Experimental hut trials of permethrin-impregnated mosquito nets and eave curtains against malaria vectors in Tanzania

1987 ◽  
Vol 1 (1) ◽  
pp. 37-51 ◽  
Author(s):  
J. D. LINES ◽  
J. MYAMBA ◽  
C. F. CURTIS
Keyword(s):  
Malaria Vectors ◽  
Experimental Hut ◽  
Mosquito Nets

scholarly journals Human biting rhythm of Anopheles gambiae Giles, 1902 (Diptera: Culicidae) and sleeping behaviour of pregnant women in a lagoon area in Southern Benin

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Armel Djènontin ◽  
Aziz Bouraima ◽  
Christophe Soares ◽  
Seun Egbinola ◽  
Gilles Cottrell
Keyword(s):  
Plasmodium Falciparum ◽  
Pregnant Women ◽  
Anopheles Gambiae ◽  
Early Morning ◽  
Allelic Frequency ◽  
Malaria Vectors ◽  
Mosquito Nets ◽  
Anopheles Gambiae Giles ◽  
Almost All ◽  
Southern Benin

Abstract Objective In the framework of EVALMOUS study aiming to assess the use and effectiveness of mosquito nets by pregnant women and other members of their household in a lagoon area in southern Benin, the behaviour of pregnant women relative to the time they go to bed using the net were recorded. Malaria vectors biting rhythm, Plasmodium falciparum infection and insecticide resistance genes in malaria vectors were also determined. Results Overall, 3848 females of Anopheles gambiae s. l were collected and 280 pregnant women responded to the survey. Almost all Anopheles gambiae s. l. tested were Anopheles coluzzi Coetzee and Wilkerson 2013 (Diptera: Culicidae). The CSP index in malaria vector was 1.85% and the allelic frequency of kdr gene was 74.4%. Around 90% of bites and Plasmodium falciparum Welch, 1897 (Haemosporida: Plasmodiidae) transmission occurred between 10 p.m. and 6 a.m., which coincides with the period when more than 80% of pregnant women were under bednet. Despite a slight early evening and early morning biting activity of malaria vectors in the study area, the good use of nets might remain a useful protection tool against mosquito biting and malaria transmission.

Behavioural and insecticidal effects of organophosphate-, carbamate- and pyrethroid-treated mosquito nets against African malaria vectors

2009 ◽  
Vol 23 (4) ◽  
pp. 317-325 ◽  
Author(s):  
R. C. MALIMA ◽  
R. M. OXBOROUGH ◽  
P. K. TUNGU ◽  
C. MAXWELL ◽  
I. LYIMO ◽  
...  
Keyword(s):  
Malaria Vectors ◽  
Mosquito Nets

scholarly journals Bionomics and insecticides resistance profiling of malaria vectors at a selected site for experimental hut trials in central Cameroon

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Benjamin D. Menze ◽  
Murielle J. Wondji ◽  
William Tchapga ◽  
Micareme Tchoupo ◽  
Jacob M. Riveron ◽  
...  
Keyword(s):  
Malaria Vectors ◽  
Experimental Hut

scholarly journals An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector Anopheles funestus Reveals a Loss of Bed Nets Efficacy Associated with GSTe2 Metabolic Resistance

Genes ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 143 ◽  
Author(s):  
Benjamin D. Menze ◽  
Mersimine F. Kouamo ◽  
Murielle J. Wondji ◽  
Williams Tchapga ◽  
Micareme Tchoupo ◽  
...  
Keyword(s):  
Anopheles Funestus ◽  
Blood Feeding ◽  
Malaria Vectors ◽  
Bed Nets ◽  
Glutathione S Transferase ◽  
Metabolic Resistance ◽  
Experimental Hut ◽  
The Impact ◽  
Long Lasting Insecticidal Nets ◽  
Permanet 3.0

Growing insecticide resistance in malaria vectors is threatening the effectiveness of insecticide-based interventions, including Long Lasting Insecticidal Nets (LLINs). However, the impact of metabolic resistance on the effectiveness of these tools remains poorly characterized. Using experimental hut trials and genotyping of a glutathione S-transferase resistance marker (L119F-GSTe2), we established that GST-mediated resistance is reducing the efficacy of LLINs against Anopheles funestus. Hut trials performed in Cameroon revealed that Piperonyl butoxide (PBO)-based nets induced a significantly higher mortality against pyrethroid resistant An. funestus than pyrethroid-only nets. Blood feeding rate and deterrence were significantly higher in all LLINs than control. Genotyping the L119F-GSTe2 mutation revealed that, for permethrin-based nets, 119F-GSTe2 resistant mosquitoes have a greater ability to blood feed than susceptible while the opposite effect is observed for deltamethrin-based nets. For Olyset Plus, a significant association with exophily was observed in resistant mosquitoes (OR = 11.7; p < 0.01). Furthermore, GSTe2-resistant mosquitoes (cone assays) significantly survived with PermaNet 2.0 (OR = 2.1; p < 0.01) and PermaNet 3.0 (side) (OR = 30.1; p < 0.001) but not for Olyset Plus. This study shows that the efficacy of PBO-based nets (e.g., blood feeding inhibition) against pyrethroid resistant malaria vectors could be impacted by other mechanisms including GST-mediated metabolic resistance not affected by the synergistic action of PBO. Mosaic LLINs incorporating a GST inhibitor (diethyl maleate) could help improve their efficacy in areas of GST-mediated resistance.

