High Water Content Hydrophilic Contact Lenses

1974 ◽  
Vol 57 (10) ◽  
pp. 317-324
Author(s):  
DONALD F. EZEKIEL
1983 ◽  
Vol 17 (2) ◽  
pp. 261-274 ◽  
Author(s):  
S. Hosaka ◽  
H. Ozawa ◽  
H. Tanzawa ◽  
H. Ishida ◽  
K. Yoshimura ◽  
...  

2021 ◽  
Vol 80 (1) ◽  
Author(s):  
Rekha Hansraj ◽  
Siddeeqa Jhetam ◽  
Jared Haridutt ◽  
Tymon Lahner ◽  
Sthabile Madlala ◽  
...  

Background: Contact lens care regimens appear to be prescribed based on familiarity or by matching contact lens brands rather than consideration to efficacy.Aim: This study compared the effectiveness of multipurpose and peroxide cleaning solutions on low- and high-water content ionic and non-ionic soft contact lenses, in removing Pseudomonas aeruginosa (P. aeruginosa).Setting: The laboratory work was conducted by health science students in a graduate level programme in the microbiology laboratory at a university in south-eastern South Africa.Methods: A quantitative analytical experimental design was used. Four groups (labelled I, II, III and IV) of soft contact lenses, varied ionicity and water content were inoculated with P. aeruginosa and then exposed to three solutions containing antimicrobial ingredients, polyaminopropyl biguanide (Dymed), hydrogen peroxide (H2O2) and polyquaternium-1 (Polyquad). Each group contained 14 soft contact lenses, with the exception of Group III in which eight lenses were used. Saline served as the control. After 18 h, the remaining colony-forming units were counted using visual inspection as an indicator of efficacy against P. aeruginosa.Results: The solution containing H2O2 was found to be the most effective in removing P. aeruginosa from all Food and Drug Administration (FDA) groups of contact lenses whilst Dymed was found to be comparatively ineffective for this organism. Water content and ionicity had no effect on the efficacy of the solutions.Conclusion: Practitioners should consider the efficacy of the active ingredients against microorganisms when dispensing contact lens solutions, particularly for contact lens wearers at risk for P. aeruginosa infections.


2006 ◽  
Vol 38 (1) ◽  
pp. 39-42
Author(s):  
R. P. Bhatia ◽  
Kshama Panday ◽  
Rashmi Srivastava ◽  
Hitendra Singh Indolia

2020 ◽  
Vol 20 (9) ◽  
pp. 5609-5613
Author(s):  
Shengnan Wu ◽  
Chanhong Chung ◽  
Younghwan Kwon

We introduce a hydrophilic monosaccharide-containing 2-(α-D-mannopyranosyloxy)ethyl methacrylate (ManEMA) in this study to achieve more extended and comfortable wear silicone hydrogel contact lenses by increasing water content. Molecular structure of ManEMA contains a monosaccharide moiety with four hydroxyl groups, which provide a strong interaction with water. Therefore, the ManEMA-containing hydrogels are expected to have high water content. The structure of synthesized ManEMA is confirmed by 1H and 13C NMR spectroscopy. Contact lenses containing silicone polymers are coated with a monosaccharide-containingManEMA monomer with the help of plasma treatment and the use of 3-(trimethoxylsilyl)propyl methacrylate to provide an increased hydrophilicity. The feasibility of ManEMA as a surface modifier of silicone lenses is investigated in terms of water content and surface energy.


Biomaterials ◽  
1995 ◽  
Vol 16 (9) ◽  
pp. 685-690 ◽  
Author(s):  
Carla Renata Arciola ◽  
Maria Cristina Maltarello ◽  
Elisabetta Cenni ◽  
Arturo Pizzoferrato

2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.


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