MAXIMUM FLOW RATE — THE SINGLE UROFLOWMETRIC PARAMETER IN CLINICAL TRIALS FOR BENIGN PROSTATIC HYPERPLASIA?

1995 ◽  
Vol 2 (5) ◽  
pp. 322-325
Author(s):  
Yukio Homma ◽  
Chieko Imajo ◽  
Kazuki Kawabe
Keyword(s):  
Clinical Trials ◽  
Benign Prostatic Hyperplasia ◽  
Flow Rate ◽  
Maximum Flow ◽  
Prostatic Hyperplasia ◽  
Maximum Flow Rate

Predictive value of low maximum flow rate in benign prostatic hyperplasia

Urology ◽  
1986 ◽  
Vol 27 (6) ◽  
pp. 569-573 ◽  
Author(s):  
T. Dorflinger ◽  
R. Bruskewitz ◽  
K.M.-E. Jensen ◽  
P. Iversen ◽  
P.O. Madsen
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Flow Rate ◽  
Predictive Value ◽  
Maximum Flow ◽  
Prostatic Hyperplasia ◽  
Maximum Flow Rate

Elettrovaporizzazione endoscopica della prostata (TVP): Esperienza su 112 casi

1997 ◽  
Vol 64 (1_suppl) ◽  
pp. 85-89
Author(s):  
G.L. Berti ◽  
G.L Leidi ◽  
A. Raimoldi ◽  
L. Veneroni ◽  
V. Giola ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Surgical Technique ◽  
Flow Rate ◽  
Maximum Flow ◽  
Prostatic Hyperplasia ◽  
Maximum Flow Rate ◽  
Urine Retention ◽  
Post Operation ◽  
Mean Time ◽  
Actual Method

Transurethral electrovaporisation of the prostate (TVP) is one of the most recent techniques utilised as an alternative to TURP for the treatment of benign prostatic hyperplasia (BPH). This study reports our experience with TVP on 112 patients affected by BPH. All the patients had an adenoma equal or less than 40 grams in weight, maximum flow rate less than 10 ml per second or urine retention and PSA less than 4 mcg per litre. In all cases TVP was carried out without any complications during the operation (mean time 32 minutes) with no bleeding. 102 patients had the catheter removed after two days and 10 after 4 days. The maximum flow rate increased from 6.7 ml per second before the operation to 25.1 ml per second post operation. In 7 patients (6.2%) with unsatisfactory flow and/or with adenoma residue, it was necessary to perform a second TVP. 8 patients had temporary stress incontinence for 3 months after the operation, while one patient had permanent orthostatic incontinence. We can conclude that TVP is an easy technique to learn and has given the same clinical and urodynamic results as TURP, with negligible bleeding. The complication of temporary post operative incontinence in 7 patients and permanent incontinence in one patient, requires further studies to understand whether this is due to the surgical technique or to the actual method.

scholarly journals Clinical Significance of Intravesical Prostatic Protrusion in Patients with Benign Prostatic Hyperplasia

2015 ◽  
Vol 3 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Ghanshyam Sigdel ◽  
WK Belokar
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Symptom Score ◽  
Flow Rate ◽  
International Prostate Symptom Score ◽  
Prostate Volume ◽  
Maximum Flow ◽  
Prostatic Hyperplasia ◽  
Medical Sciences ◽  
Residual Urine ◽  
Intravesical Prostatic Protrusion

