The diagnostic value of p63, p16, and p53 immunohistochemistry in distinguishing seborrheic keratosis, actinic keratosis, and Bowen's disease

2021 ◽  
Author(s):  
Soheila Nasiri ◽  
Vahidehsadat Azhari ◽  
Farahnaz Bidari‐Zerehpoosh ◽  
Zahra Asadi‐Kani ◽  
Atefeh Talebi
2011 ◽  
Vol 73 (3) ◽  
pp. 260-265
Author(s):  
Toshinori BITO ◽  
Shun OHMORI ◽  
Mayuko YOSHIZAWA ◽  
Sanehito HARUYAMA ◽  
Yu SAWADA ◽  
...  

Author(s):  
Daniel Holanda Daniel

A variety of cutaneous lesions can mimic melanoma, such as melanocytic nevi, lentigines, seborrheic keratosis, blue nevi, pigmented basal cell carcinomas and dermatofibromas. This report describes a rare clinical case of a female patient who presented a lesion on the left thigh, which was clinically and dermoscopically compatible with melanoma. The patient underwent excision of the lesion, and histopathology confirmed a diagnosis of pigmented Bowen’s disease. The purpose of this report is to draw attention to the fact that pigmented Bowen’s disease, a rare form of squamous cell carcinoma in situ, should also be considered as a differential diagnosis of malignant melanoma.  


2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Takayuki Inoue ◽  
Ken Kobayashi ◽  
Mizuki Sawada ◽  
Sumiko Ishizaki ◽  
Haruo Ito ◽  
...  

Various structures have been reported for dermoscopic features of pigmented Bowen's disease (BD), which could be a mimic of various pigmented skin lesions. A 79-year-old Japanese woman presented with a 3-year history of brown-black macule on her right upper arm without symptom. Dermoscopic examination demonstrated irregular flossy streaks, irregular brown dots/globules, blue-whitish regression structures, and overlaying whitish scaly areas. We suspected pigmented skin lesions including seborrheic keratosis, pigmented eccrine poroma, and malignant melanoma and excised completely with a 5 mm margin. Histopathological features were consistent with a diagnosis of pigmented BD. Although similar dermoscopic features might be revealed in pigmented skin lesions and it may occasionally be difficult to distinguish between pigmented BD and other pigmented skin lesions, dermoscopy would be useful in speculating pathologic features of pigmented BD.


2014 ◽  
Vol 41 (9) ◽  
pp. 863-864 ◽  
Author(s):  
Satoko Minakawa ◽  
Takahide Kaneko ◽  
Yasushi Matsuzaki ◽  
Eijiro Akasaka ◽  
Hiroki Mizukami ◽  
...  

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