The effects of home noninvasive ventilation on the quality of life and physiological parameters of patients with chronic respiratory failure

Author(s):  
Aycan Yüksel ◽  
Fatma Çiftçi ◽  
Aydın Çiledağ ◽  
Akın Kaya
Respiration ◽  
2011 ◽  
Vol 81 (5) ◽  
pp. 402-410 ◽  
Author(s):  
Vassiliki Tsolaki ◽  
Chaido Pastaka ◽  
Konstantinos Kostikas ◽  
Eleni Karetsi ◽  
Andreas Dimoulis ◽  
...  

2006 ◽  
Vol 100 (3) ◽  
pp. 477-486 ◽  
Author(s):  
Sara Euteneuer ◽  
Wolfram Windisch ◽  
Stefan Suchi ◽  
Dieter Köhler ◽  
Paul W. Jones ◽  
...  

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Luca Valko ◽  
Szabolcs Baglyas ◽  
Laszlo Kunos ◽  
Attila Terray-Horvath ◽  
Andras Lorx ◽  
...  

Abstract Background Home mechanical ventilation is a reliable treatment for patients suffering from chronic respiratory failure, improving survival and quality of life. Prevalence has been increasing worldwide as a result of evolving technical possibilities, telemedicine and improving national guidelines. Projects to establish a national guideline and registry for patients treated with home mechanical ventilation are currently under way in Hungary and our aim was to validate a quality of life questionnaire suited for evaluation and follow up in this specific patient group. The Severe Respiratory Insufficiency Questionnaire (SRI) is a quality of life tool designed to evaluate patients receiving home mechanical ventilation and has been validated both in patient groups receiving invasive and noninvasive ventilation. Methods The Hungarian version of the SRI was created using the translation-backtranslation method, which was then tested for validity, viability and reliability in a cohort involving patients from three centers, receiving long-term home mechanical ventilation for chronic respiratory failure through an invasive or noninvasive interface. Patient data was collected (demographic data, lung function test, arterial blood gas, ventilation settings) and quality of life was measured with the previously validated SF-36 and newly created Hungarian SRI Questionnaires at two time points. Results One hundred four patients receiving home mechanical ventilation were enrolled. The time to complete the SRI Questionnaire was 8.6 (±3.1) minutes, 69.2% questionnaires were self-administered. Exploratory factor analysis explained 73.8% of the variance of the questionnaire, but resulted in 13 scales. We found correlations between the SRI subscale scores to corresponding scales of the previously validated general quality of life survey SF-36. The Cronbach alpha coefficient was 0.928 for the Summary Scale of the SRI Questionnaire, proving high internal consistency. Reproducibility was high for most scales, resulting in a high overall correlation for the summary score (0.877, p < 0.001). Conclusions The Hungarian version of the SRI Questionnaire is a viable, valid, reliable and reproduceable quality of life tool applicable for patients treated with home mechanical ventilation.


2000 ◽  
Vol 12 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Koji Usui ◽  
Kazuyuki Tabira ◽  
Noriko Sekikawa ◽  
Osamu Yoshimura ◽  
Hiroshi Maejima ◽  
...  

2008 ◽  
Vol 32 (2) ◽  
pp. 379-386 ◽  
Author(s):  
M. L. Duiverman ◽  
J. B. Wempe ◽  
G. Bladder ◽  
H. A. M. Kerstjens ◽  
P. J. Wijkstra

2020 ◽  
Author(s):  
Elyas HosseinzadeH Younesi ◽  
Zahra Sabzi ◽  
Leila Teymouri Yeganeh ◽  
Shohreh Kolagari

