Abstracts: Polyoxyethylene/polyoxypropylene dimethyl ether improves the structure of intercellular lipids in SDS-induced dry skin

2010 ◽  
Vol 32 (5) ◽  
pp. 394-394
Author(s):  
E. Yagi ◽  
T. Ohmori ◽  
K. Sakamoto
Keyword(s):  
Dimethyl Ether ◽  
Dry Skin ◽  
Intercellular Lipids

scholarly journals Electron Microscopic Observations of Stratum Corneum Intercellular Lipids in Normal and Atopic Dogs

2001 ◽  
Vol 38 (6) ◽  
pp. 720-723 ◽  
Author(s):  
A. O. Inman ◽  
T. Olivry ◽  
S. M. Dunston ◽  
N. A. Monteiro-Riviere ◽  
H. Gatto
Keyword(s):  
Stratum Corneum ◽  
Transepidermal Water Loss ◽  
Dry Skin ◽  
Electron Microscopic ◽  
Transmission Electron ◽  
Stratum Corneum Lipid ◽  
Structural Differences ◽  
Stratum Corneum Lipids ◽  
Intercellular Lipids ◽  
Intercellular Lipid

The barrier function of mammalian skin is maintained by intercellular stratum corneum lipids. In human patients with atopic dermatitis, an abnormal lipid barrier results in dry skin and increased transepidermal water loss. At this time, it is not known if a defective lipid barrier is present in atopic dogs. Normal and atopic canine skin were postfixed in ruthenium tetroxide and studied using transmission electron microscopy to determine structural differences within stratum corneum lipids. Intercellular lipid lamellae were graded on a semiquantitative scale. The deposition of stratum corneum lipid lamellae in atopic canine skin appeared markedly heterogeneous compared with that seen in normal canine skin. When present, the lamellae often exhibited an abnormal structure. The continuity and thickness of the intercellular lipid lamellae were significantly less in nonlesional atopic than in normal canine skin. These preliminary observations suggest that the epidermal lipid barrier is defective in atopic canine skin. Additional studies are needed to further characterize the biochemical defect and to possibly correct it with nutritional and/or pharmacologic intervention.

Changes in corneocyte element concentrations occur in skin inner stratum corneum

1990 ◽  
Vol 48 (2) ◽  
pp. 146-147
Author(s):  
R. R. Warner
Keyword(s):  
Stratum Corneum ◽  
Human Skin ◽  
Element Concentration ◽  
Skin Barrier ◽  
Barrier Properties ◽  
Brick Wall ◽  
Inorganic Elements ◽  
Dry Skin ◽  
Skin Biopsies ◽  
Intercellular Lipid

Keratinocytes undergo maturation during their transit through the viable layers of skin, and then abruptly transform into flattened, anuclear corneocytes that constitute the cellular component of the skin barrier, the stratum corneum (SC). The SC is generally considered to be homogeneous in its structure and barrier properties, and is often shown schematically as a featureless brick wall, the “bricks” being the corneocytes, the “mortar” being intercellular lipid. Previously we showed the outer SC was not homogeneous in its composition, but contained steep gradients of the physiological inorganic elements Na, K and Cl, likely originating from sweat salts. Here we show the innermost corneocytes in human skin are also heterogeneous in composition, undergoing systematic changes in intracellular element concentration during transit into the interior of the SC.Human skin biopsies were taken from the lower leg of individuals with both “good” and “dry” skin and plunge-frozen in a stirred, cooled isopentane/propane mixture.

