Carotid intima-media thickness in children and young adults with renal transplant: Internal carotid artery vs. common carotid artery

Abstract Purpose Inhomogeneity of arterial wall thickness may be indicative of distal plaques. This study investigates the intra-subject association between relative spatial intima-media thickness (IMT) inhomogeneity of the common carotid artery (CCA) and the degree of stenosis of plaques in the internal carotid artery (ICA). Materials and Methods We included 240 patients with a recent ischemic stroke or transient ischemic attack and mild-to-moderate stenosis in the ipsilateral ICA. IMT inhomogeneity was extracted from B-mode ultrasound recordings. The degree of ICA stenosis was assessed on CT angiography according to the European Carotid Surgery Trial method. Patients were divided into groups with a low (≤ 2 %) and a high (> 2 %) IMT inhomogeneity scaled with respect to the local end-diastolic diameter. Results 182 patients had suitable CT and ultrasound measurements. Relative CCA-IMT inhomogeneity was similar for the symptomatic and asymptomatic side (difference: 0.02 %, p = 0.85). High relative IMT inhomogeneity was associated with a larger IMT (difference: 235 µm, p < 0.001) and larger degree of ICA stenosis (difference: 5 %, p = 0.023) which remained significant (p = 0.016) after adjustment for common risk factors. Conclusion Regardless of common risk factors, high relative CCA-IMT inhomogeneity is associated with a greater degree of ICA stenosis and is therefore indicative of atherosclerotic disease. The predictive value of CCA-IMT inhomogeneity for plaque progression and recurrence of cerebrovascular symptoms will be determined in the follow-up phase of PARISK.

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A practical means of evaluating the prognosis of acute pancreatitis : measurement of carotid artery intima-media thickness

Acta Gastro Enterologica Belgica ◽

10.51821/84.3.005 ◽

2021 ◽

Vol 84 (3) ◽

Author(s):

K Kurkcu ◽

B Kara ◽

A.S. Koc ◽

S.O. Keskek

Keyword(s):

Acute Pancreatitis ◽

Carotid Artery ◽

Internal Carotid Artery ◽

Organ Failure ◽

Internal Carotid ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Left Internal Carotid Artery ◽

Systemic Complications ◽

Media Thickness

Backgroung and study aims : Factors such as age, obesity, diabetes mellitus and hyperlipidemia that cause adverse prognosis in acute pancreatitis also cause an increase in carotid intima-media thickness. In this study, we aimed to investigate the usability of the measurement of carotid intima-media thickness, which is an easy to apply, cost-effective means of measurement applied to the patients, in predicting AP prognosis, apart from the criteria currently utilized to predict AP prognosis. Patient and methods : 101 patients diagnosed with acute pancreatitis were prospectively enrolled into the study. Right and left common carotid artery intima-media thickness, right and left internal carotid artery intima-media thickness were measured with ultrasonographic images performed within the first 24 hours of hospitalization. local or systemic complications and organ failure development were monitored in the follow-up of the patients. Results : After the ROC analysis was performed and the threshold value was determined. The the patients with main and internal carotid artery intima-media thickness above 0.775 mm were seen to have a more severe AP (p = 0.000). Local and systemic complications and organ failure were also more common in these patients. Conclusions : Measurement of carotid intima-media thickness is a non-invasive method that can be used to predict the prognosis in patients with acute pancreatitis at presentation.

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1.3 SPATIAL INHOMOGENEITIES IN INTIMA-MEDIA THICKNESS OF THE COMMON CAROTID ARTERY ARE ASSOCIATED WITH THE DEGREE OF STENOSIS IN THE INTERNAL CAROTID ARTERY

Artery Research ◽

10.1016/j.artres.2013.10.004 ◽

2013 ◽

Vol 7 (3-4) ◽

pp. 162

Author(s):

J. Steinbuch ◽

M.T.B. Truijman ◽

A.P.G. Hoeks ◽

W.H. Mess

Keyword(s):

Carotid Artery ◽

Internal Carotid Artery ◽

Common Carotid Artery ◽

Internal Carotid ◽

Intima Media Thickness ◽

Media Thickness ◽

The Common ◽

Spatial Inhomogeneities

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Carotid Intima‐Media Thickness and the Risk of Sudden Cardiac Death: The ARIC Study and the CHS

Journal of the American Heart Association ◽

10.1161/jaha.120.016981 ◽

2020 ◽

Vol 9 (19) ◽

Author(s):

Takeki Suzuki ◽

Wanmei Wang ◽

Anthony Wilsdon ◽

Kenneth R. Butler ◽

Selcuk Adabag ◽

...

Keyword(s):

Sudden Cardiac Death ◽

Carotid Artery ◽

Common Carotid Artery ◽

Cardiac Death ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Cardiovascular Health Study ◽

Media Thickness ◽

Increased Risk ◽

Aric Study

Background Sudden cardiac death (SCD) is associated with severe coronary heart disease in the great majority of cases. Whether carotid intima‐media thickness (C‐IMT), a known surrogate marker of subclinical atherosclerosis, is associated with risk of SCD in a general population remains unknown. The objective of this study was to investigate the association between C‐IMT and risk of SCD. Methods and Results We examined a total of 20 862 participants: 15 307 participants of the ARIC (Atherosclerosis Risk in Communities) study and 5555 participants of the CHS (Cardiovascular Health Study). C‐IMT and common carotid artery intima‐media thickness was measured at baseline by ultrasound. Presence of plaque was judged by trained readers. Over a median of 23.5 years of follow‐up, 569 participants had SCD (1.81 cases per 1000 person‐years) in the ARIC study. Mean C‐IMT and common carotid artery intima‐media thickness were associated with risk of SCD after adjustment for traditional risk factors and time‐varying adjustors: hazard ratios (HRs) with 95% CIs for fourth versus first quartile were 1.64 (1.15–2.63) and 1.49 (1.05–2.11), respectively. In CHS, 302 participants developed SCD (4.64 cases per 1000 person‐years) over 13.1 years. Maximum C‐IMT was associated with risk of SCD after adjustment: HR (95% CI) for fourth versus first quartile was 1.75 (1.22–2.51). Presence of plaque was associated with 35% increased risk of SCD: HR (95% CI) of 1.37 (1.13–1.67) in the ARIC study and 1.32 (1.04–1.68) in CHS. Conclusions C‐IMT was associated with risk of SCD in 2 biracial community‐based cohorts. C‐IMT may be used as a marker of SCD risk and potentially to initiate early therapeutic interventions to mitigate the risk.

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