Abstract
Background: One of the major challenges of the present century is chronic respiratory failure with a complex, chronic, disabling, and progressive nature, which can gradually affect patient health-related quality of life and their individual and social activities. Therefore, studying its concept will help in recognizing changes in the disease process and predict the status of the disease. This study was prepared to determine health-related quality of life of patients with chronic respiratory failure using a mixed-method approach.Methods and Analysis: The mixed-method approach, with a convergent parallel design, will be used to conduct the research in which the quantitative and qualitative study is performed simultaneously and with the same weight. In the quantitative study section, a cultural and psychometric adaptation of the Severe Respiratory Insufficiency Questionnaire is first translated for patients with severe respiratory failure and then the health-related quality of life dimensions of patients with chronic respiratory failure will be measured using a questionnaire pertaining to the culture of Iranian society in a descriptive-analytical study. Simultaneously with the quantitative study, the researcher will use a qualitative study to explain the perception of patients with chronic respiratory failure and health-related quality of life. Finally, the results of a quantitative study obtained from the analysis of descriptive statistics data (mean and standard deviation) and inferential statistics (analysis of variance, t-test, and regression) are integrated by SPSS software version 18. The results of a qualitative study are the results of conventional content analysis, by comparison and confrontation during interpretation.Discussion & Conclusion: Due to the complexity of the research and for gaining in-depth understanding into the health-related quality of life of patients with chronic respiratory failure, this article will be based on a combination of quantitative and qualitative data. In this research, quantitative and qualitative methods overlap and add to the richness of the data so that the results, beyond the numbers and figures of a quantitative study, will be congruent with an explanation of the concept in a qualitative study and will be discussed and interpreted.
Noninvasive Ventilation in Chronic Respiratory Failure: Effects on Quality of Life
