Children and young people are often trafficked for financial gains as a consequence of trafficking for physical and sexual abuse. The number of such refugees and asylum seekers is almost impossible to determine accurately. Children can be used to smuggle drugs across countries. Although small networks for local crime built around drug dealing, cigarette sales, or the resale of stolen goods use children and young people, there are also highly evolved and structured organizations specializing in drug and sexual trafficking. These challenges require new and different ways of approaching them so that mental health and well-being of children and young people can be maintained. Furthermore, it will be helpful to change the terms of child protection, strengthening structures of support, creating community and street teams with appropriate linguistic competencies, better links between countries of origin and European countries, and better cooperation between police, justice, social workers, and non-governmental organizations. Better approaches are indicated.