scholarly journals Safety, tolerability and pharmacokinetics and pharmacodynamics of HL2351, a novel hybrid fc‐fused interleukin‐1 receptor antagonist, in healthy subjects: A first‐in‐human study

2020 ◽  
Vol 86 (2) ◽  
pp. 372-379
Author(s):  
Jaeseong Oh ◽  
Ki Young Huh ◽  
Young‐Gyu Cho ◽  
Ji‐Eun Cha ◽  
Se‐Jin Kim ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Healthy Subjects ◽  
Interleukin 1 ◽  
Human Study ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Author’s Reply to: “Comment on: Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Chinese Healthy Subjects”

2019 ◽  
Vol 44 (5) ◽  
pp. 723-724
Author(s):  
Ran Xie ◽  
Yang Zhang ◽  
Nan Zhao ◽  
Shuang Zhou ◽  
Xin Wang ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Healthy Subjects ◽  
Interleukin 1 ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Pharmacokinetics, pharmacodynamics and tolerability of HL2351, a hybrid Fc-fused human Interleukin-1 receptor antagonist, in healthy subjects

2018 ◽  
Vol WCP2018 (0) ◽  
pp. PO2-5-18
Author(s):  
Ki Young Huh ◽  
Jaeseong Oh ◽  
Eunwoo Kim ◽  
Ji-Eun Cha ◽  
Se-Jin Kim ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Healthy Subjects ◽  
Interleukin 1 ◽  
Interleukin 1 Receptor Antagonist

Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation

Stem Cells ◽  
2015 ◽  
Vol 34 (2) ◽  
pp. 483-492 ◽  
Author(s):  
Patricia Luz-Crawford ◽  
Farida Djouad ◽  
Karine Toupet ◽  
Claire Bony ◽  
Marcella Franquesa ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
B Cell ◽  
Receptor Antagonist ◽  
Macrophage Polarization ◽  
Interleukin 1 ◽  
B Cell Differentiation ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Seizures and memory impairment induced by patient‐derived anti‐N‐methyl‐D‐aspartate receptor antibodies in mice are attenuated by anakinra, an interleukin‐1 receptor antagonist

Epilepsia ◽  
2021 ◽  
Author(s):  
Olga Taraschenko ◽  
Howard S. Fox ◽  
Anastasia Zekeridou ◽  
Sean J. Pittock ◽  
Ember Eldridge ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Memory Impairment ◽  
Interleukin 1 ◽  
Interleukin 1 Receptor Antagonist ◽  
Aspartate Receptor ◽  
Receptor Antibodies
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