Umbilical artery reactivity and ultrastructural changes in pregnancy-induced hypertension and other complicated pregnancies

1987 ◽  
Vol 7 (6) ◽  
pp. 493-502 ◽  
Author(s):  
F. D. Johnstone ◽  
L. Ugaily-Thulesius ◽  
O. Thulesius ◽  
A. N. Nasrat
Keyword(s):  
Umbilical Artery ◽  
Ultrastructural Changes ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
In Pregnancy

scholarly journals Doppler ultrasound of umbilical artery in prediction of fetal outcome in pregnancy induced hypertension Sudanese population

2019 ◽  
Vol 8 (1) ◽  
pp. 96
Author(s):  
Rihab A. Yousif ◽  
Awadia G. Suliman ◽  
Raga A. Aburaida ◽  
Ibrahim M. Daoud ◽  
Naglaa E. Mohammed
Keyword(s):  
Flow Velocity ◽  
Umbilical Artery ◽  
Fetal Outcome ◽  
Fetal Mortality ◽  
Pregnancy Induced Hypertension ◽  
Diastolic Flow ◽  
Induced Hypertension ◽  
The Mean ◽  
Doppler Indices ◽  
In Pregnancy

The pregnancy induced hypertension increase the fetal mortality and morbidity and the using of Doppler umbilical artery indices decrease the fetal mortality and morbidity however, there is few complete data about the most frequently altered Doppler US parameters to predict fetal outcome in pregnancy induced hypertension . Methods This ia cohort prospective study done in two hundred and six women of second and third trimester presenting to antenatal clinic in Soba University Hospital at the department of Obstetrics & Gynecology, in the fetus unit and critical pregnancy in the period From June 2008 to April 2013 to assess the Doppler indices of umbilical artery in pregnancy induced hypertension for prediction of prenatal outcome; 105 pregnancy induced hypertension patients and 101 women with uneventful pregnancies as normal control group included in this study . Baseline investigations and color Doppler of umbilical artery were done. Statistical analysis of data were done using SPSS, Receiver Operating Characteristic (ROC) curve analysis was performed and the area under the curve (AUC) used to determine sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of umbilical artery Doppler indices to predict fetal outcome.Results The study determine that there was significant difference in Doppler indices in PIH and control group ( p<0.01, the mean indices of umbilical artery is higher in PIH group compared with normal pregnancy group , the mean different of S/D ratio was 0.40, mean difference of RI was 0.06 and the mean different of PI index was 0.16, high percentage of adverse fetal outcome had been reported in in Pregnancy Induced Hypertension group than in control , which was more in absent and reversed flow velocity in umbilical artery in Pregnancy Induced Hypertension compared with group of Pregnancy Induced Hypertension with present end diastolic flow velocity. Systolic/Diastolic ratio was most accurate in predicting adverse outcome in pregnancy induced hypertension patients, followed by the Pulastility index then the Resistance index (75%, 66% and 57% respectively).ConclusionThis study concluded that pregnancy induced hypertension leads to worsen placental insufficiently, which appears on the higher Doppler indices of umbilical artery to PIH patients when compared with normal pregnancy. A low diastolic flow and higher indices characterized the pregnancies with abnormal outcomes. Doppler of the umbilical artery was useful to predict fetal well being in PIH patients, high percentage of adverse fetal outcome had been reported in absent and reversed end diastolic flow velocity in umbilical artery compared with group of present flow velocity.

scholarly journals A prospective observational study to analyse the relationship between fundus changes in pregnancy induced hypertension with visual impairment and its reversibility

2021 ◽  
Vol 10 (11) ◽  
pp. 4272
Author(s):  
Vinitha Dharmalingam ◽  
R. Kala
Keyword(s):  
Observational Study ◽  
Visual Impairment ◽  
Prospective Observational Study ◽  
Hypertensive Retinopathy ◽  
Pregnancy Induced Hypertension ◽  
Choroidal Ischemia ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
The Relationship ◽  
In Pregnancy

