The potential role of C-reactive protein in distinguishing cytomegalovirus from tuberculosis and bacterial infections in renal transplant recipients

2009 ◽  
Vol 23 (5) ◽  
pp. 710-715 ◽  
Author(s):  
Elerson C. Costalonga ◽  
Natalia C.V. Melo ◽  
Camila E. Rodrigues ◽  
Luis H.B.C. Sette ◽  
Luiz E. Ianhez
Keyword(s):  
Renal Transplant ◽  
Bacterial Infections ◽  
Potential Role ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
C Reactive Protein ◽  
Reactive Protein

Mycophenolate Mofetil and C-Reactive Protein in Renal Transplant Recipients

2007 ◽  
Vol 83 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Brian M. Wong ◽  
Michael Huang ◽  
Jeffrey S. Zaltzman ◽  
G V. Ramesh Prasad
Keyword(s):  
Mycophenolate Mofetil ◽  
Renal Transplant ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals An Increase in Myeloid-Related Protein Serum Levels Precedes Acute Renal Allograft Rejection

2001 ◽  
Vol 12 (9) ◽  
pp. 1947-1957
Author(s):  
KLAUS BURKHARDT ◽  
MARTIN RADESPIEL-TRÖGER ◽  
HARALD D. RUPPRECHT ◽  
MARGARETE GOPPELT-STRUEBE ◽  
REGINE RIESS ◽  
...  
Keyword(s):  
Pilot Study ◽  
Renal Transplant ◽  
Acute Rejection ◽  
High Sensitivity ◽  
Serum Levels ◽  
Renal Transplant Recipients ◽  
Related Protein ◽  
Transplant Recipients ◽  
C Reactive Protein ◽  
Reactive Protein

Abstract. Upon interaction with activated endothelium, monocytes and neutrophils form complexes of myeloid-related protein 8 (MRP8) (S100A8) and MRP14 (S100A9), two members of the calcium-binding S100 family that are secreted during transendothelial migration. In a pilot study of 20 renal transplant recipients and a validation study of 36 renal transplant recipients, MRP8/14 serum levels were measured with an enzyme-linked immunosorbent assay for 28 d, associated with C-reactive protein and creatinine serum levels, and grouped according to biopsy-proven acute rejection. Serum levels of MRP8/14 but not C-reactive protein were significantly increased for several days during the first 2 wk for the acute rejection groups in both studies (P < 0.005, on day 6 after transplantation). As determined by using receiver operating characteristic curves, the optimal cutoff for 100% specificity and high sensitivity (67%) for acute rejection on day 6 after transplantation was calculated to be 4.2 μg/ml for MRP8/14 in the pilot study; this value was confirmed in the validation study. Positive MRP8/14 serum levels preceded acute rejection episodes by a median of 5 d. A 3-d course of intravenous methylprednisolone therapy reduced prerejection MRP8/14 serum levels from 5.7 μg/ml to 3.3 μg/ml (P < 0.05). All MRP8/14 serum levels were below the cutoff during urinary tract infections, delayed graft function, or cytomegalovirus infections, and these values did not differ significantly from control values. It is concluded that the MRP8/14 complex is a very early serum marker suitable for monitoring of acute rejection with high sensitivity and specificity.

scholarly journals Abdominal obesity and smoking are important determinants of C-reactive protein in renal transplant recipients

2005 ◽  
Vol 20 (11) ◽  
pp. 2524-2531 ◽  
Author(s):  
Rutger M. van Ree ◽  
Aiko P. J. de Vries ◽  
Leendert H. Oterdoom ◽  
T. Hauw The ◽  
Ron T. Gansevoort ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Abdominal Obesity ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
C Reactive Protein ◽  
Reactive Protein

P9.7 C-REACTIVE PROTEIN, CYSTATIN C AND ARTERIAL STIFFNESS IN RENAL TRANSPLANT RECIPIENTS

2014 ◽  
Vol 8 (4) ◽  
pp. 155
Author(s):  
M. Harangi ◽  
R. Szentimrei ◽  
L. Lőcsey ◽  
I. Seres ◽  
D. Kovács ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Arterial Stiffness ◽  
Cystatin C ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
C Reactive Protein ◽  
Reactive Protein
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