Effect of alcohol prohibition on liver cirrhosis mortality rates in Canada from 1901 to 1956: A time‐series analysis

Background. Hypertension (HTN) is reported to be the leading contributor to premature death globally. Considerable research evidence suggests that excessive alcohol intake (binge drinking) is an independent risk factor for HTN. It was repeatedly emphasized that binge drinking is a major contributor to a high cardiovascular mortality rate in Russia.Objective. The aim of this study was to examine the aggregate-level relation between alcohol consumption and HTN mortality rates in Russia.Method. Age-standardized sex-specific male and female HTN mortality data for the period 1980–2005 and data on overall alcohol consumption were analyzed by means of ARIMA (autoregressive integrated moving average) time-series analysis. The level of alcohol consumption per capita has been estimated using the indirect method based on alcohol psychoses incidence rate and employing ARIMA time-series analysis.Results. Alcohol consumption was significantly associated with both male and female HTN mortality rates: a 1-liter increase in overall alcohol consumption would result in a 6.3% increase in the male HTN mortality rate and in a 4.9% increase in female HTN mortality rate. The results of the analysis suggest that 57.5% of all male HTN deaths and 48.6% of all female HTN deaths in Russia could be attributed to alcohol.Conclusions. The outcomes of this study provide support for the hypothesis that alcohol is an important contributor to the high HTN mortality rate in the Russian Federation. The findings from the present study have important implications with to regards HTN mortality prevention, indicating that a restrictive alcohol policy can be considered as an effective measure of prevention in countries with a higher rate of alcohol consumption.

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Reduction of maternal mortality due to preeclampsia in Colombia-an interrupted time-series analysis

Colombia Medica ◽

10.25100/cm.v45i1.1466 ◽

2014 ◽

pp. 25-31 ◽

Cited By ~ 7

Author(s):

Julian Alberto Herrera Herrera ◽

Rodolfo Herrera-Miranda ◽

Juan Pablo Herrera-Escobar ◽

Aníbal Nieto-Díaz

Keyword(s):

Time Series ◽

Prenatal Care ◽

Time Series Analysis ◽

Maternal Mortality ◽

Care Program ◽

Interrupted Time Series ◽

Mortality Rates ◽

Interrupted Time Series Analysis ◽

Series Analysis ◽

The Impact

Introduction. Preeclampsia is the most important cause of maternal mortality in developing countries. A comprehensive prenatal care program including bio-psychosocial components was developed and introduced at a national level in Colombia. We report on the trends in maternal mortality rates and their related causes before and after implementation of this program. Methods: General and specific maternal mortality rates were monitored for nine years (1998-2006). An interrupted time-series analysis was performed with monthly data on cases of maternal mortality that compared trends and changes in national mortality rates and the impact of these changes attributable to the introduction of a bio-psychosocial model. Multivariate analyses were performed to evaluate correlations between the interventions. Results: Five years after (2002–2006) its introduction the general maternal mortality rate was significantly reduced to 23% (OR= 0.77, CI 95% 0.71-0.82).The implementation of BPSM also reduced the incidence of preeclampsia in 22% (OR= 0.78, CI 95% 0.67-0.88), as also the labor complications by hemorrhage in 25% (OR= 0.75, CI 95% 0.59-0.90) associated with the implementation of red code. The other causes of maternal mortality did not reveal significant changes. Biomedical, nutritional, psychosocial assessments, and other individual interventions in prenatal care were not correlated to maternal mortality (p= 0.112); however, together as a model we observed a significant association (p= 0.042). Conclusions: General maternal mortality was reduced after the implementation of a comprehensive national prenatal care program. Is important the evaluation of this program in others populations.

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Effect of alcoholism treatment on cirrhosis mortality: a 20-year multivariate time series analysis

Addiction ◽

10.1111/j.1360-0443.1992.tb02735.x ◽

1992 ◽

Vol 87 (9) ◽

pp. 1263-1274 ◽

Cited By ~ 46

Author(s):

HAROLD D. HOLDER ◽

ROBERT NASH PARKER

Keyword(s):

Time Series ◽

Time Series Analysis ◽

Multivariate Time Series ◽

Alcoholism Treatment ◽

Series Analysis ◽

Multivariate Time Series Analysis ◽

Cirrhosis Mortality

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The impact of increasing the minimum legal drinking age to 20 years in Lithuania on all-cause mortality- an interrupted time-series analysis

10.1101/2021.04.07.21255080 ◽

2021 ◽

Author(s):

Alexander Tran ◽

Huan Jiang ◽

Shannon Lange ◽

Michael Livingston ◽

Jakob Manthey ◽

...

Keyword(s):

Time Series ◽

Young Adults ◽

Time Series Analysis ◽

Interrupted Time Series ◽

Mortality Rates ◽

Interrupted Time Series Analysis ◽

Series Analysis ◽

All Cause Mortality ◽

Drinking Age ◽

Minimum Legal Drinking Age

Aims: To determine the effect of an alcohol policy change, which increased the minimum legal drinking age (MLDA) from 18 years of age to 20 years of age on all-cause mortality rates in young adults in Lithuania. Methods: An interrupted time series analysis was conducted on a dataset from 2001 to 2019 (n = 228 months). The model tested the effects of the MLDA on all-cause mortality rates (deaths per 100,000 individuals) in 3 age categories (15-17 years old, 18-19 years old, 20-22 years old). Additional models that included GDP as a covariate and taxation policy were tested as well. Results: There was a significant effect of the MLDA on all-cause mortality rates in those 18-19 years old, when modelled alone. Additional analyses controlling for the mortality rate of other age groups showed similar findings. Inclusion of confounding factors (policies on alcohol taxation, GDP) eliminated the effects of MLDA. Conclusions: Although there was a notable decline in all-cause mortality rates among young adults in Lithuania, a direct causal impact of MLDA on all-cause mortality rates in young adults was not definitively found.

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TENDENCIES OF THE MORTALITY RATES FROM ESOPHAGEAL CANCER IN THE EU COUNTRIES AND UKRAINE

Kharkiv Surgical School ◽

10.37699/2308-7005.2.2020.21 ◽

2020 ◽

pp. 102-107

Author(s):

Nadiya Dubrovina ◽

Ivica Gulášová ◽

Jozef Babečka

Keyword(s):

Time Series ◽

Esophageal Cancer ◽

Health Status ◽

Time Series Analysis ◽

Mortality Rates ◽

Demographic Characteristics ◽

General Health Status ◽

Eu Countries ◽

Series Analysis ◽

The Eu

Summary. In this article the problems of the prevalence of esophageal cancer and the distribution of mortality rates from this disease are considered in EU countries. The rates of mortality from esophageal cancer are analyzed by statistical methods and time series analysis. A study is carried out of the features of the tendencies of mortality rates from esophageal cancer in six EU countries and in Ukraine. It is emphasized that various factors, such as the environmental situation, socio-demographic characteristics of the population, culture and nature of nutrition, the general health status of the population, the availability of resources and the level of healthcare in the region should be took into account for development of the programmes for the prevention of prevalence of esophageal cancer. By means of the models for time series analysis we forecast the rates of mortality from esophageal cancer for six countries of EU and for Ukraine, which can be used for the development of the national strategies to reduce the prevalence and mortality from esophageal cancer.

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