Abstract Background: One of the major challenges of the present century is chronic respiratory failure with a complex, chronic, disabling, and progressive nature, which can gradually affect patient health-related quality of life and their individual and social activities. Therefore, studying its concept will help in recognizing changes in the disease process and predict the status of the disease. This study was prepared to determine health-related quality of life of patients with chronic respiratory failure using a mixed-method approach.Methods and Analysis: The mixed-method approach, with a convergent parallel design, will be used to conduct the research in which the quantitative and qualitative study is performed simultaneously and with the same weight. In the quantitative study section, a cultural and psychometric adaptation of the Severe Respiratory Insufficiency Questionnaire is first translated for patients with severe respiratory failure and then the health-related quality of life dimensions of patients with chronic respiratory failure will be measured using a questionnaire pertaining to the culture of Iranian society in a descriptive-analytical study. Simultaneously with the quantitative study, the researcher will use a qualitative study to explain the perception of patients with chronic respiratory failure and health-related quality of life. Finally, the results of a quantitative study obtained from the analysis of descriptive statistics data (mean and standard deviation) and inferential statistics (analysis of variance, t-test, and regression) are integrated by SPSS software version 18. The results of a qualitative study are the results of conventional content analysis, by comparison and confrontation during interpretation.Discussion & Conclusion: Due to the complexity of the research and for gaining in-depth understanding into the health-related quality of life of patients with chronic respiratory failure, this article will be based on a combination of quantitative and qualitative data. In this research, quantitative and qualitative methods overlap and add to the richness of the data so that the results, beyond the numbers and figures of a quantitative study, will be congruent with an explanation of the concept in a qualitative study and will be discussed and interpreted.


2013 ◽  
Vol 8 ◽  
Author(s):  
Stefano Marinari ◽  
Maria Rosaria Manigrasso ◽  
Fernando De Benedetto

Background: The protein-calorie malnutrition, resulting in muscle mass loss, frequently occurs in severe COPD patients with chronic respiratory failure (CRF), causing dyspnea, reduced exercise tolerance and impaired quality of life. The cause of this occurrence is an intake-output energy imbalance. A documented deficit of phosphocreatine and reduced mithocondrial energy production can contribute to this imbalance. Aim of this study is to verify whether a dietary supplementation with creatine and coenzyme Q10, important mitochondrial function factors, is able to influence this mechanism leading to a dyspnea reduction and improving exercise tolerance and quality of life. Methods: 55 COPD patients with chronic respiratory failure (in long term O2 therapy), in stable phase of the disease and without severe comorbidities were assigned (double-blind, randomized) to: group A (30 patients) with daily dietary supplementation with Creatine 340 mg + 320 mg Coenzyme Q-Ter (Eufortyn®, Scharper Therapeutics Srl) for 2 months whereas Group B (25 patients) received placebo. All patients continued the same diet, rehabilitation and therapy during the study. At recruitment (T0) and after 2 months (T1), patients were submitted to medical history, anthropometry (BMI), bioelectrical impedance, arterial blood gas analysis, evaluation of dyspnea (VAS, Borg, BDI, MRC) and functional independence (ADL), 6-minute walk test (6MWT) and quality of life questionnaire (SGRQ). At 6 months and 1 year, a telephone follow up was conducted on exacerbations number. Results: No significant difference was detected at baseline (T0) in the 2 groups. After 2 months of therapy (T1) the FFMI increased in the daily dietary supplementation group (+ 3.7 %) and decreased in the placebo group (− 0.6 %), resulting in a statistically significant (p < 0.001) treatment difference. Statistically significant treatment differences, favouring daily dietary supplementation group, were also seen for the 6MWT comparison. Group A patients also showed significant: 1) improvement in the degree of dyspnea (VAS: p < 0.05; Borg: p < 0.05; MRC: p < 0.001; BDI1: p < 0.05; BDI3: p < 0.03), and independence level in activities of daily living (p < 0.03); 2) improvement in quality of life in activity section (− 6.63 pt) and in total score (− 5.43 pt); 3) exacerbation number decrease (p < 0.02). No significant differences were found (end of study vs baseline) in group B. Conclusions: The nutraceutical diet integration with Q-Ter and creatine, in COPD patients with CRF in O2TLT induced an increasing lean body mass and exercise tolerance, reducing dyspnea, quality of life and exacerbations. These results provide a first demonstration that acting on protein synthesis and muscular efficiency can significantly modify the systemic consequences of the disease.


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