Breast Molecular Imaging: A Retrospective Review of One Institutions Experience with this Modality and Analysis of its Potential Role in Breast Imaging Decision Making

2012 ◽  
Vol 18 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Emily Siegal ◽  
Elizabeth Angelakis ◽  
Patricia Morris ◽  
Edward Pinkus
2019 ◽  
Vol 33 (4) ◽  
pp. 44-53
Author(s):  
R. Yu. Vernadsky ◽  
A. A. Medvedeva ◽  
E. Yu. Garbukov ◽  
V. I. Chernov ◽  
E. M. Slonimskaia

Molecular imaging is a multimodal discipline for visualizing biological processes at the subcellular level in vivo. These diagnostic methods could be potentially used for screening and staging of cancer as well as for monitoring of treatment. Formerly, mostly anatomical information played key role in medical visualization. Now, molecular visualization allows improving diagnostic parameters of standard diagnostic methods. Molecular imaging allows not only for localization of tumor, but also for visualization of biological processes that influence tumor behavior and response to therapy. This review reflects the potential role of radionuclide methods and radiopharmaceuticals in diagnostic and assessment of tumor response. The paper covers indications and capabilities of dedicated nuclear breast imaging systems such as breast-specific g-imaging and positron-emission mammography. The accuracy of different methods was analyzed. The analysis showed that new technological solutions allow to significantly increase informativeness of examinations through improved spatial resolution compared to whole-body imaging cameras. Molecular imaging is useful for neoadjuvant chemotherapy response monitoring and is highly sensitive for prediction of non-responsiveness during treatment of breast cancer. The sensitivity of molecular breast imaging is comparable with that of magnetic resonance imaging, but has higher specificity. Molecular imaging may play a great potential role in the diagnostic algorithm for breast cancer.


2013 ◽  
Vol 29 (3) ◽  
pp. 277-290 ◽  
Author(s):  
Bridget Bwalya Umar

AbstractDifferent theories have been posited that try to explain the decision-making process of smallholders especially regarding the adoption of new technologies or new agricultural techniques. The objective of this paper is to review and re-assess the dominant household production theories to explain the decision making of smallholders practicing conservation agriculture (CA) in the southern, eastern, and central provinces of Zambia. It also discusses the potential role of CA toward economic development. It finds that the CA smallholders studied did not aim to maximize profits but tried to secure household consumption from their own production before any other considerations in risky and uncertain environments. Their response to economic incentives was contingent on minimizing risks associated with securing a minimum level of livelihood and investing into local forms of insurance. This paper concludes that the ability for CA to contribute to rural livelihoods and economic development would depend on how adequately the factors that hinder smallholder agricultural development in general are addressed.


1994 ◽  
Vol 9 (2) ◽  
pp. 58-63 ◽  
Author(s):  
Gilbert M. Goldman ◽  
Thyyar M. Ravindranath

Critical care decision-making involves principles common to all medical decision-making. However, critical care is a remarkably distinctive form of clinical practice and therefore it may be useful to distinguish those elements particularly important or unique to ICU decision-making. The peculiar contextuality of critical care decision-making may be the best example of these elements. If so, attempts to improve our understanding of ICU decision-making may benefit from a formal analysis of its remarkable contextual nature. Four key elements of the context of critical care decisions can be identified: (1) costs, (2) time constraints, (3) the uncertain status of much clinical data, and (4) the continually changing environment of the ICU setting. These 4 elements comprise the context for the practice of clinical judgment in the ICU. The fact that intensivists are severely constrained by teh context of each case has important ramifications both for practice and for retrospective review. During retrospective review, the contextual nature of ICU judgment may be unfairly neglected by ignoring one or more of the key elements. Such neglect can be avoided if intensivists demand empathetic evaluation from reviewers.


2020 ◽  
Vol 33 (2) ◽  
pp. 233
Author(s):  
Luciana Lerendegui ◽  
Jimena Esnaola ◽  
Pablo Lobos ◽  
Juan Moldes ◽  
Francisco de Badiola ◽  
...  

2010 ◽  
Vol 13 (2) ◽  
pp. 232-238 ◽  
Author(s):  
Stephanie M. W. Y. van de Ven ◽  
Niculae Mincu ◽  
Jean Brunette ◽  
Guobin Ma ◽  
Mario Khayat ◽  
...  

2020 ◽  
Vol 4 (5) ◽  
pp. 473-483 ◽  
Author(s):  
Glyn Jones ◽  
Adam Kleczkowski

Plant health is relatively poorly funded compared with animal and human health issues. However, we contend it is at least as complex and likely more so given the number of pests and hosts and that outbreaks occur in poorly monitored open systems. Modelling is often suggested as a method to better consider the threats to plant health to aid resource and time poor decision makers in their prioritisation of responses. However, like other areas of science, the modelling community has not always provided accessible and relevant solutions. We describe some potential solutions to developing plant health models in conjunction with decision makers based upon a recent example and illustrate how an increased emphasis on plant health is slowly expanding the potential role of modelling in decision making. We place the research in the Credibility, Relevance and Legitimacy (CRELE) framework and discuss the implications for future developments in co-construction of policy-linked models.


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