The management of neurogenic bladder and quality of life in spinal cord injury

BACKGROUD: Spinal cord injury (SCI) is damage that can cause a temporary or permanent change in spinal cord functions AIM: This work evaluates clinical signs, mental signs, and quality of life (QoL) after autologous adipose-derived stem cells (ADSCs) transplantation to treat acute spinal cord injury (SCI). MATERIAL AND METHODS: In this study, 47 SCI patients were recruited and divided into two groups: intervention and control. ADSCs were isolated and cultured under the cell culture quality control procedure. All patients in both groups underwent neurosurgery with or without ADSC transplantation. The recovery regarding neurological muscle, QoL, neurogenic bladder, and mental improvement was assessed after transplantation. RESULTS: All patients had improved in terms of motor function, bladder function, and daily living. No patients reported any side effect. MRI imaging showed significant changes in the lesion length of the spinal canal and the thickening of the spinal cord. Mental improvement was highest at six months after transplantation and lowest at one month after transplantation. The proportion of patients whose quality of life improved after treatment was 100%, while 80% of patients were satisfied with treatment outcomes. CONCLUSIONS: Thus, our data suggested that ADSCs transplantation was safe and effective for the treatment of SCI patients. Neurological muscle and neurogenic bladder were improved significantly after transplantation.

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Up-to-date review reporting the technological details of devices used in the management of neurogenic bladder in post spinal cord injury patients

Romanian Journal of Medical Practice ◽

10.37897/rjmp.2015.2.3 ◽

2015 ◽

Vol 10 (2) ◽

pp. 102-106

Author(s):

Aura SPINU ◽

◽

Cristina DAIA ◽

Monica HARAS ◽

Aurelian ANGHELESCU ◽

...

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Neurogenic Bladder ◽

Gold Standard ◽

Lower Urinary Tract ◽

The Past ◽

Cord Injury ◽

Lower Urinary

In the past years, a major cause of invalidity and death in post spinal cord injury (SCI) patients with neurogenic bladder (NB) was the renal failure. Since our ability to manage the dysfunction of NB has improved, the morbidity/mortality in these individuals significantly decreased. The aims in NB management are to protect the upper and lower urinary tract and to improve the quality of life (QoL) of these individuals. The insertion and removal of the catheter many times a day, to empty the bladder is called intermittent catheterization and it is considered the „gold standard“ in the NB management. Nowadays, there are available many types of catheters, materials and techniques: non-coated catheters, gel-coated catheters, hydrophilic catheters, glycerine based catheters. The choice of a catheter should be made on an individual analyse, according to gender, age, level of injury, functional status, urethral sensibility, or the circumstances the IC is needed (so, a patient may need a type of catheter at home and another one outside).

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Coping and Quality of Life in subjects with Spinal Cord Injury

PsycEXTRA Dataset ◽

10.1037/e572992012-489 ◽

2010 ◽

Author(s):

A. Teixeira ◽

F. Machado

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Cord Injury

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Long term outcome of functional independence and quality of life after traumatic SCI in Germany

Spinal Cord ◽

10.1038/s41393-021-00659-9 ◽

2021 ◽

Author(s):

Florian Möller ◽

Rüdiger Rupp ◽

Norbert Weidner ◽

Christoph Gutenbrunner ◽

Yorck B. Kalke ◽

...

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Functional Independence ◽

Term Outcome ◽

Long Term Outcome ◽

Cord Injury ◽

Over Time

Abstract Study design Multicenter observational study. Objective To describe the long-term outcome of functional independence and quality of life (QoL) for individuals with traumatic and ischemic SCI beyond the first year after injury. Setting A multicenter study in Germany. Methods Participants of the European multicenter study about spinal cord injury (EMSCI) of three German SCI centers were included and followed over time by the German spinal cord injury cohort study (GerSCI). Individuals’ most recent spinal cord independence measure (SCIM) scores assessed by a clinician were followed up by a self-report (SCIM-SR) and correlated to selected items of the WHO short survey of quality of life (WHO-QoL-BREF). Results Data for 359 individuals were obtained. The average time passed the last clinical SCIM examination was 81.47 (SD 51.70) months. In total, 187 of the 359 received questionnaires contained a completely evaluable SCIM-SR. SCIM scores remained stable with the exception of reported management of bladder and bowel resulting in a slight decrease of SCIM-SR of −2.45 points (SD 16.81). SCIM-SR scores showed a significant correlation with the selected items of the WHO-QoL-BREF (p < 0.01) with moderate to strong influence. Conclusion SCIM score stability over time suggests a successful transfer of acquired independence skills obtained during primary rehabilitation into the community setting paralleled by positively related QoL measurements but bladder and bowel management may need special attention.

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