CCL2, CCL3 and CCL4 gene polymorphisms in pulmonary tuberculosis patients of South India

2013 ◽  
Vol 41 (2) ◽  
pp. 98-104 ◽  
Author(s):  
B. Singh ◽  
J. Chitra ◽  
P. Selvaraj
Keyword(s):  
Pulmonary Tuberculosis ◽  
Gene Polymorphisms ◽  
South India ◽  
Tuberculosis Patients

Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India

Tuberculosis ◽  
2010 ◽  
Vol 90 (5) ◽  
pp. 306-310 ◽  
Author(s):  
P. Selvaraj ◽  
M. Harishankar ◽  
Brijendra Singh ◽  
M.S. Jawahar ◽  
V.V. Banurekha
Keyword(s):  
Pulmonary Tuberculosis ◽  
Gene Polymorphisms ◽  
South India ◽  
Toll Like Receptor ◽  
Tuberculosis Patients

scholarly journals Cytokine Polymorphisms, Their Influence and Levels in Brazilian Patients with Pulmonary Tuberculosis during Antituberculosis Treatment

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Eliana Peresi ◽  
Larissa Ragozo Cardoso Oliveira ◽  
Weber Laurentino da Silva ◽  
Érika Alessandra Pellison Nunes da Costa ◽  
João Pessoa Araujo ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Plasma Levels ◽  
Gene Polymorphisms ◽  
Essential Role ◽  
Active Tuberculosis ◽  
Mrna Levels ◽  
Tuberculosis Patients ◽  
Antituberculosis Treatment ◽  
Cytokine Levels ◽  
Tuberculosis Disease

Cytokines play an essential role during active tuberculosis disease and cytokine genes have been described in association with altered cytokine levels. Therefore, the aim of this study was to verify ifIFNG, IL12B, TNF, IL17A, IL10, and TGFB1gene polymorphisms influence the immune response of Brazilian patients with pulmonary tuberculosis (PTB) at different time points of antituberculosis treatment (T1, T2, and T3). Our results showed the following associations:IFNG+874 T allele andIFNG+2109 A allele with higher IFN-γlevels;IL12B+1188 C allele with higher IL-12 levels;TNF−308 A allele with higher TNF-αplasma levels in controls and mRNA levels in PTB patients at T1;IL17AA allele at rs7747909 with higher IL-17 levels;IL10−819 T allele with higher IL-10 levels; andTGFB1+29 CC genotype higher TGF-βplasma levels in PTB patients at T2. The present study suggests thatIFNG+874T/A,IFNG+2109A/G,IL12B+1188A/C,IL10−819C/T, andTGFB1+21C/T are associated with differential cytokine levels in pulmonary tuberculosis patients and may play a role in the initiation and maintenance of acquired cellular immunity to tuberculosis and in the outcome of the active disease while on antituberculosis treatment.

Sputum collection and disposal among pulmonary tuberculosis patients in coastal South India [Short communication]

2013 ◽  
Vol 17 (5) ◽  
pp. 621-623
Author(s):  
T. Rekha ◽  
P. Singh ◽  
B. Unnikrishnan ◽  
P. Prasanna Mithra ◽  
N. Kumar ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
South India ◽  
Short Communication ◽  
Tuberculosis Patients
Sign in / Sign up

Export Citation Format

Share Document