Village-scale evaluation of mosquito nets treated with a tablet formulation of deltamethrin against malaria vectors

2005 ◽  
Vol 19 (3) ◽  
pp. 286-292 ◽  
Author(s):  
S. K. Sharma ◽  
A. K. Upadhyay ◽  
M. A. Haque ◽  
K. Padhan ◽  
P. K. Tyagi ◽  
...  
Keyword(s):  
Tablet Formulation ◽  
Malaria Vectors ◽  
Scale Evaluation ◽  
Mosquito Nets

scholarly journals Indoor Use of Plastic Sheeting Impregnated with Carbamate Combined with Long-Lasting Insecticidal Mosquito Nets for the Control of Pyrethroid-Resistant Malaria Vectors

2010 ◽  
Vol 83 (2) ◽  
pp. 266-270 ◽  
Author(s):  
Armel Djènontin ◽  
Martin Akogbéto ◽  
Fabrice Chandre ◽  
Vincent Corbel ◽  
Raphael N'Guessan ◽  
...  
Keyword(s):  
Malaria Vectors ◽  
Mosquito Nets

scholarly journals Passive Outdoor Host Seeking Device (POHD): Designing and Evaluation against Outdoor Biting Malaria Vectors

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Stella T. Kessy ◽  
Ladslaus L. Mnyone ◽  
Bruno A. Nyundo ◽  
Issa N. Lyimo
Keyword(s):  
Carbon Dioxide ◽  
Malaria Transmission ◽  
Indoor Residual Spraying ◽  
Malaria Vectors ◽  
Natural Environments ◽  
Release Formulation ◽  
Experimental Hut ◽  
Host Seeking ◽  
Outdoor Biting ◽  
Residual Malaria Transmission

Odor-baited devices are increasingly needed to compliment long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) for control of residual malaria transmission. However, the odor-baited devices developed so far are bulky, dependent on the source of electricity and carbon dioxide (CO2), and they are logistically unsuitable for scaling up in surveillance and control of malaria vectors. We designed a passive and portable outdoor host seeking device (POHD) and preliminarily evaluated suitable components against Anopheles arabiensis that maintains residual malaria transmission. Experiments were conducted using semifield reared An. arabiensis within the semifield system at Ifakara Health Institute (IHI) in southeastern Tanzania. These mosquitoes were exposed to Suna traps® baited with BG lures or source of light and augmented with carbon dioxide (CO2) in view of identifying best attractants necessary to improve attractiveness of designed POHD. Two Suna traps® were hanged at the corner but outside the experimental hut in a diagonal line and rotated between four corners to control for the effect of position and wind direction on mosquito catches. Furthermore, mosquitoes were also exposed to either a bendiocarb-treated or bendiocarb-untreated POHD baited with Mbita blend, Ifakara blend, and worn socks and augmented with warmth (i.e., 1.5 liter bottle of warm water) inside an experimental hut or a screened rectangular box. This study demonstrated that mosquitoes were more strongly attracted to Suna trap® baited with BG lures and CO2 relative to those traps baited with a source of light and CO2. The POHD baited with synthetic blends attracted and killed greater proportion of An. arabiensis compared with POHD baited with worn socks. Efficacy of the POHD was unaffected by source of warmth, and it was reduced by about 50% when the device was tested inside a screened rectangular box relative to closed experimental hut. Overall, this study demonstrates that the POHD baited with synthetic blends (Mbita and Ifakara blends) and bendiocarb can effectively attract and kill outdoor biting malaria vector species. Such POHD baited with synthetic blends may require the source of CO2 to enhance attractiveness to mosquitoes. Further trials are, therefore, ongoing to evaluate attractiveness of improved design of POHD baited with slow-release formulation of synthetic blends and sustainable source of CO2 to malaria vectors under semifield and natural environments.

scholarly journals Deteksi Gen Kdr pada Nyamuk Anopheles di Kabupaten Maluku Tenggara Barat

