Retiform purpuric plaques with central ulceration over the breasts

2020 ◽  
Vol 45 (8) ◽  
pp. 1072-1076
Author(s):  
C. J. Schwartz ◽  
G. Bladuell ◽  
A. Weinkle ◽  
G. E. Morey ◽  
P. Rodriguez‐Waikus ◽  
...  
Keyword(s):  
Central Ulceration

scholarly journals Cutaneous blastomycosis: a clue to a systemic disease

2013 ◽  
Vol 88 (2) ◽  
pp. 287-289 ◽  
Author(s):  
Alex G Ortega-Loayza ◽  
Tuyet Nguyen
Keyword(s):  
Back Pain ◽  
Skin Biopsy ◽  
Ct Scan ◽  
Systemic Disease ◽  
Central Ulceration

A 55-year-old male presented with back pain and slightly tender annular plaques with central ulceration on his face. A skin biopsy revealed scattered yeast with broad based buds. A CT scan of the abdomen revealed a pathologic T12 fracture. Tissue obtained from the spine confirmed budding yeasts. The patient was diagnosed with disseminated blastomycosis. The patient was treated with amphotericin and itraconazole and completely recovered.

scholarly journals Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease

2015 ◽  
Vol 7 (2) ◽  
pp. 100-106 ◽  
Author(s):  
Tueboon Sriphojanart ◽  
Vasanop Vachiramon
Keyword(s):  
Bypass Surgery ◽  
Tight Control ◽  
Atherosclerotic Vascular Disease ◽  
Reticular Dermis ◽  
Heavy Smoking ◽  
Spindle Cells ◽  
Vascular Bypass ◽  
Vascular Proliferation ◽  
Central Ulceration ◽  
The Right

Diffuse dermal angiomatosis (DDA) is a benign, acquired, reactive vascular proliferation. DDA is clinically characterized by painful purpuric plaque with central ulceration. The histopathologic hallmark is diffuse proliferation of endothelial cells that are arranged interstitially between collagen bundles of the reticular dermis. DDA has been reported in association with peripheral atherosclerotic disease, arteriovenous fistula and heavy smoking. We report the case of a 49-year-old Asian male with DDA who presented with a painful stellate-shaped purpuric patch on the right thigh. Histopathologic examination showed proliferation of CD34-positive spindle cells in the dermis. Our patient underwent vascular bypass surgery along with tight control of cardiovascular risk factors, which yielded successful results.

Multiple Myeloma Associated GI Polyposis

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 5009-5009
Author(s):  
Nassim Nabbout ◽  
Mohamad El Hawari ◽  
Thomas K. Schulz
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Plasma Cells ◽  
Conflicts Of Interest ◽  
Case Reports ◽  
Bone Marrow Failure ◽  
Bone Lesions ◽  
Rare Manifestation ◽  
History Of ◽  
Central Ulceration

Abstract Abstract 5009 Multiple myeloma is a neoplastic proliferation of monoclonal plasma cells that can result in osteolytic bone lesions, hypercalcemia, renal impairment, bone marrow failure, and the production of monoclonal gammopathy. The gastrointestinal tract is rarely involved in myeloma. GI polyposis is a rare manifestation of extra-medullary disease in multiple myeloma. Such cases usually present as gastrointestinal hemorrhage or intestinal obstruction. A 53-year-old African American male recently diagnosed with multiple myeloma presented with three-day history of rectal bleed and fatigue. EGD showed multiple raised, polypoid, rounded lesions with a superficial central ulceration in the stomach. Colonoscopy showed similar lesions in the ascending and transverse areas of the colon that ranged in size from 5 to 16 mm in diameter. Biopsies showed that these polyps were made of plasma cells. A bone marrow biopsy showed diffuse involvement (greater than 90%) of bone marrow with multiple myeloma with anaplastic features. The patient was started on bortezomib at diagnosis, however, he passed away a few weeks later. This type of metastatic disease has been described in isolated case reports in the literature, while solitary GI plasmacytoma has been reported more frequently. In rare cases, multiple myeloma can involve the GI tract which may lead to bleed or obstruction. This involvement is likely a marker of aggressivity. This example of extra-medullary disease in myeloma is an uncommon variant with features of poor prognosis and dedifferentiation. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Erythematous nodular scalp swellings showing central ulceration and hemorrhagic crusting in an 83-year-old man

