Clinical Case Conundrum: Hyperlactataemia in a Case of Type 1 Diabetes with Chronic Hyperglycaemia

2021 ◽  
Author(s):  
Talia A. Hitt ◽  
Joshua Eisenberg ◽  
Lea F. Surrey ◽  
Ami Gokli ◽  
Edisio Semeao ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Clinical Case ◽  
Chronic Hyperglycaemia

Two types diabetes mellitus: clinical case of HNF1B–mody and type 1 diabetes in one patient

2020 ◽  
Author(s):  
Alla Ovsyannikova ◽  
Oksana Rymar ◽  
Elena Shakhtshneider ◽  
Mikhail Voevoda
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Clinical Case

scholarly journals Hepatomegaly and type 1 diabetes: a clinical case of Mauriac’s syndrome

2019 ◽  
Vol 45 (1) ◽  
Author(s):  
Fortunato Lombardo ◽  
Stefano Passanisi ◽  
Albino Gasbarro ◽  
Giovanni Tuccari ◽  
Antonio Ieni ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Clinical Case

scholarly journals Celiac disease in a patient with type 1 diabetes

2020 ◽  
pp. 107-112
Author(s):  
M. A. Livzan ◽  
O. V. Gaus ◽  
M. V. Kolbina ◽  
F. Zh. Karasaeva ◽  
O. A. Ratnikova
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Autoimmune Diseases ◽  
Clinical Case ◽  
Rapid Development ◽  
Epidemiological Studies ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Genetic And Environmental Factors

The interaction of genetic and environmental factors leads to development of autoimmune diseases. Autoimmune diseases have common pathogenetic mechanisms and are combined often. in recent years Epidemiological studies have shown a significant increase in the prevalence of celiac disease in patients with type 1 diabetes mellitus (T1DM) in recent years. Comorbid pathology is a heavy clinical case to determine the treatment of patients. The association of celiac disease and T1DM leads to enhanced immune response and rapid development and progression of complications. A gluten-free diet is only treatment for celiac disease. Gluten-free diet complicates glycemic control. This article presents our clinical case of a patient with combination of celiac disease and T1DM.

scholarly journals Sugar Rush - Type 1 Diabetes Mellitus and Deliberate Self-Injury A Clinical Case Report

2019 ◽  
Author(s):  
Ana Pinho ◽  
Ana Amorim ◽  
Hugo Bastos ◽  
Maria do Carmo Cruz
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Case Report ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Case ◽  
Self Injury

scholarly journals Modern technology for the treatment of type 1 diabetes mellitus with end-stage renal failure

2015 ◽  
Vol 18 (2) ◽  
pp. 89-95
Author(s):  
Yulia Alexandrovna Krupinova ◽  
Sergei Andreevich Martinov ◽  
Alexandra Michailovna Glazunova ◽  
Evgeny Vladimirovich Tarasov
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Type 1 Diabetes ◽  
Kidney Transplantation ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Case ◽  
Modern Technology ◽  
End Stage Renal Failure ◽  
End Stage

This article describes the clinical case of a patient with early development of terminal complications of type 1 diabetes with chronic decompensated carbohydrate metabolism. For 1 year, the patient was treated with hemodialysis and she subsequently underwent successful kidney transplantation.

Clinical case of type 1 diabetes mellitus and multiple sclerosis - just bad luck?

2014 ◽  
Author(s):  
Ana Wessling ◽  
Jose Maria Aragues ◽  
Silvia Guerra ◽  
Mario Mascarenhas
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Case

scholarly journals Current and future therapies for type 1 diabetes

Diabetologia ◽  
2021 ◽  
Vol 64 (5) ◽  
pp. 1037-1048 ◽  
Author(s):  
Bernt Johan von Scholten ◽  
Frederik F. Kreiner ◽  
Stephen C. L. Gough ◽  
Matthias von Herrath
Keyword(s):  
Type 1 Diabetes ◽  
Beta Cell ◽  
Management Strategies ◽  
Stress Factors ◽  
Immune Mediated ◽  
Pancreatic Islets Of Langerhans ◽  
Glucagon Like Peptide 1 ◽  
Chronic Hyperglycaemia ◽  
Number Of Individuals

AbstractIn type 1 diabetes, insulin remains the mature therapeutic cornerstone; yet, the increasing number of individuals developing type 1 diabetes (predominantly children and adolescents) still face severe complications. Fortunately, our understanding of type 1 diabetes is continuously being refined, allowing for refocused development of novel prevention and management strategies. Hitherto, attempts based on immune suppression and modulation have been only partly successful in preventing the key pathophysiological feature in type 1 diabetes: the immune-mediated derangement or destruction of beta cells in the pancreatic islets of Langerhans, leading to low or absent insulin secretion and chronic hyperglycaemia. Evidence now warrants a focus on the beta cell itself and how to avoid its dysfunction, which is putatively caused by cytokine-driven inflammation and other stress factors, leading to low insulin-secretory capacity, autoantigen presentation and immune-mediated destruction. Correspondingly, beta cell rescue strategies are being pursued, which include antigen vaccination using, for example, oral insulin or peptides, as well as agents with suggested benefits on beta cell stress, such as verapamil and glucagon-like peptide-1 receptor agonists. Whilst autoimmune-focused prevention approaches are central in type 1 diabetes and will be a requirement in the advent of stem cell-based replacement therapies, managing the primarily cardiometabolic complications of established type 1 diabetes is equally essential. In this review, we outline selected recent and suggested future attempts to address the evolving profile of the person with type 1 diabetes. Graphical abstract

scholarly journals Clinical case of type 1 diabetes mellitus combined with Graves’ disease and epilepsy

2019 ◽  
pp. 108-111
Author(s):  
E. N. Smirnova ◽  
T. P. Demicheva
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Case ◽  
Graves Disease

scholarly journals ACTRAPID AND PROTAPHANE ALLERGY: RECURRENT URTICARIA, ANGIOEDEMA. CLINICAL CASE

2017 ◽  
Vol 14 (6) ◽  
pp. 36-42
Author(s):  
A S Prylutski ◽  
O A Prylutskaya ◽  
E S Polkovnik
Keyword(s):  
Type 1 Diabetes ◽  
Side Effects ◽  
Allergic Reaction ◽  
Clinical Case ◽  
Clinical Effect ◽  
Insulin Analogues ◽  
Genetically Engineered ◽  
Patients With Diabetes

The increasing number of the patients with diabetes who use insulin for treatment makes the study of side effects to the above mentioned medicines important and relevant. Due to the current use of human genetically engineered insulin analogues, complications caused by their use develop less often. We described the case of an allergic reaction to the аctrapid and рrotaphane in a patient with Type 1 Diabetes manifested in the form of chronic, recurrent urticaria and angioedema. Sensitization to the above mentioned insulin preparations was proved clinically and with specific immunoallergological methods. The replacement of insulin preparations caused a stable clinical effect.

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