The impact of lower body compression garment on left ventricular rotational mechanics in patients with lipedema—Insights from the three‐dimensional speckle tracking echocardiographic
            MAGYAR‐Path
            Study

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. In normal circumstances left ventricular (LV) apex and base rotate different directions during cardiac cycle, while LV apex rotates counterclocwise, LV base has a clockwise movement at the same time. This sort of towel-wringing-like movement is called LV twist. Three-dimensional speckle-tracking echocardiography (3DSTE) is a new, promising, easy-to-perform and reproducible modality for the evaluation of LV apical and basal rotations. Although cardiac adaptation is a known feature seen in highly trained athletes, there are conflicting results according to sport activity-related changes in LV rotational mechanics. The present study was designed to test whether differences in LV rotational mechanics could be detected in elite athletes with high dynamic, but different grade of static components of their training by 3DSTE. Methods. The subjects group comprised 80 elite sportmen, which group of athletes was further divided according to the task force classification of the American College of Cardiology considering dynamic and static components of their training. The following groups were created regarding to their physical activity: Group C1 (high dynamic/low static)(n = 13, mean age: 24.0 ± 5.1 years, Group C2 (high dynamic/moderate static)(n = 23, mean age: 24.6 ± 7.7 years) and Group C3 (high dynamic/high static)(n = 34, mean age: 22.8 ± 6.0 years). Their results were compared to 67 age- and gender-matched non-athletic healthy controls (mean age: 24.0 ± 5.1 years, 33 men). 3DSTE was used for the evaluation of LV rotational abnormalities. Results. Increased LV end-diastolic and end-systolic volumes could be detected in Groups C2 and C3 subjects as compared to controls. No changes in LV volumes and rotational mechanics could be detected in Group C1 cases. Reduced LV basal rotation was seen in Group C2 and C3 subjects compared to that of controls (-3.17 ± 2.81 degree and -2.88 ± 1.88 degree vs. -4.31 ± 1.82 degree, p < 0.05 and p < 0.05, respectively). It was accompanied with LV twist reduction in Groups C2 and C3 subjects compared to that of controls (11.3 ± 4.3 degree and 11.5 ± 4.1 degree vs. 14.0 ± 3.4 degree, p < 0.05 and p < 0.05, respectively). None of elite athletes showed absence of LV twist called as LV ‘rigid body rotation’ (LV-RBR). Conclusions. Significant LV basal rotation and twist reduction could be detected in elite athletes with high dynamic and moderate/high static components of their training.

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The impact of high-normal blood pressure and hypertension on left ventricular function: a three-dimensional speckle tracking echocardiography study

European Heart Journal ◽

10.1093/eurheartj/eht310.p5008 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. P5008-P5008

Author(s):

M. Tadic ◽

V. C. Celic ◽

B. P. Pencic ◽

A. M. Majstorovic ◽

J. S. Suzic ◽

...

Keyword(s):

Blood Pressure ◽

Left Ventricular Function ◽

Ventricular Function ◽

Speckle Tracking ◽

Speckle Tracking Echocardiography ◽

Three Dimensional ◽

Left Ventricular ◽

Normal Blood ◽

Normal Blood Pressure ◽

The Impact

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Left ventricular rotational abnormalities in adult patients with corrected tetralogy of Fallot following different surgical procedures – a three-dimensional speckle-tracking echocardiographic study

European Heart Journal ◽

10.1093/ehjci/ehaa946.2184 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

A Nemes ◽

G Racz ◽

A Kormanyos ◽

P Domsik ◽

A Kalapos ◽

...

Keyword(s):