INTRODUCTION: Intravesical prostatic protrusion is a morphological change due to excessive growth of the median and lateral lobes of the prostate into the bladder in benign prostatic hyperplasia. It causes a 'ball-valve' type of obstruction during voiding. It is a useful parameter to assess the severity of the disease process, selection of treatment modality and its possible outcome in benign prostatic hyperplasia.MATERIAL AND METHODS: A prospective, non-randomized, observational study was carried out from January 2014 to June 2014 in the Department of Urology, College of Medical Sciences, Nepal. Total of 50 patients with benign prostatic hyperplasia were evaluated to assess the correlation of intravesical prostatic protrusion with international prostate symptom score, prostate volume, maximum flow rate and post void residual urine. Correlation between parameters of interest was quantified with Pearson correlation test.RESULTS: A positive correlation was demonstrated between intravesical prostatic protrusion, international prostate symptom score, prostate volume and post void residual urine. There was a negative correlation between intravesical prostatic protrusion and maximum flow rate.CONCLUSION: Intravesical prostatic protrusion is correlated with international prostate symptom score, prostate volume, maximum flow rate, and post void residual urine volume and hence can be used to assess the severity of benign prostatic hyperplasia.Journal of Universal College of Medical Sciences Vol. 3, No. 1, 2015: 6-10

scholarly journals THE CORRELATION OF INTERNATIONAL PROSTATE SYMPTOM SCORE (IPSS) WITH QMAX ON UROFLOWMETRY OF BENIGN PROSTATIC HYPERPLASIA (BPH) PATIENTS AT ABDUL WAHAB SJAHRANIE HOSPITAL IN SAMARINDA

2020 ◽  
Vol 7 (2) ◽  
pp. 85-91
Author(s):  
Nia Ramadhanurrosita ◽  
Boyke Soebhali ◽  
Hary Nugroho
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Flow Rate ◽  
Symptom Severity ◽  
Maximum Flow ◽  
Prostatic Hyperplasia ◽  
Benign Tumors ◽  
Cross Sectional ◽  
Urinary Tract Symptoms ◽  
Moderate Negative Correlation ◽  
Observational Design

Background: Benign prostatic hyperplasia (BPH) is one of the most common benign tumors on elderly man. BPH manifests as lower urinary tract symptoms (LUTS). To determine subjectively the symptom severity of LUTS, quantitatively, it was used a diagnostic tool called IPSS. However, IPSS individually is not enough in enforcement of definitive diagnosis man with LUTS. There were some other diagnostics tools used in diagnosing BPH, the other one is uroflowmetry examination that is objective. This research aims are to know the correlation between IPSS and Qmax on uroflowmetry in BPH patients at Abdul Wahab Sjahranie Hospital in Samarinda.Methods: This research is an analytic survey with observational design, cross sectional. The subject of this research is BPH patients with LUTS at Abdul Wahab Sjahranie Hospital in Samarinda on March until May 2019. Data is collected primarily through the IPSS’s questionnaire filled by the patient. Data flow rate obtained through uroflowmetry examination with emphasis on maximum flow rate (Qmax).Results: This research found that BPH is majorly found on group age 60-69 years (45%). IPSS with moderate symptom severity mostly found on patient (60%). Nocturia (90.5%) and incomplete emptying (85%) is the most frequent symptoms found. The analysis results showed that IPSS had a moderate negative correlation with Qmax on uroflowmetry (r = -0,567; p = 0,009).Conclusions: There was correlation between IPSS and Qmax on uroflowmetry of BPH patients at Abdul Wahab Sjahranie Hospital in Samarinda.

Lichen sclerosis–induced long segment anterior urethral stricture: The early outcome of one-stage repair using dorsolateral onlay buccal mucosa graft

2021 ◽  
pp. 039156032110033
Author(s):  
Atef Fathi ◽  
Omar Mohamed ◽  
Osama Mahmoud ◽  
Gamal A Alsagheer ◽  
Ahmed M Reyad ◽  
...  
Keyword(s):  
Success Rate ◽  
Urethral Stricture ◽  
Flow Rate ◽  
Urine Volume ◽  
Maximum Flow ◽  
Maximum Flow Rate ◽  
P Value ◽  
Onlay Graft ◽  
Voiding Symptoms ◽  
Stricture Recurrence

