Hidradenitis Suppurativa Area and Severity Index Revised (HASI‐R): psychometric property assessment

2020 ◽  
Author(s):  
N. Goldfarb ◽  
M. A. Lowes ◽  
M. Butt ◽  
T. King ◽  
A. Alavi ◽  
...  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Psychometric Property ◽  
Severity Index ◽  
Property Assessment

Could Residents Adequately Assess the Severity of Hidradenitis Suppurativa? Interrater and Intrarater Reliability Assessment of Major Scoring Systems

Dermatology ◽  
2019 ◽  
Vol 236 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Katarzyna Włodarek ◽  
Aleksandra Stefaniak ◽  
Łukasz Matusiak ◽  
Jacek C. Szepietowski
Keyword(s):  
Interrater Reliability ◽  
Hidradenitis Suppurativa ◽  
Intraclass Correlation ◽  
Scoring Systems ◽  
Staging System ◽  
Severity Index ◽  
Assessment Tools ◽  
Intrarater Reliability ◽  
Global Assessment Scale ◽  
Interrater Variability

A wide variety of assessment tools have been proposed for hidradenitis suppurativa (HS) until now, but none of them meets the criteria for an ideal score. Because there is no gold standard scoring system, the choice of the measure instrument depends on the purpose of use and even on the physician’s experience in the subject of HS. The aim of this study was to assess the intrarater and interrater reliability of 6 scoring systems commonly used for grading severity of HS: the Hurley Staging System, the Refined Hurley Staging, the Hidradenitis Suppurativa Severity Score System (IHS4), the Hidradenitis Suppurativa Severity Index (HSSI), the Sartorius Hidradenitis Suppurativa Score and the Hidradenitis Suppurativa Physician’s Global Assessment Scale (HS-PGA). On the scoring day, 9 HS patients underwent a physical examination and disease severity assessment by a group of 16 dermatology residents using all evaluated instruments. Then, intrarater reliability was calculated using intraclass correlation coefficient (ICC), and interrater variability was evaluated using the coefficient of variation (CV). In all 6 scorings the ICCs were >0.75, indicating high intrarater reliability of all presented scales. The study has also demonstrated moderate agreement between raters in most of the evaluated measure instruments. The most reproducible methods, according to CVs, seem to be the Hurley staging, IHS4, and HSSI. None of the 6 evaluated scoring systems showed a significant advantage over the other when comparing ICCs, and all the instruments seem to be very reliable methods. The interrater reliability was usually good, but the most repeatable results between researchers were obtained for the easiest scales, including Hurley scoring, IHS4 and HSSI.

Cross-cultural and psychometric property assessment of the Moorong Self-Efficacy Scale in Chinese patients with spinal cord injury

2021 ◽  
pp. 1-7
Author(s):  
Mengmeng Jia ◽  
Guilian Chen ◽  
Sumei Xie ◽  
Jie Tang ◽  
Yingmin Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Self Efficacy ◽  
Psychometric Property ◽  
Cross Cultural ◽  
Chinese Patients ◽  
Cord Injury ◽  
Property Assessment

scholarly journals Creation of a severity index for hidradenitis suppurativa that includes a validated quality‐of‐life measure: the HIDRAscore

2020 ◽  
Vol 34 (8) ◽  
pp. 1815-1821 ◽  
Author(s):  
A.V. Marzano ◽  
A. Chiricozzi ◽  
G. Giovanardi ◽  
G. Argenziano ◽  
V. Bettoli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Severity Index ◽  
Life Measure

Deranged Iron Status Evidenced by Iron Deficiency Characterizes Patients with Hidradenitis Suppurativa

Dermatology ◽  
2020 ◽  
Vol 236 (1) ◽  
pp. 52-58
Author(s):  
Malgorzata Ponikowska ◽  
Lukasz Matusiak ◽  
Monika Kasztura ◽  
Ewa A. Jankowska ◽  
Jacek C. Szepietowski
Keyword(s):  
Iron Deficiency ◽  
Disease Severity ◽  
Transferrin Receptor ◽  
Hidradenitis Suppurativa ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Severity Index ◽  
Soluble Transferrin Receptor ◽  
Serum Concentrations ◽  
Autoimmune Processes

