Classification of patients with non-alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers

2016 ◽  
Vol 47 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Masayuki Mizuno ◽  
Toshihide Shima ◽  
Hirohisa Oya ◽  
Yasuhide Mitsumoto ◽  
Chiemi Mizuno ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Type Iv Collagen ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Type Iv ◽  
Alcoholic Fatty Liver Disease ◽  
Serum Type

scholarly journals Combination of type IV collagen 7S, albumin concentrations, and platelet count predicts prognosis of non-alcoholic fatty liver disease

2021 ◽  
Vol 13 (5) ◽  
pp. 571-583
Author(s):  
Miwa Kawanaka ◽  
Ken Nishino ◽  
Katsunori Ishii ◽  
Tomohiro Tanikawa ◽  
Noriyo Urata ◽  
...  
Keyword(s):  
Platelet Count ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Type Iv Collagen ◽  
Alcoholic Fatty Liver ◽  
Type Iv ◽  
Type Iv Collagen 7S ◽  
Alcoholic Fatty Liver Disease

Performance of autotaxin as a serum marker for liver fibrosis

2017 ◽  
Vol 55 (4) ◽  
pp. 469-477 ◽  
Author(s):  
Hitoshi Ikeda ◽  
Mariko Kobayashi ◽  
Hiromitsu Kumada ◽  
Kenichiro Enooku ◽  
Kazuhiko Koike ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Liver Disease ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Type Iv Collagen ◽  
Alcoholic Fatty Liver ◽  
Type Iv ◽  
Alcoholic Fatty Liver Disease

Background Because autotaxin reportedly has a better performance than hyaluronic acid as a marker for liver fibrosis for the prediction of cirrhosis caused by hepatitis C, we aimed to further evaluate the role of autotaxin in liver fibrosis of other aetiologies. Methods Autotaxin antigen was measured in serum samples from 108 patients with chronic hepatitis B and 128 patients with non-alcoholic fatty liver disease who had undergone a liver biopsy as well as healthy subjects and patients with chronic kidney disease, diabetes mellitus, rheumatoid arthritis and cardiac dysfunction. Results When evaluated using receiver operator characteristics curves, the performance of autotaxin for the prediction of significant fibrosis (F2–F4) in chronic hepatitis B patients was better than that of hyaluronic acid or type IV collagen 7S. In non-alcoholic fatty liver disease patients, however, the performance of autotaxin for the prediction of significant fibrosis was poorer than that of hyaluronic acid or type IV collagen 7S. The increase in the serum autotaxin concentrations was less notable than that of hyaluronic acid or type IV collagen in patients with chronic kidney disease, diabetes mellitus, rheumatoid arthritis or cardiac dysfunction. Food intake did not affect the serum autotaxin concentrations. Conclusions Autotaxin is useful as a serum marker for liver fibrosis caused by not only chronic viral hepatitis C but also by hepatitis B, although it was less useful in patients with non-alcoholic fatty liver disease. The increase in serum autotaxin concentrations is fairly specific for liver fibrosis, and the serum autotaxin concentrations can be analysed without consideration of food intake before blood collection.

scholarly journals Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease

2005 ◽  
Vol 38 (5) ◽  
pp. 747-753 ◽  
Author(s):  
V.N. dos Santos ◽  
M.M.B. Leite-Mór ◽  
M. Kondo ◽  
J.R. Martins ◽  
H. Nader ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Type Iv Collagen ◽  
Alcoholic Fatty Liver ◽  
Type Iv ◽  
Alcoholic Fatty Liver Disease

scholarly journals Roux-en-Y Gastric Bypass Improves Liver Histology in Patients with Non-Alcoholic Fatty Liver Disease

2005 ◽  
Vol 13 (7) ◽  
pp. 1180-1186 ◽  
Author(s):  
Jeanne M. Clark ◽  
Amir R. A. Alkhuraishi ◽  
Steven F. Solga ◽  
Patricia Alli ◽  
Anna Mae Diehl ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

We-P12:293 Associations between carotid artery wall thickness and liver histology in patients with non-alcoholic fatty liver disease

2006 ◽  
Vol 7 (3) ◽  
pp. 411
Author(s):  
G. Targher ◽  
L. Bertolini ◽  
R. Padovani ◽  
S. Rodella ◽  
L. Zenari ◽  
...  
Keyword(s):  
Liver Disease ◽  
Carotid Artery ◽  
Fatty Liver ◽  
Wall Thickness ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Artery Wall ◽  
Alcoholic Fatty Liver ◽  
Carotid Artery Wall ◽  
Alcoholic Fatty Liver Disease

P1067 : Associations between antidiabetic and statin therapy and liver histology in patients with type 2 diabetes and non-alcoholic fatty liver disease

2015 ◽  
Vol 62 ◽  
pp. S749
Author(s):  
F. Nascimbeni ◽  
J. Aron-Wisniewsky ◽  
R. Pais ◽  
J. Tordjman ◽  
F. Charlotte ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Disease ◽  
Fatty Liver ◽  
Statin Therapy ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Role of neuropeptide Y gene variant (rs161477) in liver histology in obese patients with non-alcoholic fatty liver disease

2019 ◽  
Vol 66 (4) ◽  
pp. 217-222 ◽  
Author(s):  
Rocio Aller ◽  
Juan Jose López-Gomez ◽  
Olatz Izaola ◽  
David Primo ◽  
Daniel de Luis
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Neuropeptide Y ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Obese Patients ◽  
Gene Variant ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Role of neuropeptide Y gene variant (rs161477) in liver histology in obese patients with non-alcoholic fatty liver disease

2019 ◽  
Vol 66 (4) ◽  
pp. 217-222
Author(s):  
Rocio Aller ◽  
Juan Jose López-Gomez ◽  
Olatz Izaola ◽  
David Primo ◽  
Daniel de Luis
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Neuropeptide Y ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Obese Patients ◽  
Gene Variant ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease
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