilli reached very high levels. In contrast, no effect on the fecal flora could be detected following administration of isoniazid in any amount. The intensity and duration of the effects on the fecal flora were related to the type of drug and to the amount of it administered. Chloramphenicol produced disturbances which were less profound and of shorter duration than those produced by penicillin or terramycin. The duration of the disturbances in the fecal flora produced by antibacterial drugs was markedly conditioned by the nutritional regimen. The fecal flora returned to its pretreatment state (large numbers of lactobacilli, few enterococci, and few Gram-negative bacilli) within less than 4 weeks after discontinuing the drug when the mice were fed a complex diet of ill defined composition (commercial pellets). Contrariwise, the fecal flora remained markedly different from that of control mice when the animals were fed semisynthetic diets containing as source of protein either 15 per cent casein or 15 per cent wheat gluten (both supplemented with cystine); or 15 per cent wheat gluten supplemented with lysine, threonine, and cystine. The fecal flora of mice treated with penicillin contained large numbers of lactose-fermenting Gram-negative bacilli, not found in the untreated animals. These lactose fermenters persisted for several months after discontinuance of the drug in mice fed either the casein or gluten diets, but they disappeared rapidly from mice fed pellets. Similar results, although less striking, were obtained with Swiss mice from colonies maintained under usual conditions, and therefore having a fecal flora more complex than that of NCS mice.

scholarly journals Effects of Spirulina platensis on alloxan induced diabetic rats

2018 ◽  
Vol 29 (2) ◽  
pp. 139-146
Author(s):  
SMAK Hussaini ◽  
MI Hossain ◽  
MS Islam ◽  
K Rafiq
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Oral Administration ◽  
Lipid Profile ◽  
Spirulina Platensis ◽  
Profile Analysis ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Male Rats ◽  
Control Group

The study was undertaken to investigate the effects of Spirulina platensis on body weight, blood glucose and lipid profile on alloxan induced diabetic rats. Fifteen Long Evans male rats at six weeks of age were used for the experiment. Diabetes was induced by intraperitoneal injection of alloxan@ 150 mg/kg and experiment was carried out for a period of 6 weeks. Rats were divided into three groups of 5 rats each. The groups were i)healthy control, ii) diabetic control with both receiving rats’ pellet as supplement, and iii) diabetic treated with oral administration of Spirulina platensis  @ 400 mg/kg bwt. Results from the study showed that Spirulina platensis reduced blood glucose significantly (P<0.01) and increased body weight significantly (P<0.05) in contrast to diabetic control group after 6 weeks. Lipid profile analysis with Spirulina platensis @ 400 mg/kg showed that total cholesterol, plasma triglycerides, and LDL were lowered significantly   compared to diabetic groups in contrast to HDL levels which were increased following the use of Spirulina platensis. Our findings showed that oral administration of Spirulina platensis could reduce the adverse effect of alloxan induced diabetes in rats. Based on this research it can be concluded that Spirulina platensis has antihyperglycemic and hypolipidimic effects in alloxan induced diabetic rats.Progressive Agriculture 29 (2): 139-146, 2018

FECAL FLORA OF MAN AFTER ORAL ADMINISTRATION OF CHLORTETRACYCLINE OR OXYTETRACYCLINE

1955 ◽  
Vol 95 (1) ◽  
pp. 74 ◽  
Author(s):  
WEI-PING LOH
Keyword(s):  
Oral Administration ◽  
Fecal Flora

Effect of Long-term Oral Administration of an Immunostimulant Diet on Innate Immunity in Sea Bass (Dicentrarchus labrax)

2000 ◽  
Vol 47 (10) ◽  
pp. 745-751 ◽  
Author(s):  
M. Bagni ◽  
L. Archetti ◽  
M. Amadori ◽  
G. Marino
Keyword(s):  
Innate Immunity ◽  
Oral Administration ◽  
Dicentrarchus Labrax ◽  
Sea Bass

Correction of Steatorrhea in Bile Fistula Dogs by Duodenal and Oral Administration of Bile Substitutes

1951 ◽  
Vol 19 (3) ◽  
pp. 558-563 ◽  
Author(s):  
G.W. Searle ◽  
J.H. Annegers
Keyword(s):  
Oral Administration ◽  
Bile Fistula
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