Pyrotechnic Residues in Gunshot Residue Analysis

1985 ◽  
Vol 43 ◽  
pp. 128-129
Author(s):  
H. M. Sagara ◽  
S. A. Schliebe ◽  
M. C. Kong
Keyword(s):  
Law Enforcement ◽  
Residue Analysis ◽  
Gunshot Residue ◽  
Particle Analysis ◽  
Dry Skin ◽  
X Ray ◽  
Skin Cells ◽  
Smokeless Powder ◽  
Carbon Coated ◽  
Detailed List

Particle analysis by scanning electron microscopy with energy-dispersive x- ray analysis is one of the current methods used in crime laboratories to aid law enforcement in identifying individuals who have recently fired or handled a firearm. During the discharge of a firearm, the high pressure caused by the detonation of the cartridge materials forces a portion of the generated gases through leaks in the firing mechanism of the weapon. These gases contain residues of smokeless powder, primer mixture, and contributions from the projectile itself. The condensation of these hot gases form discrete, micrometer-sized particles, which can be collected, along with dry skin cells, salts, and other hand debris, from the hands of a shooter by a simple adhesive lift technique. The examination of the carbon-coated adhesive lifts consist of time consuming systematic searches for high contrast particles of spherical morphology with the characteristic elemental composition of antimony, barium and lead. A detailed list of the elemental compositions which match the criteria for gunshot residue are discussed in the Aerospace report.

Rancang Bangun Aplikasi Sistem Pakar untuk Menangani Masalah Kecantikan pada Wajah Menggunakan Metode Decision Tree

2014 ◽  
Vol 6 (1) ◽  
pp. 9-14
Author(s):  
Stefanie Sirapanji ◽  
Seng Hansun
Keyword(s):  
Decision Tree ◽  
Uneven Distribution ◽  
Dry Skin ◽  
Average Accuracy ◽  
Accuracy Level ◽  
Index Terms ◽  
Decision Tree Method ◽  
Tree Method

Beauty is a precious asset for everyone. Everyone wants to have a healthy face. Unfortunately, there are always those problems that pops out on its own. For example, acnes, freckles, wrinkles, dull, oily and dry skin. Therefore, nowadays, there are a lot of beauty clinics available to help those who wants to solve their beauty troubles. But, not everyone can enjoy the facilities of those beauty clinics, for example those in the suburbs. The uneven distribution of doctors and the expensive cost of treatments are some of the reasons. In this research, the system that could help the patients to find the solution of their beauty problems is built. The decision tree method is used to take decision based on the shown schematic. Based on the system’s experiment, the average accuracy level hits 100%. Index Terms–Acnes, Decision Tree, Dry Skin, Dull, Facial Problems, Freckles, Wrinkles, Oily Skin, Eexpert System.

Dermatology in primary care: an audit of the proportion of patients who present to general practice with a dermatological problem that could be self-managed

2020 ◽  
Vol 70 (suppl 1) ◽  
pp. bjgp20X711053
Author(s):  
Luamar Dolfini ◽  
Yogesh Patel
Keyword(s):  
Primary Care ◽  
General Practice ◽  
Acne Vulgaris ◽  
Clinical Information ◽  
Electronic Record ◽  
Self Management ◽  
Considerable Proportion ◽  
Dry Skin ◽  
Record System ◽  
Common Skin

BackgroundA considerable proportion of GPs’ workload is dermatological. It is important to investigate what common skin conditions encountered in primary care can be self-managed, in an effort to alleviate the burden on primary care.AimThe purpose of the audit was to identify the proportion of consultations that are dermatological in nature and analyse potential for self-management by patients.MethodData was collected using the patient electronic record system (EMIS) in general practice. A search was made for all consultations from the 17 April to 15 May 2019, which included all new presenting complaints that were dermatological in nature. The criteria for self-management included advising over the counter (OTC) medication or reassurance. On the other hand, a case was deemed not self-manageable if prescription only medication (POM) was prescribed or if a referral to dermatology was made.ResultsThere were a total of 2175 consultations, where 246 (11.31%) cases were dermatological. Of the 246, 80 cases (32.5%) could be self-managed. There were 46 different dermatological presenting complaints of which the 5 most common included: rash (51 cases), dermatitis (44 cases), acne vulgaris (13 cases), moles (12 cases), dry skin (11 cases). None of the acne or moles cases could be self-managed, whereas 23%, 68.2%, 72.7% of rashes, dermatitis, and dry skin cases, respectively, could be self-managed.ConclusionCertain dermatological conditions have more potential for self-management than others. Research into teledermatology as a means of addressing patient concern and providing clinical information is important in order to reduce unnecessary consultations.

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