Role of human papillomavirus in the development of epithelial ovarian neoplasms in Italian women

2008 ◽  
Vol 34 (2) ◽  
pp. 210-217 ◽  
Author(s):  
Giovanna Giordano ◽  
Tiziana D'Adda ◽  
Letizia Gnetti ◽  
Elisabetta Froio ◽  
Carla. Merisio ◽  
...  
2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Mario Preti ◽  
John Charles Rotondo ◽  
Dana Holzinger ◽  
Leonardo Micheletti ◽  
Niccolò Gallio ◽  
...  

2021 ◽  
Vol 9 (5) ◽  
pp. 891
Author(s):  
Takashi Hatano ◽  
Daisuke Sano ◽  
Hideaki Takahashi ◽  
Nobuhiko Oridate

The incidence of oropharyngeal cancer (OPC) is increasing remarkably among all head and neck cancers, mainly due to its association with the human papillomavirus (HPV). Most HPVs are eliminated by the host’s immune system; however, because HPV has developed an effective immune evasion mechanism to complete its replication cycle, a small number of HPVs are not eliminated, leading to persistent infection. Moreover, during the oncogenic process, the extrachromosomal HPV genome often becomes integrated into the host genome. Integration involves the induction and high expression of E6 and E7, leading to cell cycle activation and increased genomic instability in the host. Therefore, integration is an important event in oncogenesis, although the associated mechanism remains unclear, especially in HPV-OPC. In this review, we summarize the current knowledge on HPV-mediated carcinogenesis, with special emphasis on immune evasion and integration mechanisms, which are crucial for oncogenesis.


2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Yi Zhou ◽  
Jinyuan Li ◽  
Yuting Ji ◽  
Ming Ren ◽  
Bo Pang ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0116618 ◽  
Author(s):  
Suzette M. Matthijsse ◽  
Joost van Rosmalen ◽  
Jan A. C. Hontelez ◽  
Roel Bakker ◽  
Inge M. C. M. de Kok ◽  
...  

Intervirology ◽  
2010 ◽  
Vol 53 (6) ◽  
pp. 417-425 ◽  
Author(s):  
Maria Antonia De Francesco ◽  
Franco Gargiulo ◽  
Claudio Schreiber ◽  
Giuseppe Ciravolo ◽  
Federica Salinaro ◽  
...  

2007 ◽  
Vol 86 (1) ◽  
pp. 94-98 ◽  
Author(s):  
José Eleutério Jr ◽  
Paulo César Giraldo ◽  
Ana Katherine Gonçalves ◽  
Diane Isabelle Magno Cavalcante ◽  
Francisco Valdeci de Almeida Ferreira ◽  
...  

1991 ◽  
Vol 25 (4) ◽  
pp. 698-705 ◽  
Author(s):  
Matthew Brett Quan ◽  
Ronald Leonard Moy
Keyword(s):  

2018 ◽  
Vol 122 ◽  
pp. 92-97 ◽  
Author(s):  
Giorgio Bogani ◽  
Umberto Leone Roberti Maggiore ◽  
Mauro Signorelli ◽  
Fabio Martinelli ◽  
Antonino Ditto ◽  
...  

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