Background: Proinflammatory activation and autoimmune processes underlie the pathophysiology of hidradenitis suppurativa (HS). Iron deficiency (ID) is frequently present in inflammation-mediated chronic diseases, irrespective of anemia. Objectives: We aimed to characterize iron status in patients with HS. Methods: Serum concentrations of ferritin, transferrin saturation (Tsat), soluble transferrin receptor and hepcidin were assessed as the biomarkers of iron status in 74 patients with HS and 44 healthy subjects. ID was defined as ferritin <100 µg/L or ferritin 100–299 µg/L with Tsat <20% (following the definition used in the other studies in chronic disease). Results: Compared with controls, patients with HS demonstrated a deranged iron status as evidenced by decreased levels of ferritin (91 ± 87 vs. 157 ± 99 µg/L), Tsat (21.5 ± 10.8 vs. 42.2 ± 11.7%) and hepcidin (31.3 ± 25.9 vs. 44.2 ± 22.0 ng/mL) (all p < 0.05 vs. controls). There was also a trend toward higher values of soluble transferrin receptor (1.23 ± 0.35 vs. 1.12 ± 0.19 mg/L) (p = 0.09 vs. controls). Disease severity (assessed with the Hidradenitis Suppurativa Severity Index and the 3-degree Hurley scale) did not differentiate iron status biomarkers. ID was present in 75% of HS patients, and its prevalence was not related with disease severity (Hurley I/II/III – 82 vs. 73 vs. 67%). In HS, none of the iron status biomarkers correlated with the levels of interleukin-6 (a marker of proinflammatory activation). Conclusions: The majority of HS patients demonstrate derangements in iron status typical of ID. These abnormalities are neither related to proinflammatory activation nor associated with disease severity. Whether it may have a therapeutic impact needs to be further studied.

Coprevalence of Hidradenitis Suppurativa and Psoriasis: Detailed Demographic, Disease Severity and Comorbidity Pattern

Dermatology ◽  
2020 ◽  
Vol 237 (5) ◽  
pp. 759-768
Author(s):  
Andreas Pinter ◽  
Mana Sarlak ◽  
Kim Nicola Zeiner ◽  
Bartosz Malisiewicz ◽  
Roland Kaufmann ◽  
...  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Psychiatric Comorbidity ◽  
Skin Diseases ◽  
Severity Index ◽  
University Hospitals ◽  
Score System ◽  
Male Ratio ◽  
Increased Risk ◽  
Positive Effect ◽  
First Diagnosis

<b><i>Background and Objectives:</i></b> Hidradenitis suppurativa (HS) and plaque psoriasis (Pso) are supposed to have a coprevalence. However, data showing a more detailed description of patients with both diseases are rare. In this study, we characterized patients with both skin diseases in terms of onset, disease course, severity, concomitant diseases and therapeutical management. <b><i>Patients and Methods:</i></b> Data from 28 patients with a confirmed codiagnosis of HS and Pso from 2 university hospitals presented between 2015 and 2019 were evaluated retrospectively. For further characterization, patients were divided into different cohorts depending on whether HS or Pso was diagnosed as the first disease. <b><i>Results:</i></b> The average age of patients with a coprevalence of both diseases was 44.4 years with a female/male ratio of 1:1.15. Fifteen patients were diagnosed first with HS at an average age of 22.8 years, 13 patients first showed symptoms of Pso at a mean age of 21.7 years. The average time to the onset of the corresponding second disease was 14.3 years. Patients with HS as first disease showed a significantly severer form of HS compared to patients with a first diagnosis of Pso (mean highest International Hidradenitis Suppurativa Severity Score System: 23.5 vs. 8.2; <i>p</i> = 0.02). Severity of psoriatic disease in patients with HS at first diagnosis was numerically lower but not significant compared to the cohort with Pso at first diagnosis (mean highest Psoriasis Area and Severity Index: 7.8 vs. 13.2; <i>p</i> = 0.299). The most frequent comorbidity in all patients was obesity (64.3%; mean body mass index: 32.2) followed by psychiatric complaints (25%) and psoriatic arthritis (21.4%). Adalimumab was the most commonly used drug that had a positive effect on both diseases, HS and Pso. <b><i>Conclusions:</i></b> In patients with a coprevalence of HS and Pso, the disease which occurs first appears to take a severer course, with an increased risk of development of obesity and psychiatric comorbidity in both cohorts.

scholarly journals Hidradenitis Suppurativa Area and Severity Index ( HASI ): a pilot study to develop a novel instrument to measure the physical signs of hidradenitis suppurativa

2019 ◽  
Author(s):  
N. Goldfarb ◽  
J.R. Ingram ◽  
G.B.E. Jemec ◽  
H.B. Naik ◽  
V. Piguet ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hidradenitis Suppurativa ◽  
Severity Index

Host-defense mechanisms in hidradenitis suppurativa

1977 ◽  
Vol 113 (4) ◽  
pp. 450-453 ◽  
Author(s):  
V. C. Dvorak
Keyword(s):  
Host Defense ◽  
Defense Mechanisms ◽  
Hidradenitis Suppurativa

The role of depilation and deodorants in hidradenitis suppurativa

1982 ◽  
Vol 118 (2) ◽  
pp. 101-102 ◽  
Author(s):  
W. P. Morgan
Keyword(s):  
Hidradenitis Suppurativa
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