Linear decline of corrected platelet count increment within 24 hours after platelet transfusion in haematological patients: A prospective observational study

2017 ◽  
Vol 99 (6) ◽  
pp. 559-568 ◽  
Author(s):  
Sigurdur Benediktsson ◽  
Vladimir Lazarevic ◽  
Lars Nilsson ◽  
Jens Kjeldsen-Kragh ◽  
Ulf Schött ◽  
...  
Keyword(s):  
Platelet Count ◽  
Observational Study ◽  
Platelet Transfusion ◽  
Prospective Observational Study ◽  
Haematological Patients ◽  
Linear Decline

scholarly journals Immune Thrombocytopenic Purpura in Pregnancy- A Prospective Observational Study in a Tertiary Care Centre

2019 ◽  
Vol 34 (1) ◽  
pp. 15-21
Author(s):  
Tabassum Parveen ◽  
Firoza Begum ◽  
Nahreen Akhter ◽  
Nigar Sultana ◽  
Khairun Nahar
Keyword(s):  
Platelet Count ◽  
High Risk ◽  
Observational Study ◽  
Immune Thrombocytopenic Purpura ◽  
Platelet Transfusion ◽  
Prospective Observational Study ◽  
Thrombocytopenic Purpura ◽  
Neonatal Thrombocytopenia ◽  
Itp In Pregnancy ◽  
In Pregnancy

Objectives: Immune thrombocytopenic purpura (ITP) in pregnancy necessitates management of two patients, the mother and the newborn. Complications like maternal bleeding, fetal and neonatal thrombocytopenia demands appropriate and timely therapy. This prospective observational study was designed to explore and summarize the current approach to the investigation, diagnosis, management and outcome of ITP in pregnancy. Materials and Methods: Women with ITP admitted in the Fetomaternal Medicine Department of Bangabandhu Sheikh Mujib Medical University (BSMMU) from 2009 -2017, were included in the study. Total number of high risk pregnancy during that period were 7704 among them 20 cases were pregnancy with Immune Thrombocytopenic Purpura (ITP). Patients were managed under joint supervision of the fetomaternal medicine specialist and the hematologist. Prednisolone was considered as a first line drug in management protocol. Platelet transfusion was considered if there were symptoms or count <20X109/L at any stage of pregnancy or <50 X109 / L in late pregnancy without symptoms. Platelet count of newborn was performed at birth and repeated on day four and count<150X109/L was considered as neonatal thrombocytopenia. Results: Frequency of ITP among high risk patients was found 2.5/1000 live birth, most were preexisting (75%). Almost all cases (95%) were treated with prednisolone. Commonest clinical presentations were gum bleeding (70 %) and purpuric rashes (60%). Though during pregnancy, severe thrombocytopenia (<50 X109/L) was found in 7 patients (35%) but none was at the time of delivery, as drugs and/or platelet transfusion was considered to make delivery process safe. Platelet transfusion needed in 77.7% cases in a range of 1-75 units. Primary PPH noted in 3 cases (17%), increased bleeding during surgery in 5 patients (33%) and one patient needed ICU support. Neonatal thrombocytopenia noted in 5 cases (28%). Though 2 of the neonates needed NICU admission but none needed platelet transfusion and all the babies were discharged healthy. Conclusion: This study documents that pregnancy with ITP need close monitoring, require agents to raise the platelet count and repeated platelet transfusion to maintain reasonable safe platelet count. There are chances of PPH, capillary oozing during surgery. However good outcome is possible for most women, fetus and neonates with appropriate and timely therapy. Bangladesh J Obstet Gynaecol, 2019; Vol. 34(1): 15-21

Prospective observational study of low thresholds for platelet transfusion in adult dengue patients

Transfusion ◽  
2009 ◽  
Vol 49 (7) ◽  
pp. 1400-1411 ◽  
Author(s):  
Laurent Thomas ◽  
Stéphane Kaidomar ◽  
Brigitte Kerob-Bauchet ◽  
Victor Moravie ◽  
Yannick Brouste ◽  
...  
Keyword(s):  
Observational Study ◽  
Platelet Transfusion ◽  
Prospective Observational Study

An observational study to see the correlation between trends of platelet counts and immature platelet fraction in dengue infection

2021 ◽  
pp. 004947552110170
Author(s):  
Darshit Shah ◽  
Mridusmita Khataniar ◽  
Aanchal Sawhney ◽  
Manishi Nautiyal ◽  
Rishikesh Desai ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Platelet Count ◽  
Blood Transfusion ◽  
Observational Study ◽  
Low Income ◽  
Strong Correlation ◽  
Platelet Transfusion ◽  
Dengue Infection ◽  
Viral Disease ◽  
Immature Platelet Fraction

Dengue, a common tropical viral disease, often has complications of thrombocytopenia causing bleeding and warranting blood transfusion. This is costly in low-income settings. We conducted an observational study using a relatively new parameter called immature platelet fraction which indicates regeneration of platelets by the bone marrow. Our study on 124 dengue patients showed a strong correlation between platelet count and immature platelet fraction and we observed that 96.1% and 97.4% patients showed rise in platelet count at 24 and 48 h, respectively. In the absence of bleeding, platelet transfusion was prevented in 64% of patients with an IPF level of 10% or more.