Tetralogy Of Fallot ◽

Elastic Properties ◽

Speckle Tracking ◽

Aortic Stiffness ◽

Three Dimensional ◽

Left Ventricular ◽

Total Correction ◽

Apical Rotation ◽

Rotational Mechanics ◽

Aortic Elastic Properties

Abstract Introduction Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Abnormal aortic dimensions and elasticity parameters have been long described for corrected TOF (cTOF) together with left ventricular (LV) rotational abnormalities. The present study focuses on investigating LV rotational mechanics in cTOF, and possible correlation of these parameters with aortic elastic properties. It was also aimed to be examined whether different surgical strategies has any effect on the results. Methods The study involved 26 adult cTOF patients, from which 14 had palliative surgery first [Blaloc-Taussig (n=10), Waterstone-Cooley (n=2) shunts, or Brock procedure (n=2)] (mean age at the repair: 7.3±10.2 years) and a late total correction (mean age at the repair: 10.0±13.3 years) (pcTOF), while the early total correction was the treatment of choice in 12 patients (mean age at the repair: 4.2±3.2 years) (etrTOF). Their results were compared to that of 37 age- and gender-matched healthy adults. Routine transthoracic two-dimensional Doppler echocardiography extended with assessment of aortic elastic properties and three-dimensional speckle-tracking echocardiography (3DSTE) was performed in all cTOF patients and controls. Results Sixteen out of 26 cTOF patients showed normally directed LV rotational mechanics, while apical and basal LV rotations were in the same clockwise and counterclockwise directions in 7 and 3 cTOF cases, respectively (38%). This sort of LV movement is called as LV rigid body rotation (RBR). The ratio of LV-RBR between etrTOF and pcTOF patients did not differ significantly (33% vs. 43%, p=0.70). Significantly reduced LV apical rotation (5.2±3.7 degree vs. 10.2±4.5 degree, p<0.05) and twist (9.0±3.3 degree vs. 14.6±4.9 degree, p<0.05) could be demonstrated in cTOF patients with normally directed LV rotational mechanics with preserved LV basal rotation regardless of previous procedure. pcTOF patients showed significantly reduced LV apical rotation as compared to that of etrTOF cases (3.2±3.7 degree vs. 7.1±2.5 degree, p<0.05). From the 7 cTOF patients with clockwise LV-RBR, apical and basal LV rotation proved to be −6.8±5.4 degree and −4.9±2.4 degree, respectively with LV apico-basal gradient of 4.3±3.6 degree. The mean LV apical and basal LV rotation of 3 cTOF patients with counterclockwise LV-RBR prove to be −2.1±3.4 degree and 0.2±0.9 degree, respectively with LV apico-basal gradient of 2.5±2.4 degree. Significant correlations could be demonstrated between LV apical rotation and aortic stiffness index (r=−0.55, p=0.03) and aortic distensibility (r=0.52, p=0.04). Conclusions Significant LV rotational abnormalities could be demonstrated in cTOF with the high prevalence of LV-RBR. cTOF patients with early total reconstruction proved to have beneficial results. Abnormal physiologic response of LV rotational mechanics to increased aortic stiffness can be detected in cTOF patients without LV-RBR. Funding Acknowledgement Type of funding source: None

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Left ventricular apical rotation is associated with mitral annular function in healthy subjects. Results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study

Physiology International ◽

10.1556/2060.2020.00002 ◽

2020 ◽

Vol 107 (1) ◽

pp. 145-154

Author(s):

A. Nemes ◽

Z. Kovács ◽

Á. Kormányos ◽

P. Domsik ◽

A. Kalapos ◽

...

Keyword(s):

Healthy Subjects ◽

Speckle Tracking ◽

Three Dimensional ◽

Left Ventricular ◽

Area Change ◽

Fractional Area Change ◽

Fractional Area ◽

Apical Rotation ◽

Rotational Mechanics ◽

And Function

AbstractIntroductionLeft ventricular (LV) twist is considered an essential part of LV function due to oppositely directed LV basal and apical rotations. Several factors could play a role in determining LV rotational mechanics in normal circumstances. This study aimed to investigate the relationship between LV rotational mechanics and mitral annular (MA) size and function in healthy subjects.MethodsThe study comprised 118 healthy adult volunteers (mean age: 31.5 ± 11.8 years, 50 males). All subjects had undergone complete two-dimensional (2D) Doppler echocardiography and three-dimensional speckle-tracking echocardiography (3DSTE) at the same time by the same echocardiography equipment.ResultsThe normal mean LV apical and basal rotations proved to be 9.57 ± 3.33 and −3.75 ± 1.98°, respectively. LV apical rotation correlated with end-systolic MA diameter, area, perimeter, fractional area change, and fractional shortening, but did not correlate with any end-diastolic mitral annular morphologic parameters. The logistic regression model identified MA fractional area change as an independent predictor of ≤6° left ventricular apical rotation (P < 0.003).ConclusionsCorrelations could be detected between apical LV rotation and end-systolic MA size and function, suggesting relationships between MA dimensions and function and LV rotational mechanics.

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Image Quality Causes Substantial Bias in Three-Dimensional Speckle-Tracking Echocardiography Measures

10.1101/500777 ◽

2018 ◽

Cited By ~ 2

Author(s):

Lamia Al Saikhan ◽

Chloe Park ◽

Alun Hughes

Keyword(s):

Image Quality ◽

Ejection Fraction ◽

Speckle Tracking ◽

Speckle Tracking Echocardiography ◽

Three Dimensional ◽

Poor Quality ◽

Left Ventricular ◽

Systematic Bias ◽

Substantial Bias ◽

The Impact

BACKGROUND: Three-dimensional speckle-tracking echocardiography (3D-STE) is increasingly used to assess left ventricular (LV) mechanics but the quantitative effect of image quality on measurements is not known. OBJECTIVES: To assess the impact of image quality on 3D-STE derived LV indices. METHODS: Echocardiography was performed in two groups of 18 healthy participants. In the first study, optimal and intentionally poor-quality images were acquired. In the second study, a sheet of ultrasound-attenuating material (neoprene rubber) of three different thicknesses (2, 3 and 4 mm) was used to mimic mildly, moderately and severely impaired image quality respectively. RESULTS: In both studies sub-optimal image quality resulted in a systematic underestimation bias in all LV deformation and rotational indices. LV ejection fraction and volumes were also consistently underestimated. The extent of the bias was proportional to the impairment in image quality (i.e. the poorer the image quality the larger the bias). Reproducibility was also less good for sub-optimal images, although LV volumes and ejection fraction showed excellent reproducibility irrespective of image quality. CONCLUSIONS: Sub-optimal image quality introduces a substantial systematic bias and impairs the reproducibility of 3D-STE. Bias related to image quality might have important clinical implications since its magnitude is similar to that reported in association with disease and may confound associations between disease and LV mechanics.

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