Salivary flow rate and oral findings in Prader-Willi syndrome: a case-control study

ABSTRACT Aims and objectives The study determined the relationship between chronic kidney disease (CKD) and changes in salivary flow and the complications of reduced salivary flow among African subjects with CKD compared with the controls. Materials and methods One hundred and eighty patients, 90 CKD and 90 controls were recruited, interviewed and examined. Stimulated and unstimulated saliva collection was done with standardized spitting method. Urinalysis and blood creatinine levels were determined and glomerular filtration rate (GFR) of each patient was calculated from the blood creatinine using Cockcroft and Gault formula. Statistical analysis was done using STATA 11 software. Results The mean stimulated and unstimulated whole salivary flow rate among CKD subjects were 4.07 ± 1.91 and 2.34 ± 0.99 ml/5 min respectively and is significantly lower than that of the controls which were 8.05 ± 3.95 ml/5 min and 3.82 ± 2.27 ml/5 min for stimulated and unstimulated flow rates. Oral signs of reduced salivary flow were found in 80% of CKD patients. The commonest oral finding was taste abnormalities others are burning sensation, halitosis and difficulty in mastication. Conclusion Patients with CKD had reduced stimulated and unstimulated salivary flow rate. Reduced salivary flow was associated with oral lesions in majority (80%) of CKD patients, the commonest finding being taste abnormalities. How to cite this article Oyetola EO, Owotade FJ, Agbelusi GA, Fatusi O, Sanusi A, Adesina OM. Salivary Flow Rates of Nigerian Patients with Chronic Kidney Disease: A Case-control Study. J Contemp Dent Pract 2015;16(4):264-269.

Download Full-text

Comparative evaluation of alteration in salivary flow rate between betal Nut/Gutkha chewers with and without OSMF, and healthy subjects: A prospective case-control study

Oncology Journal of India ◽

10.4103/oji.oji_22_20 ◽

2021 ◽

Vol 5 (1) ◽

pp. 1

Author(s):

AbhishekSingh Nayyar ◽

F Lalfamkima ◽

SureshBabu Bommaji ◽

KailasaKumar Reddy ◽

KVenkata Chalapathi ◽

...

Keyword(s):

Flow Rate ◽

Healthy Subjects ◽

Comparative Evaluation ◽

Case Control Study ◽

Salivary Flow ◽

Case Control ◽

Salivary Flow Rate ◽

Control Study ◽

Prospective Case Control Study

Download Full-text

Relationship of psychological factors with salivary flow rate and cortisol levels in individuals with oral lichen planus: A case-control study

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2020.10.004 ◽

2020 ◽

Vol 130 (6) ◽

pp. 675-680

Author(s):

Alessandra Laís Pinho Valente Pires ◽

Juliana Araújo da Silva Simoura ◽

Joana Dourado Martins Cerqueira ◽

Ynara Bosco de Oliveira Lima-Arsati ◽

Franco Arsati ◽

...

Keyword(s):

Lichen Planus ◽

Flow Rate ◽

Psychological Factors ◽

Oral Lichen Planus ◽

Case Control Study ◽

Salivary Flow ◽

Case Control ◽

Relationship Of ◽

Oral Lichen ◽

Control Study

Download Full-text

Oral disorders in Children with Prader–Willi syndrome: a case control study

Orphanet Journal of Rare Diseases ◽

10.1186/s13023-020-01566-7 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Sonal Lavakumar Budihal ◽

Aya Mohammad Ahmad ◽

Adama Sani Usman ◽

Anusha Sreejith ◽

Jayadevan Sreedharan

Keyword(s):

Case Control Study ◽

Case Control ◽

Prader Willi Syndrome ◽

Control Study

Download Full-text

Salivary and microbiological parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus: a case-control study

Revista de Odontologia da UNESP ◽

10.1590/rou.2014.030 ◽

2014 ◽

Vol 43 (3) ◽

pp. 196-202

Author(s):

José Roberto CORTELLI ◽

Regina Márcia Serpa PINHEIRO ◽

Fernando de Oliveira COSTA ◽

Davi Romeiro AQUINO ◽

Suzane A RASLAN ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Flow Rate ◽

Chronic Periodontitis ◽

Case Control Study ◽

Case Control ◽

Glucose Levels ◽

Control Study

Background: Several studies have investigated the differences in salivary parameters and microbial composition between diabetic and non-diabetic patients, however, specific differences are still not clear mainly due to the effects of confounder. Aim: The aim of this case-control study was to evaluate the salivary and microbial parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus. Material and method: This case-control study included 60 chronic periodontitis subjects, 30 diabetics (case group) and 30 non-diabetics (control group), paired according to periodontitis severity, gender and age. Stimulated whole saliva was collected from all volunteers to measure the salivary pH and the salivary flow rate. Bacterial samples were collected with paper points from periodontal sites showing the deepest periodontal pocket depth associated with the highest clinical attachment loss. The frequency of A. actinomycetemcomitans, P. intermedia, P. gingivalis, T. forsythia and C. rectus was evaluated by PCR. Data was statistically analyzed by Student's t, Mann-Whitney and Chi-square (p<0.05). Result: Diabetic subjects showed higher salivary glucose levels and lower stimulated flow rates in comparison to non-diabetic controls. P. gingivalis and T. forsythia were the most frequent pathogens (p<0.05). Bacterial frequency did not differ between case and control groups. Conclusion: Diabetes status influenced salivary glucose levels and flow rate. Within the same severity of chronic periodontitis, diabetic subjects did not show higher frequency of periodontal pathogens in comparison to their paired controls.

Download Full-text