2020 ◽  
Vol 11 (2) ◽  
pp. 284
Author(s):  
Ashish Jagati ◽  
RajuG Chaudhary ◽  
SantoshdevP Rathod ◽  
ArwinderKaur Brar
Keyword(s):  
Central Ulceration

The Proliferating and Malignant Proliferating Trichilemmal Cyst: An Anatomo-Clinical Study of Three Cases

2021 ◽  
pp. 1-4
Author(s):  
Ibtissam Benslimane Kamal ◽  
Fouzia Hali ◽  
Farida Marnissi ◽  
Soumiya Chiheb
Keyword(s):  
Clinical Study ◽  
Skin Biopsy ◽  
Clinical Characteristics ◽  
Transitional Form ◽  
Ulcerative Lesion ◽  
The Third ◽  
Trichilemmal Cyst ◽  
Proliferating Trichilemmal Cyst ◽  
Central Ulceration ◽  
Adnexal Tumors

<b><i>Background:</i></b> The proliferating and malignant proliferating trichilemmal cysts (MPTC) are rare adnexal tumors. We report 3 cases through which we will detail the anatomo-clinical characteristics of these tumors. <b><i>Cases:</i></b> Two patients, 60 and 56 years old, consulted for multiple scalp nodules, one of which had changed with the appearance of a central ulceration. The removal of the remaining scalp nodules was in favor of PTCs. The third patient presented with an ulcerative lesion occupying the vertex. Skin biopsy found trichilemmal-type keratinization associated with areas of necrosis concluding with a MPTC. <b><i>Discussion:</i></b> The PTC is a transitional form between the trichilemmal cyst (TC) and the MPTC. The increase in the size of a TC and ulceration are sufficient signals to suspect this evolution.

scholarly journals Atypical piloleiomyoma of the face presenting with central ulceration

2011 ◽  
Vol 3 (3) ◽  
pp. 50 ◽  
Author(s):  
Alessandro Pileri ◽  
Pier Luigi Ghetti ◽  
Iria Neri ◽  
Beatrice Raone ◽  
Selena Ciabatti ◽  
...  
Keyword(s):  
The Face ◽  
Central Ulceration

scholarly journals Cutaneous Rhinosporiodosis in Lower Limb Mimicking Squamous Cell Carcinoma : A Case Report

2020 ◽  
Vol 11 (2) ◽  
pp. 164-166
Author(s):  
Md Mustafizur Rahman ◽  
Nazmun Nahar ◽  
Shah Alam Kiron ◽  
Md Nashir Uddin ◽  
Mst Nusrat Jahan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lower Limb ◽  
Surgical Excision ◽  
Cutaneous Lesions ◽  
Diagnostic Dilemma ◽  
Central Ulceration ◽  
Polypoidal Growth ◽  
The Right

Background: Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidiumseeberi. Though cutaneous lesions in Rhinosporidiosis are rare, they may simulate many common dermatological conditions including malignancy thus posing a diagnostic dilemma. Surgical excision is treatment of choice but dapsone can also be used as an adjunct to surgery. Case Presentation: Here, we are reporting a case where a 45 year old male presented with painless progressive polypoidal growth in the right lower limb for five months with central ulceration. Inguinal lymph nodes were also enlarged. Clinically the lesion appeared to be squamous cell carcinoma. FNAC from inguinal lymph node showed reactive changes and the patient underwent wide local excision of the mass. Histopathological report showed that it was a case of Rhinosporiodosis and the patient was referred to department of dermatology for better management. J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 164-166

Inflammatory Indurated Plaques With Central Ulceration

2021 ◽  
Vol 13 (1) ◽  
pp. 58-60
Author(s):  
Mohsen Baghchechi ◽  
Andre E. Moncrieff ◽  
Sharon E. Jacob
Keyword(s):  
Central Ulceration
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