Hydrogels as Antibacterial Biomaterials

2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Water Content ◽  
Oxygen Permeability ◽  
Structural Diversity ◽  
High Water ◽  
Clinical Applications ◽  
High Water Content ◽  
Biomedical Field

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.

Engineering of nanometer-sized cross-linked hydrogels for biomedical applications

2010 ◽  
Vol 88 (3) ◽  
pp. 173-184 ◽  
Author(s):  
Jung Kwon Oh
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Water Content ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
High Water ◽  
Delivery Systems ◽  
High Water Content ◽  
Surface Areas

Microgels/nanogels (micro/nanogels) are promising drug-delivery systems (DDS) because of their unique properties, including tunable chemical and physical structures, good mechanical properties, high water content, and biocompatibility. They also feature sizes tunable to tens of nanometers, large surface areas, and interior networks. These properties demonstrate the great potential of micro/nanogels for drug delivery, tissue engineering, and bionanotechnology. This mini-review describes the current approaches for the preparation and engineering of effective micro/nanogels for drug-delivery applications. It emphasizes issues of degradability and bioconjugation, as well as loading/encapsulation and release of therapeutics from customer-designed micro/nanogels.

A high water-content and high elastic dual-responsive polyurethane hydrogel for drug delivery

2015 ◽  
Vol 3 (42) ◽  
pp. 8401-8409 ◽  
Author(s):  
Jinze Li ◽  
Li Ma ◽  
Guangxin Chen ◽  
Zheng Zhou ◽  
Qifang Li
Keyword(s):  
Drug Delivery ◽  
Water Content ◽  
Wound Dressing ◽  
High Water ◽  
High Water Content ◽  
Dual Responsive ◽  
High Elasticity ◽  
Polyurethane Hydrogel

A light- and reductant-responsive hydrogel with high elasticity can be used for drug delivery and wound dressing.

High-water-content graphene oxide/polyvinyl alcohol hydrogel with excellent mechanical properties

2014 ◽  
Vol 2 (27) ◽  
pp. 10508-10515 ◽  
Author(s):  
Yifu Huang ◽  
Mingqiu Zhang ◽  
Wenhong Ruan
Keyword(s):  
Mechanical Properties ◽  
Graphene Oxide ◽  
Polyvinyl Alcohol ◽  
Water Content ◽  
High Water ◽  
High Water Content ◽  
Cross Linking ◽  
Freeze Thaw

Boron-cross-linked graphene oxide/polyvinyl alcohol (B-GO/PVA) hydrogels with high-water-content and excellent mechanical properties are prepared by freeze/thaw and boron cross-linking methods.

Hydrogels for tissue engineering and regenerative medicine

2014 ◽  
Vol 2 (33) ◽  
pp. 5319-5338 ◽  
Author(s):  
John A. Hunt ◽  
Rui Chen ◽  
Theun van Veen ◽  
Nicholas Bryan
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Water Content ◽  
Drug Carrier ◽  
High Water ◽  
High Water Content ◽  
Injectable Hydrogels ◽  
Surgical Implantation

Injectable hydrogels have become an incredibly prolific area of research in the field of tissue engineering and regenerative medicine, because of their high water content, mechanical similarity to natural tissues, and ease of surgical implantation, hydrogels are at the forefront of biomedical scaffold and drug carrier design.

An in situ poly(carboxybetaine) hydrogel for tissue engineering applications

2017 ◽  
Vol 5 (2) ◽  
pp. 322-330 ◽  
Author(s):  
Hsiu-Wen Chien ◽  
Jiashing Yu ◽  
Shing Tak Li ◽  
Hsin-Yu Chen ◽  
Wei-Bor Tsai
Keyword(s):  
Tissue Engineering ◽  
Water Content ◽  
Three Dimensional ◽  
High Water ◽  
Tissue Scaffolds ◽  
High Water Content ◽  
Engineering Applications

Hydrogels provide three-dimensional (3D) frames with tissue-like elasticity and high water content for tissue scaffolds.

Microwave-Induced Thermoacoustic Imaging for Embedded Explosives Detection in High-Water Content Medium

2019 ◽  
Vol 67 (7) ◽  
pp. 4803-4810 ◽  
Author(s):  
Xiong Wang ◽  
Tao Qin ◽  
Yexian Qin ◽  
Ahmed H. Abdelrahman ◽  
Russell S. Witte ◽  
...  
Keyword(s):  
Water Content ◽  
High Water ◽  
Explosives Detection ◽  
High Water Content ◽  
Thermoacoustic Imaging

scholarly journals Biomedical application of photo-crosslinked gelatin hydrogels

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Lei Xiang ◽  
Wenguo Cui
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Application ◽  
Biomedical Field ◽  
Or Gene ◽  
Tunable Mechanical Properties ◽  
Bio Compatibility ◽  
Regeneration Of Bone ◽  
Development Prospects

Abstract During the past decades, photo-crosslinked gelatin hydrogel (methacrylated gelatin, GelMA) has gained a lot of attention due to its remarkable application in the biomedical field. It has been widely used in cell transplantation, cell culture and drug delivery, based on its crosslinking to form hydrogels with tunable mechanical properties and excellent bio-compatibility when exposed to light irradiation to mimic the micro-environment of native extracellular matrix (ECM). Because of its unique biofunctionality and mechanical tenability, it has also been widely applied in the repair and regeneration of bone, heart, cornea, epidermal tissue, cartilage, vascular, peripheral nerve, oral mucosa, and skeletal muscle et al. The purpose of this review is to summarize the recent application of GelMA in drug delivery and tissue engineering field. Moreover, this review article will briefly introduce both the development of GelMA and the characterization of GelMA. Finally, we discuss the challenges and future development prospects of GelMA as a tissue engineering material and drug or gene delivery carrier, hoping to contribute to accelerating the development of GelMA in the biomedical field. Graphical abstract

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