scholarly journals Prospective longitudinal course of aggression among adults with bipolar disorder

2013 ◽  
Vol 16 (3) ◽  
pp. 262-269 ◽  
Author(s):  
Javier Ballester ◽  
Benjamin Goldstein ◽  
Tina R Goldstein ◽  
Haifeng Yu ◽  
David Axelson ◽  
...  
2012 ◽  
Vol 43 (6) ◽  
pp. 1151-1160 ◽  
Author(s):  
V. M. Goghari ◽  
M. Harrow ◽  
L. S. Grossman ◽  
C. Rosen

BackgroundHallucinations are a major aspect of psychosis and a diagnostic feature of both psychotic and mood disorders. However, the field lacks information regarding the long-term course of hallucinations in these disorders. Our goals were to determine the percentage of patients with hallucinations and the relationship between hallucinations and recovery, and work attainment.MethodThe present study was a prospective evaluation of the 20-year trajectory of hallucinations in 150 young patients: 51 schizophrenia, 25 schizoaffective, 25 bipolar with psychosis, and 49 unipolar depression. The patients were studied at an index phase of hospitalization for hallucinations, and then reassessed longitudinally at six subsequent follow-ups over 20 years.ResultsThe longitudinal course of hallucinations clearly differentiated between schizophrenia and bipolar disorder with psychosis, and suggested some diagnostic similarities between schizophrenia and schizoaffective disorder, and between bipolar disorder and schizoaffective disorder and depression. Frequent or persistent hallucinatory activity over the 20-year period was a feature of 40–45% of schizophrenia patients. The early presence of hallucinations predicted the lack of future periods of recovery in all patients. Increased hallucinatory activity was associated with reduced work attainment in all patients.ConclusionsThis study provides data on the prospective longitudinal course of hallucinations, which were previously unavailable to the field, and are one of the key features of psychosis in major psychiatric disorders. This information on the clinical course of major psychiatric disorders can inform accurate classification and diagnosis.


2020 ◽  
Vol 274 ◽  
pp. 1113-1121 ◽  
Author(s):  
María Reinares ◽  
Isabella Pacchiarotti ◽  
Brisa Solé ◽  
Aitana García-Estela ◽  
Adriane R. Rosa ◽  
...  

2013 ◽  
Vol 15 (3) ◽  
pp. 284-293 ◽  
Author(s):  
Benjamin I Goldstein ◽  
Shang-Min Liu ◽  
Ayal Schaffer ◽  
Regina Sala ◽  
Carlos Blanco

2016 ◽  
Vol 55 (12) ◽  
pp. 1064-1072.e6 ◽  
Author(s):  
Xenia Borue ◽  
Carla Mazefsky ◽  
Brian T. Rooks ◽  
Michael Strober ◽  
Martin B. Keller ◽  
...  

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Anna-Sophie Rommel ◽  
Nina Maren Molenaar ◽  
Janneke Gilden ◽  
Steven A. Kushner ◽  
Nicola J. Westerbeek ◽  
...  

Abstract Objective We aimed to investigate the outcome of postpartum psychosis over a four-year follow-up, and to identify potential clinical markers of mood/psychotic episodes outside of the postpartum period. Methods One hundred and six women with a diagnosis of first-onset mania or psychosis during the postpartum period were included in this prospective longitudinal study. Women were categorized into either (1) recurrence of non-postpartum mood/psychotic episodes or (2) mania/psychosis limited to the postpartum period. We summarize the longitudinal course of the illness per group. We used a logistic regression model to identify clinical predictors of recurrence of mood/psychotic episodes outside of the postpartum period. Results Over two thirds of the women included in this study did not have major psychiatric episodes outside of the postpartum period during follow-up. The overall recurrence rate of mood/psychotic episodes outside the postpartum period was ~ 32%. Of these women, most transitioned to a bipolar disorder diagnosis. None of the women fulfilled diagnostic criteria for schizophrenia or schizophreniform disorder. No clinical markers significantly predicted recurrence outside of the postpartum period. Conclusions For the majority of women with first-onset postpartum psychosis, the risk of illness was limited to the period after childbirth. For the remaining women, postpartum psychosis was part of a mood/psychotic disorder with severe non-postpartum recurrence, mainly in the bipolar spectrum. No clinical predictors for risk of severe episodes outside the postpartum period emerged. Our findings add to previous evidence suggesting a fundamental link between postpartum psychosis and bipolar disorder, which may represent two distinct diagnoses within the same spectrum.


2016 ◽  
Vol Ano 6 ◽  
pp. 6-8
Author(s):  
Bruno Kotzian ◽  
Ives Cavalcante Passos ◽  
Flávio Kapczinski


2001 ◽  
Vol 178 (S41) ◽  
pp. s177-s183 ◽  
Author(s):  
Ralph W. Kupka ◽  
Willem A. Nolen ◽  
Lori L. Altshuler ◽  
Mark A. Frye ◽  
Kirk D. Denicoff ◽  
...  

BackgroundThe Stanley Foundation Bipolar Network (SFBN) evaluates treatments, course and clinical and neurobiological markers of response in bipolar illness.AimsTo give a preliminary summary of emerging findings in these areas.MethodStudies with established and potentially antimanic, antidepressant and mood-stabilising agents range from open case series to double-blind randomised clinical trials, and use the same core assessment methodology, thereby optimising the comparability of the outcomes. The National Institute of Mental Health Life Chart Method is the core instrument for retrospective and prospective longitudinal illness description.ResultsThe first groups of patients enrolled show a considerable degree of past and present symptomatology, psychiatric comorbidity and functional impairment. There are associations of both genetic and early environmental factors with more severe courses of illness. Open case series with add-on olanzapine, lamotrigine, gabapentin or topiramate show a differential spectrum of effectiveness in refractory patients.ConclusionsThe SFBN provides important new data for the understanding and treatment of bipolar disorder.


Sign in / Sign up

Export Citation Format

Share Document