Measuring carotid intima media thickness in other locations than the common carotid artery has low incremental prognostic value in the general population

2015 ◽  
Vol 241 (1) ◽  
pp. e163-e164
Author(s):  
K.A. Groenewegen ◽  
M.L. Bots ◽  
H.M. den Ruijter ◽  
S.A.E. Peters
PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e31086 ◽  
Author(s):  
Irene Marta Predazzi ◽  
Giuseppe Danilo Norata ◽  
Lucia Vecchione ◽  
Katia Garlaschelli ◽  
Francesca Amati ◽  
...  

2020 ◽  
Vol 9 (19) ◽  
Author(s):  
Takeki Suzuki ◽  
Wanmei Wang ◽  
Anthony Wilsdon ◽  
Kenneth R. Butler ◽  
Selcuk Adabag ◽  
...  

Background Sudden cardiac death (SCD) is associated with severe coronary heart disease in the great majority of cases. Whether carotid intima‐media thickness (C‐IMT), a known surrogate marker of subclinical atherosclerosis, is associated with risk of SCD in a general population remains unknown. The objective of this study was to investigate the association between C‐IMT and risk of SCD. Methods and Results We examined a total of 20 862 participants: 15 307 participants of the ARIC (Atherosclerosis Risk in Communities) study and 5555 participants of the CHS (Cardiovascular Health Study). C‐IMT and common carotid artery intima‐media thickness was measured at baseline by ultrasound. Presence of plaque was judged by trained readers. Over a median of 23.5 years of follow‐up, 569 participants had SCD (1.81 cases per 1000 person‐years) in the ARIC study. Mean C‐IMT and common carotid artery intima‐media thickness were associated with risk of SCD after adjustment for traditional risk factors and time‐varying adjustors: hazard ratios (HRs) with 95% CIs for fourth versus first quartile were 1.64 (1.15–2.63) and 1.49 (1.05–2.11), respectively. In CHS, 302 participants developed SCD (4.64 cases per 1000 person‐years) over 13.1 years. Maximum C‐IMT was associated with risk of SCD after adjustment: HR (95% CI) for fourth versus first quartile was 1.75 (1.22–2.51). Presence of plaque was associated with 35% increased risk of SCD: HR (95% CI) of 1.37 (1.13–1.67) in the ARIC study and 1.32 (1.04–1.68) in CHS. Conclusions C‐IMT was associated with risk of SCD in 2 biracial community‐based cohorts. C‐IMT may be used as a marker of SCD risk and potentially to initiate early therapeutic interventions to mitigate the risk.


1994 ◽  
Vol 14 (7) ◽  
pp. 1075-1079 ◽  
Author(s):  
P Pauciullo ◽  
A Iannuzzi ◽  
R Sartorio ◽  
C Irace ◽  
G Covetti ◽  
...  

2016 ◽  
Vol 38 (05) ◽  
pp. 523-529 ◽  
Author(s):  
Jeire Steinbuch ◽  
Anouk van Dijk ◽  
Floris Schreuder ◽  
Martine Truijman ◽  
Alexandra de Rotte ◽  
...  

Abstract Purpose Inhomogeneity of arterial wall thickness may be indicative of distal plaques. This study investigates the intra-subject association between relative spatial intima-media thickness (IMT) inhomogeneity of the common carotid artery (CCA) and the degree of stenosis of plaques in the internal carotid artery (ICA). Materials and Methods We included 240 patients with a recent ischemic stroke or transient ischemic attack and mild-to-moderate stenosis in the ipsilateral ICA. IMT inhomogeneity was extracted from B-mode ultrasound recordings. The degree of ICA stenosis was assessed on CT angiography according to the European Carotid Surgery Trial method. Patients were divided into groups with a low (≤ 2 %) and a high (> 2 %) IMT inhomogeneity scaled with respect to the local end-diastolic diameter. Results 182 patients had suitable CT and ultrasound measurements. Relative CCA-IMT inhomogeneity was similar for the symptomatic and asymptomatic side (difference: 0.02 %, p = 0.85). High relative IMT inhomogeneity was associated with a larger IMT (difference: 235 µm, p < 0.001) and larger degree of ICA stenosis (difference: 5 %, p = 0.023) which remained significant (p = 0.016) after adjustment for common risk factors. Conclusion Regardless of common risk factors, high relative CCA-IMT inhomogeneity is associated with a greater degree of ICA stenosis and is therefore indicative of atherosclerotic disease. The predictive value of CCA-IMT inhomogeneity for plaque progression and recurrence of cerebrovascular symptoms will be determined in the follow-up phase of PARISK.


1998 ◽  
Vol 141 (2) ◽  
pp. 307-314 ◽  
Author(s):  
Fredrik Karpe ◽  
Ulf de Faire ◽  
Michele Mercuri ◽  
M Gene Bond ◽  
Mai-Lis Hellénius ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document