Global myocardial work: A new way to detect subclinical myocardial dysfunction with normal left ventricle ejection fraction in essential hypertension patients: Compared with myocardial layer‐specific strain analysis

2021 ◽  
Author(s):  
Jun Huang ◽  
Chao Yang ◽  
Zi‐Ning Yan ◽  
Li Fan ◽  
Cai‐Fang Ni
2021 ◽  
Author(s):  
Tao Wang ◽  
Jun Huang ◽  
Zi-ning Yan ◽  
Li Fan

Abstract To assess the subclinical left ventricle(LV) myocardial dysfunction in preserved left ventricle ejection fraction(LVEF) in type 2 diabetes mellitus(T2DM) patients by global myocardial work(MW). 60 untreated T2DM patients and 60 normal controls were enrolled for this study. Apical 4-, 3- and 2- chamber views were acquired by two-dimensional echocardiography. Peak systolic myocardial layer-specific global longitudinal strain(GLS), peak strain dispersion(PSD), global myocardial work index(GWI), global constructive work(GCW), global wasted work(GWW), and myocardial work efficiency(GWE) were generated by speckle-tracking echocardiography(STE). The values of GLS in T2DM patients were significantly lower than normal controls(p < 0.05). GWW in T2DM patients was significantly larger than normal controls, while GWE was significantly lower(p < 0.05). In T2DM patients, fasting plasma glucose positively correlated with GWW, while negatively correlated with GWE, respectively. ROC analysis showed GWE was superior to other values with a highest AUC of 0.688. Logistic regression analysis indicated that GLSEndo (OR = 1.196, 95% CI: 1.012–1.414, p = 0.036), and GWE (OR = 0.585, 95% CI: 0.414–0.825, p = 0.002) were independent risk factors associated with LV function in T2DM patients. From the research, the subclinical LV myocardial dysfunction was detected by GLS and global MW in T2DM patients. Global MW is a sensitive predictor to demonstrate the subclinical LV myocardial dysfunction in T2DM patients.


Renal Failure ◽  
2016 ◽  
Vol 38 (10) ◽  
pp. 1622-1625 ◽  
Author(s):  
Faruk Ozkul ◽  
Muhammmet Kasim Arik ◽  
Halil Erbiş ◽  
Alpaslan Akbaş ◽  
Vural Taner Yilmaz ◽  
...  

Author(s):  
F. Contorni ◽  
M. Fineschi ◽  
A. Iadanza ◽  
A. Santoro ◽  
G. E. Mandoli ◽  
...  

AbstractLow-flow low-gradient aortic stenosis (LFLG AS) with reduced left ventricle ejection fraction (LVEF) is still a diagnostic and therapeutic challenge. The aim of this paper is to review the latest evidences about the assessment of the valvular disease, usually difficult because of the low-flow status, and the therapeutic options. Special emphasis is given to the available diagnostic tools for the characterization of LFLG AS without functional reserve at stress echocardiography and to the factors that clinicians should evaluate to choose between surgical aortic valve repair, transcatheter aortic valve implantation, or medical therapy.


Author(s):  
Ahmad Amin ◽  
Seyed Parsa Eftekhar ◽  
Naghmeh Ziaei ◽  
Soudeh Roudbari ◽  
Pegah Salehi ◽  
...  

We described eleven patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The younger age and female gender seem to contribute to poor outcomes possibly. Furthermore, the left ventricle ejection fraction and pro-BNP improvement within the first week of treatment might indicate a good prognosis.


2020 ◽  
Vol 20 (1) ◽  
pp. 308-313
Author(s):  
Bhooma Vijayaraghavan ◽  
Giri Padmanabhan ◽  
Kumaresan Ramanathan

Background: Left ventricular hypertrophy (LVH) has been proved as one among the cardiovascular complications and pre- dominant in patients with CKD. In CKD patients, Glycated albumin (GA) express a superior marker of glycemic control than HbA1c. Nevertheless, the precision of GA for the prediction of cardiovascular diseases among the CKD population has been ineffectively reported. The present study looks at the part of GA, HbA1c in CKD to envisage vascular complications. Materials and methods: One hundred and ninety-four patients were selected in the present study. The study has a control group (Group I, N: 52) and participants were divided into two groups based on vein diseases (Group II, N: 42; two vessels and group III, N: 100; triple vessel disease). Serum glycated albumin, hsCRP and other routine parameters were estimated in all the three groups. 2-dimensional echocardiography (2D Echo) has been done by a cardiologist to all the study patients for assessing ejection fraction and distinguish the sort of vessel diseases. Results: Group I compared with group II and III shown there was a significant association among blood glucose, serum creati- nine, HbA1c, mean blood glucose, GA, ejection fraction and hsCRP. Additionally, observed that increased levels of HbA1c, GA and creatinine inversely related to the left ventricle ejection fraction. Notwithstanding, GA and hsCRP predict precisely the left ventricle ejection fraction than different parameters. Conclusion: GA alongside hsCRP might be appropriate markers for anticipating cardiovascular diseases particularly left ventricle hypertrophy in diabetic CKD population. Keywords: CKD; glycemic control; Left Ventricular Hypertrophy; GA; HbA1c. 


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