scholarly journals A PROSPECTIVE OBSERVATIONAL STUDY FOR RELATIONSHIP BETWEEN THROMBOCYTOPENIA AND CULTURE POSITIVE NEONATAL BACTERIAL SEPSIS

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Anita Devi ◽  
Rakesh Kumar Sharma ◽  
Kapil Kumar
Keyword(s):  
Platelet Count ◽  
Observational Study ◽  
Neonatal Sepsis ◽  
Prospective Observational Study ◽  
Hematological Parameters ◽  
Clinical Signs ◽  
Sepsis Group ◽  
P Value ◽  
Distribution Width ◽  
Platelet Indices

Background: Changes in Platelet parameters like Mean Platelet Volume and Platelet Distribution Width are helpful in diagnosis of neonatal sepsis but these indices have not been extensively studied in neonatal sepsis. Hence, the present study is undertaken to evaluate Platelet count and platelet indices in diagnosis of neonatal sepsis. Methods: This prospective observational study was conducted over a period of 4 months i.e from December 2019 to March 2020 in neonatal intensive care unit of Jhalawar Medical College & Attached Hospitals, Jhalawar. During the study period 154 consecutive neonates (both inborn and out born), with clinical signs and symptoms of sepsis along with either positive culture (confirmed neonatal sepsis ) or other laboratory findings suggestive of bacterial and fungal infection in absence of positive cultures (probable sepsis), were included after written informed consent from parents. Results: Out of total (154), 81.8%, 76% and 67.5% of cases had thrombocytopenia, raised MPV (>10.8) and raised PDW respectively. As compared to Non-sepsis group, MPV values were raised in more cases of Sepsis proven group (88%) and the difference was statistically significant with P value of 0.011. PDW values were also more increased in Sepsis proven group compared to Non-sepsis group. Conclusion: Platelet count and platelet indices, which are easily available hematological parameters in remote & resource poor areas of our country, should be taken into consideration for suspected cases of neonatal sepsis so that prompt treatment can be given, and morbidity and mortality can be reduced. Keywords: Sepsis, CRP, MPV, PDW.

scholarly journals Platelet count and function in paediatric cardiac surgery: a prospective observational study

2014 ◽  
Vol 113 (5) ◽  
pp. 847-854 ◽  
Author(s):  
B.S. Romlin ◽  
F. Söderlund ◽  
H. Wåhlander ◽  
B. Nilsson ◽  
F. Baghaei ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Platelet Count ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Paediatric Cardiac Surgery ◽  
And Function

scholarly journals Diagnostic value of ferritin for the severity of dengue infection in children

2019 ◽  
Vol 12 (3) ◽  
pp. 146-149
Author(s):  
Farzana Ahmed ◽  
Nargis Ara Begum ◽  
Md.  Moshiur Rahman ◽  
Md.  Salim Shakur ◽  
Shabrina Sharmin
Keyword(s):  
Platelet Count ◽  
Observational Study ◽  
Dengue Fever ◽  
Serum Ferritin ◽  
Prospective Observational Study ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Dengue Infection ◽  
Diagnostic Value ◽  
Hematocrit Level

The study was conducted to evaluate whether the severity of dengue fever can be predicted by serum ferritin level or not. This prospective observational study was conducted during the endemic period of dengue fever in 2019. A total of 30 diagnosed cases of dengue fever who presented with bicytopenia during febrile phase of the disease were enrolled in this study. Pearson’s correlation coefficient was calculated to compare ferritin levels with lowest platelet count and highest hematocrit level and it showed that there was significant correlation. There was no difference between lowest total count of white blood cell and serum ferritin level. The severity of dengue fever can be predicted by raised level of serum ferritin.

scholarly journals Platelet increment is not associated with endothelial damage in haematological patients: a prospective observational study

2019 ◽  
Vol 79 (6) ◽  
pp. 395-403
Author(s):  
S. Benediktsson ◽  
T. Kander ◽  
S. R. Ostrowski ◽  
P. I. Johansson ◽  
O. D. Thomas ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Endothelial Damage ◽  
Haematological Patients

Prospective Observational Study of Sleep and PTSD Symptoms in Patients Undergoing PTSD Treatment

2009 ◽  
Author(s):  
Ihori Kobayashi ◽  
Brian Hall ◽  
Courtney Hout ◽  
Vanessa Springston ◽  
Patrick Palmieri
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Ptsd Symptoms ◽  
Ptsd Treatment

The 1000Plus study protocol – a prospective observational study on the mismatch concept in a 3.0 T MRI

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
B Hotter ◽  
S Pittl ◽  
M Ebinger ◽  
G Oepen ◽  
K Jegzentis ◽  
...  
Keyword(s):  
Observational Study ◽  
Study Protocol ◽  
Prospective Observational Study ◽  
3.0 T ◽  
3.0 T Mri
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