scholarly journals Dexamethasone in COVID‐19: Should we consider a "golden hour" practice?

2021 ◽  
Vol 75 (11) ◽  
Author(s):  
Karolina Akinosoglou ◽  
Charalambos Gogos
Keyword(s):  
2009 ◽  
Vol 2 (3) ◽  
pp. 8
Author(s):  
ROBERT FINN
Keyword(s):  

2019 ◽  
Author(s):  
Angela Taylor ◽  
Conor Bentley ◽  
Mark Foster ◽  
Janet Lord ◽  
Jon Hazeldine ◽  
...  

2020 ◽  
Vol 11 (3) ◽  
pp. 292-309
Author(s):  
Yosreah Mohamed Mohamed ◽  
Arzak Mohamed Khalifa ◽  
Fatma Abdou Eltaib

Children ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 301
Author(s):  
Andrew M. Dylag ◽  
Jamey Tulloch ◽  
Karen E. Paul ◽  
Jeffrey M. Meyers

Background: Prevention of chronic lung disease (CLD) requires a multidisciplinary approach spanning from the delivery room to Neonatal Intensive Care Unit (NICU) discharge. In 2018, a quality improvement (QI) initiative commenced in a level 4 NICU with the goal of decreasing chronic lung disease rates below the Vermont Oxford Network (VON) average of 24%. Methods: Improvement strategies focused on addressing the primary drivers of ventilation strategies, surfactant administration, non-invasive ventilation, medication use, and nutrition/fluid management. The primary outcome was VON CLD, defined as need for mechanical ventilation and/or supplemental oxygen use at 36 weeks postmenstrual age. Statistical process control charts were used to display and analyze data over time. Results: The overall CLD rate decreased from 33.5 to 16.5% following several interventions, a 51% reduction that has been sustained for >18 months. Changes most attributable to this include implementation of the “golden hour” gestational age (GA) based delivery room protocol that encourages early surfactant administration and timely extubation. Fewer infants were intubated across all GA groups with the largest improvement among infants 26–27 weeks GA. Conclusions: Our efforts significantly decreased CLD through GA-based respiratory guidelines and a comprehensive, rigorous QI approach that can be applicable to other teams focused on improvement.


Author(s):  
Subbiah Venkatesh Babu

AbstractGlobally the road accidents had become a great burden and claiming lot of precious lives today. However, the initial treatment within the first hour of the injury indeed had proven the high chance of survival after the trauma. This article updates and signifies the systematic emergency approach and current principles in saving lives after injury.


Author(s):  
Rodica Di Lorenzo ◽  
Maher Saqqur ◽  
Andrew Blake Buletko ◽  
Lacy Sam Handshoe ◽  
Bhageeradh Mulpur ◽  
...  

Author(s):  
Rodolfo C. Pacagnella ◽  
Anderson Borovac‐Pinheiro ◽  
Carla Silveira ◽  
Sirlei Siani Morais ◽  
Juliana Luz Passos Argenton ◽  
...  

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Martin Ebinger ◽  
Matthias Wendt ◽  
Michal Rozanski ◽  
Benjamin Winter ◽  
Carolin Waldschmidt ◽  
...  

Objective: The effectiveness of intravenous thrombolysis in acute ischemic stroke is time dependent. The effects are likely to be highest if onset-to-treatment time (OTT) is < 60 minutes, the so called Golden-Hour. Starting thrombolysis in a specialized ambulance with a CT-scanner plus point-of-care laboratory reduced time from emergency call to treatment in the prospective controlled PHANTOM-S study. We evaluated the rate and effectiveness of Golden-Hour thrombolysis. Methods: The stroke emergency mobile (STEMO) is staffed with a neurologist trained in emergency medicine, a paramedic and a technician. The effects of the STEMO implementation were evaluated in a prospective study comparing weeks with and without STEMO-availability. STEMO was deployed when the dispatchers suspected an acute stroke during emergency calls. If STEMO was not available (in operation or maintenance), patients received conventional care. OTT-intervals were dichotomized in either ≤60 (Golden-Hour) or > 60 minutes as well as categorized in 10-minute intervals from 0 to 270 minutes for graphical description. Results: Overall, thrombolysis rates in ischemic stroke were 33% (200/614) when STEMO was deployed and 22% (330/1497) in conventional care (p<0.001). The proportion of Golden-Hour treatments (from all thrombolysis) was 6-fold higher after STEMO deployment (31.0%; n= 62 versus 4.9%; n=16; p<0.01). Compared to patients with longer OTT patients with Golden-Hour thrombolysis had no higher risks for 7- or 90-day mortality (adjusted ORs: 0.38, 95%-CI: 0.09-1.70 and 0.69, 95%-CI: 0.32-1.53) but were more likely to be discharged at home (adjusted OR: 1.93 95%CI: 1.09-3.41; p=0.024). Conclusion: STEMO increased the percentage of patients treated within the Golden-Hour. This entailed no risk to patients’ safety and was associated with better short-term outcome.


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