Background: Irreversible visual impairment and morbidity are associated with pregnancy induced hypertension. It causes pathological changes in vascularity of placenta, kidney and brain along with two major pathological types of changes in fundus namely arteriolar vasospasm and permeability changes in vascular endothelium. The aim of our study was to analyse the relationship between fundus changes in pregnancy induced hypertension with visual impairment and its reversibility.Methods: A prospective observational study done on pregnant women with any grade of pregnancy induced hypertension with recent visual impairment from 24 completed weeks of pregnancy.Results: Out of 75 patients with PIH, all the patients had varying degree of fundus changes in one or both eyes. In 150 eyes of the 75 patients, 86 (57.30%) eyes had isolated arteriolar vasospasm, 14 (9.33%) had grade III hypertensive retinopathy, 4 (2.66%) had grade IV hypertensive retinopathy, 30 (20%) had macular oedema, 4 (2.66%) had central serous chorioretinopathy, 2 (1.33%) had vascular occlusion, 2 (2.66%) eyes had normal fundus with cortical blindness, 2 (2.66%) had exudative retinal detachment, 6 (4%) eyes had normal fundus with changes in the other eye.Conclusions: Out of 75 patients, 7 (9.3%) patients had irreversible loss of vision, 3 (42.85%) due to arteriolar vasospasm, and 4 (57.15%) due to choroidal ischemia. Among the 4 patients with choroidal ischemia, 3 (75%) were in the group of eclampsia and 1 (25%) in gestational hypertension.

scholarly journals PREVALENCE OF FUNDUS CHANGES IN PREGNANCY INDUCED HYPERTENSION – A CLINICAL STUDY

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Manpreet Kour ◽  
Vijayta Gupta
Keyword(s):  
Clinical Study ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
Severity Of The Disease ◽  
In Pregnancy

To evaluate prevalence of fundus changes in Pregnancy Induced Hypertension (PIH) and to find the correlation of the findings with the levels of hypertension and with the severity of the disease.

scholarly journals FUNDUS CHANGES IN PREGNANCY INDUCED HYPERTENSION: A CLINICAL STUDY

2015 ◽  
Vol 04 (09) ◽  
pp. 1552-1562 ◽  
Author(s):  
Rama Bharathi N ◽  
Ramya Seetham Raju N ◽  
Krishna Prasad P ◽  
Raju R S N ◽  
Premalatha Premalatha ◽  
...  
Keyword(s):  
Clinical Study ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
In Pregnancy

scholarly journals A Study on Fundus changes in Pregnancy-induced hypertension: A Four-year Observation

2021 ◽  
Vol 4 (2) ◽  
pp. 162
Author(s):  
Elluru Pandu Rangaiah ◽  
Madhavi Latha Gangisetty ◽  
Sandhya K ◽  
Latha A ◽  
Meena Syed
Keyword(s):  
Pregnant Women ◽  
Pregnancy Termination ◽  
Renal Diseases ◽  
Hypertensive Retinopathy ◽  
Pregnancy Induced Hypertension ◽  
Important Indicator ◽  
Positive Correlation ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
In Pregnancy

Introduction: Hypertensive disorders complicate 5-10% in all pregnant and together form the deadly triad and hemorrhage and heart disease that contribute greatly to maternal morbidity or mortality. This study aims to identify retinal changes in pregnancy-induced hypertension and analyze the association between retinal changes and hypertension severity. Method: A total of 100 pregnant admitted with pregnancy-induced hypertension(PIH) were included. Patients with pre-existing hypertension, diabetes mellitus, and renal diseases were excluded from the study. The vision, anterior segment, and Fundus were examined. Result: Higher number of PIH were recorded in the 21-30 years age group. Fifty-four pregnant women suffered from mild preeclampsia, 40 pregnant women with severe preeclampsia, and six pregnant women with eclampsia with seizures. 41% of pregnant had normal fundus, and 24% of pregnant had hypertensive retinopathy. Whereas grade 2,3, and 4 retinopathy was observed in 22%, 6%, and 2% of pregnant women. Two percent of pregnants had macular edema, and 3% had central serous retinopathy. No association was observed between the fundus findings with age/gravida. Whereas a significant positive correlation was observed between the fundus findings and hypertension severity (P < 0.001). Conclusion: Overall, 54% of pregnants were recorded with hypertensive retinopathy. A positive correlation was observed between fundus changes with the hypertension severity. This study reports the importance of routine fundus examination in pregnant with hypertension. Retinal change during pregnancy is an important indicator to decide the pregnancy termination or any other opt.

scholarly journals Prevalence of Hypertensive Retinopathy Changes in Pregnancy induced Hypertension

2015 ◽  
Vol 2 (10) ◽  
pp. 182-185
Author(s):  
Anil kumar Bhupally ◽  
◽  
Sindu Sulekha ◽  
Rama Devi E ◽  
Swathi M ◽  
...  
Keyword(s):  
Hypertensive Retinopathy ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
In Pregnancy
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