Atelectasis of the right medial basal segment mimicking primary lung cancer in an asthmatic patient

2005 ◽  
Vol 59 ◽  
pp. 109-110 ◽  
Author(s):  
A. Naito ◽  
H. Satoh ◽  
M. Ohtsuka ◽  
K. Sekizawa
2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Changjiang Liu ◽  
Chengang Liu ◽  
Xiao Zou ◽  
Lin Shao ◽  
Ying Sun ◽  
...  

Abstract Background In lung cancer management, differential diagnosis between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IMP) is a critical point that is of direct therapeutic and clinical importance. However, this process often suffers from absence of a gold standard, resulting in equivocal cases. Herein, we present a series of three cases, in which genomic alteration patterns revealed by next-generation sequencing (NGS) facilitated the differential diagnosis between MPLC and IMP. Case presentation Case 1 was a 57-year-old female with two separate lesions in the upper lobe and the lower lobe of left lung, which were both histopathologically determined as T2aN0M0 adenocarcinomas. NGS identified an EGFR L858R in one lesion and an EGFR 20 exon insertion in the other one, suggestive of double primary malignancies. The patient underwent wedge resections and received an adjuvant treatment of icotinib and chemotherapy. She had a disease-free survival (DFS) of 19 months and counting. Case 2 was a 55-year-old female with multiple small lesions in both lungs. Histopathological examinations of resected lesions from right upper lobe revealed three subtypes: atypical adenomatous hyperplasia of alveolar epithelium, adenocarcinomas in situ and minimally invasive adenocarcinoma. NGS identified two different BRAF driver mutations G466E and V600_K601delinsE in two lesions of adenocarcinoma in situ, and a BRAF K601E in a lesion of minimally invasive adenocarcinoma. Case 3, a 68-year-old male, had the right upper lobe lesion histophathologically classified as a stage T3NxM0 mixed adenoneuroendocrine carcinoma and the left upper lobe lesion as a stage T1aN0M0 adenocarcinoma. NGS performed with different loci of surgical tissues revealed a rare sensitizing EGFR mutation G719A shared by the right upper lobe lesion and lymph node, and two EGFR mutations L861Q and G719S in left upper lobe lesion. The patient received icotinib treatment postoperatively and achieved a stable disease with a progression-free survival of 5 months. Conclusion Our cases provide evidence for utility of NGS in facilitating diagnosis and treatment decisions.


1991 ◽  
Vol 5 (5) ◽  
pp. 514-519
Author(s):  
Makoto Nonaka ◽  
Takashi Arai ◽  
Keizou Inagaki ◽  
Takatorno Morita ◽  
Makoto Yana ◽  
...  

2015 ◽  
Vol 9 (7-8) ◽  
pp. 524
Author(s):  
Yusuke Muro ◽  
Takeo Kosaka ◽  
Tai Hato ◽  
Shuji Mikami ◽  
Mototsugu Oya

We report an extremely rare case of 79-year-old man, who was discovered with coincidental lung metastasis of prostate cancer and primary lung cancer. The patient presented with low prostatespecific antigen and two lung lesions: one in the right lower lobe, and one in the right upper lobe, 3 years after, he was treated with external beam radiotherapy for Gleason score 4+3=7, cT3aN0M0 prostate cancer. A computed tomography-guided needle biopsy of a nodule in the right lower lobe revealed suspicious metastasis of prostate cancer. Thoracoscopic excisions of both lesions were performed, and each lung lesion was diagnosed as being metastatic prostate cancer and primary lung cancer.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Koichi Fukumoto ◽  
Madoka Goto ◽  
Yasuhisa Ichikawa ◽  
Yuta Kawasumi ◽  
Mika Uchiyama ◽  
...  

Abstract Background There have been few reports on surgically treated primary lung cancer accompanied by contralateral partial anomalous pulmonary venous connection (PAPVC). In such cases, repair of the PAPVC might be necessary to avoid postoperative right-heart failure due to the increased flow of the left-to-right shunt. Case presentation We herein report a case of lung adenocarcinoma treated by left-upper lobectomy with bronchoplasty and pulmonary arterial angioplasty after induction chemoradiation therapy followed by surgical correction of the PAPVC in the right-upper lobe. The patient is alive without recurrence of lung cancer or any symptoms of heart failure 17 months after pulmonary resection. Conclusion When considering performing major pulmonary resection for lung tumor, thoracic surgeons should pay close attention to the presence of a PAPVC not only on the ipsilateral side of the lung tumor, but also the contralateral side, although it is a rare phenomenon.


2021 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Yoshihiro Miyashita ◽  
Miyuki Kobayashi ◽  
Yumiko Kakizaki ◽  
Toshiharu Tsutsui ◽  
Takashi Kumagai ◽  
...  

A 67-year-old patient visited the hospital for the evaluation of pulmonary nodular lesions detected in his chest radiograph duringan annual screening. He was asymptomatic and transbronchial tumor biopsy of the nodule in the right upper lobe revealed features of pulmonary sarcoma, which did not resemble any of the histolopathological categories of primary lung cancer. A positive immunological staining for both HMB-45 and Melan-A resulted in the final diagnosis of melanoma. It is important for a respiratory clinician to remind the possibility of a melanoma, when tumors cannot be histopathologically classified under any of the categories of primary lung cancer.


2016 ◽  
Vol 352 (4) ◽  
pp. 427
Author(s):  
Matias Migliaro ◽  
David H. Ballard ◽  
Amol Takalkar ◽  
Jaiyeola O. Thomas-Ogunniyi ◽  
Carlos H. Previgliano ◽  
...  

2015 ◽  
Vol 6 (6) ◽  
pp. 672-677 ◽  
Author(s):  
Kenji Tomizawa ◽  
Kenichi Suda ◽  
Toshiki Takemoto ◽  
Tetsuya Mizuno ◽  
Hiroaki Kuroda ◽  
...  

1999 ◽  
Vol 40 (5) ◽  
pp. 879
Author(s):  
Young Min Kim ◽  
Jin Hwan Kim ◽  
Chang Kyu Yang ◽  
Bin Young Jung ◽  
Kwang Jin Jun ◽  
...  

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1861-1868
Author(s):  
Bianca Princeton ◽  
Abilasha R ◽  
Preetha S

Oral hygiene is defined as the practice of keeping the mouth clean and healthy, by brushing and flossing to prevent the occurrence of any gum diseases like periodontitis or gingivitis. The main aim of oral health hygiene is to prevent the buildup of plaque, which is defined as a sticky film of bacteria and food formed on the teeth. The coastal guard is an official who is employed to watch the sea near a coast for ships that are in danger or involved with illegal activities. Coastal guards have high possibilities of being affected by mesothelioma or lung cancer due to asbestos exposure. So, a questionnaire consisting of 20 questions was created and circulated among a hundred participants who were coastal guards, through Google forms. The responses were recorded and tabulated in the form of bar graphs. Out of a hundred participants, 52.4% were not aware of the fact that coastal guards have high chances of developing lung cancer and Mesothelioma. 53.7% were aware of the other oral manifestations of lung cancer other than bleeding gums. Majority of the coastal guards feel that they are given enough information about dental hygiene protocols. Hence, to conclude, oral hygiene habits have to be elaborated using various tools in the right manner to ensure better health of teeth and gums.


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