Background: Substitution urethroplasty using buccal mucosal grafts can be performed by several approaches including ventral onlay graft, dorsal onlay graft, or ventral urethrotomy with dorsal inlay graft. Our study aims to evaluate the surgical outcome of dorsolateral buccal mucosal graft for long segment anterior urethral stricture >6 cm in patients with Lichen sclerosus (LS). Methods: A retrospective study included patients who underwent repair for long segment anterior urethral stricture >6 cm due to LS between January 2013 and April 2019. All patients were followed-up at 3, 6, 9, and 12 months postoperatively and then yearly by clinical symptoms, uroflowmetry, and calculation of post-void residual urine volume. Retrograde urethrogram was requested for patients with voiding symptoms or decreased maximum flow rate. Stricture recurrence that required subsequent urethrotomy or urethroplasty was considered failure. The success rate and surgical complications were collected and analyzed. Results: Thirty patients were identified. The median age (range) was 39 (25–61) years and a median (range) stricture length was 8 (6–14) cm. Most of postoperative complications were of minor degree. The success rate at median follow-up of 15 (12–24) months was 86.5%. The median maximum flow rate increased significantly from 6 (2–11) ml/s preoperatively to 18 (range: 6–23) ml/s at the 6th month ( p value < 0.001). Conclusion: Dorsolateral buccal mucosal grafts urethroplasty for long anterior urethral stricture caused by LS has a high success rate and low risk of complications including stricture recurrence.

scholarly journals Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature

2020 ◽  
Vol 91 (4) ◽  
pp. 205-210
Author(s):  
Gian Maria Busetto ◽  
Francesco Del Giudice ◽  
Daniele D'Agostino ◽  
Daniele Romagnoli ◽  
Andrea Minervini ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Benign Prostatic Hyperplasia ◽  
Adverse Events ◽  
Clinical Efficacy ◽  
Critical Review ◽  
Reductase Inhibitor ◽  
Prostate Volume ◽  
Prostatic Hyperplasia ◽  
Urinary Flow ◽  
Efficacy And Safety

Background: Combination therapy with 5 alpha-reductase inhibitor (5-ARI) and alpha-blocker can be considered as a gold standard intervention for medical management of lower urinary tract symptoms related to benign prostatic hyperplasia (LUTS/BPH). On the other hand, 5-ARI monotherapy and in particular Finasteride alone is currently getting focus of attention especially due to lack of systematic reviews investigating efficacy outcomes and/or adverse events associated. Objectives: Aim of the present critical review was to analyze current knowledge of clinical efficacy and incidence of adverse events associated with 5-ARI treatment for LUTS/BPH. Materials and methods: A systematic review of clinical trials of the literature of the past 20 years was performed using database from PubMed, Cochrane Collaboration and Embase. A total of 8821 patients were included in this study and inclusion criteria for studies selection were: data from randomized clinical trials (RCTs) focusing their attention on the clinical role of Finasteride monotherapy for symptomatic BPH. Parameters of research included prostate specific antigen (PSA), prostate volume (PV), International Prostate Symptom Score (IPPS), postvoid residual urine (PVR), voiding symptoms of IPSS (voiding IPSS), maximum urinary flow rate (Qmax), and adverse events (AEs). Results: Overall 12 original articles were included and critically evaluated. Sample sizes of patient actively treated with finasteride varied from 13 to 1524 cases analyzed in a single study. Follow-up after treatments ranged from 3 to 54 months. The effect of finasteride in reducing prostate volume (PV) was moderate (standardized mean difference (SMD) effect between 0.5 to 0.8 for all trials evaluable) while the effect on IPSS score and Qmax was considered significant (SMD in the 0.2 to 0.5 variation range). No severe AEs and/or psychiatric disorders were retrieved among the studies. Sexual health dysfunctions were significantly influenced by finasteride therapy when compared with placebo treated patients. Conclusions: Although significant clinical benefits of finasteride monotherapy were demonstrated, the effective size of the available reports included in the analysis is limited. Additional head-to-head studies would be needed to re-evaluate clinical efficacy and safety of 5-ARI in combination or not with alpha blockers.

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