2021 ◽  
pp. 161-170
Author(s):  
Hanna S.I Kawulur ◽  
Hotma Martogi Lorensi Hutapea ◽  
Ivon Ayomi ◽  
Melda Suebu ◽  
Mardi Raharjo Pardi
Keyword(s):  
Malaria Vectors ◽  
Bed Nets ◽  
Morbidity Rate ◽  
Gene Detection ◽  
Paper Test ◽  
Anopheles Subpictus ◽  
Pyrethroid Insecticides ◽  
Mosquito Nets ◽  
Development Center ◽  
Anopheles Barbirostris

Malaria is still a health problem in Indonesia, particularly in Eastern part of Indonesia. The use of LLIN insecticide bed nets is one of the efforts to reduce the malaria morbidity rate by protecting human from malaria vector bites. The Anopheles flavirostris, Anopheles barbirostris, and Anopheles subpictus mosquitoes are three of the species reported as malaria vectors in West-Southeast Maluku Regency. The aim of this research was to detect the kdr gene in An. flavirostris, An. barbirostris, and An.subpictus mosquitoes collected from Alusi Kelaan village, West-Southeast Maluku Regency. The research was conducted at the Papua Biomedical Research and Development Center, in June 2016. A total of six An. flavirostris, 42 An. barbirostris, and 24 An. subpictus were pooled separately for genomic DNA extraction. The sample used was the An. flavirostris, An. barbirostris, and An. subpictus that survived after the impregnated paper test. The kdr gene detection was carried out using quantitative PCR (qPCR) focused on points V1010 and L1014. The results showed that there were no kdr mutant strains in the An. flavirostris, An. barbirostris, and An. subpictus. These results indicated that the sensitivity of pyrethroid insecticides contained in LLIN mosquito nets to An. flavirostris, An. barbirostris, and An. subpictus mosquitoes was not decreased in West Southeast Maluku Regency.

scholarly journals Evaluation of ICON Maxx, a long-lasting treatment kit for mosquito nets: experimental hut trials against anopheline mosquitoes in Tanzania

2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Patrick K. Tungu ◽  
Robert Malima ◽  
Frank W. Mosha ◽  
Issa Lyimo ◽  
Caroline Maxwell ◽  
...  
Keyword(s):  
Experimental Hut ◽  
Mosquito Nets ◽  
Anopheline Mosquitoes

scholarly journals Anopheles gambiae populations from Burkina Faso show minimal delayed mortality after exposure to insecticide-treated nets

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Angela Hughes ◽  
Natalie Lissenden ◽  
Mafalda Viana ◽  
Kobié Hyacinthe Toé ◽  
Hilary Ranson
Keyword(s):  
Burkina Faso ◽  
Anopheles Gambiae ◽  
Pyrethroid Resistance ◽  
Malaria Vectors ◽  
Insecticide Treated Nets ◽  
Experimental Hut ◽  
Transmission Potential ◽  
Mortality Effect ◽  
Delayed Mortality ◽  
The Impact

Abstract Background The efficacy of long-lasting insecticidal nets (LLINs) in preventing malaria in Africa is threatened by insecticide resistance. Bioassays assessing 24-hour mortality post-LLIN exposure have established that resistance to the concentration of pyrethroids used in LLINs is widespread. However, although mosquitoes may no longer be rapidly killed by LLIN exposure, a delayed mortality effect has been shown to reduce the transmission potential of mosquitoes exposed to nets. This has been postulated to partially explain the continued efficacy of LLINs against pyrethroid-resistant populations. Burkina Faso is one of a number of countries with very high malaria burdens and pyrethroid-resistant vectors, where progress in controlling this disease has stagnated. We measured the impact of LLIN exposure on mosquito longevity in an area of the country with intense pyrethroid resistance to establish whether pyrethroid exposure was still shortening mosquito lifespan in this setting. Methods We quantified the immediate and delayed mortality effects of LLIN exposure using standard laboratory WHO cone tests, tube bioassays and experimental hut trials on Anopheles gambiae populations originating from the Cascades region of Burkina Faso using survival analysis and a Bayesian state-space model. Results Following single and multiple exposures to a PermaNet 2.0 LLIN only one of the four mosquito populations tested showed evidence of delayed mortality. No delayed mortality was seen in experimental hut studies using LLINs. A delayed mortality effect was only observed in WHO tube bioassays when deltamethrin concentration was increased above the standard diagnostic dose. Conclusions As mosquito pyrethroid-resistance increases in intensity, delayed effects from LLIN exposure are substantially reduced or absent. Given the rapid increase in resistance occurring in malaria vectors across Africa it is important to determine whether the failure of LLINs to shorten mosquito lifespan is now a widespread phenomenon as this will have important implications for the future of this pivotal malaria control tool.

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