Risk of congenital abnormalities in children born to women with ulcerative colitis: a population-based, case-control study

2003 ◽  
Vol 98 (9) ◽  
pp. 2006-2010 ◽  
Author(s):  
Bente Norgard ◽  
Erzsebet Puho ◽  
Lars Pedersen ◽  
Andrew E. Czeizel ◽  
Henrik T. Sorensen
Keyword(s):  
Ulcerative Colitis ◽  
Case Control Study ◽  
Congenital Abnormalities ◽  
Population Based ◽  
Case Control ◽  
Control Study

A Population-Based Case-Control Study on the Effect of Bronchial Asthma During Pregnancy for Congenital Abnormalities of the Offspring

2006 ◽  
Vol 43 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Lilla Tamási ◽  
Ákos Somoskövi ◽  
Veronika Müller ◽  
Zoltán Bártfai ◽  
Nándor Ács ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Case Control Study ◽  
Congenital Abnormalities ◽  
Population Based ◽  
Case Control ◽  
Control Study

Maternal panic disorder and congenital abnormalities: A population-based case-control study

2006 ◽  
Vol 76 (4) ◽  
pp. 253-261 ◽  
Author(s):  
Nándor ács ◽  
Ferenc Bánhidy ◽  
Erzsébet Horváth-Puhó ◽  
Andrew E. Czeizel
Keyword(s):  
Panic Disorder ◽  
Case Control Study ◽  
Congenital Abnormalities ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Estimating the Risk of Ulcerative Colitis-Associated Pyoderma Gangrenosum: A Population-Based Case-Control Study

2020 ◽  
Author(s):  
Khalaf Kridin ◽  
Giovanni Damiani ◽  
Ralf J Ludwig ◽  
Dana Tzur Bitan ◽  
Arnon D. Cohen
Keyword(s):  
Ulcerative Colitis ◽  
Pyoderma Gangrenosum ◽  
Case Control Study ◽  
Statistical Significance ◽  
Subsequent Development ◽  
Fold Increase ◽  
Population Based ◽  
Case Control ◽  
Control Subjects ◽  
Control Study

Abstract BackgroundUlcerative colitis (UC) is a well-known underlying comorbidity in pyoderma gangrenosum (PG). However, the relative risk conferred by UC for the subsequent development of PG is yet to be explicated.ObjectiveTo estimate the magnitude of the association between UC and the subsequent occurrence of PG, thus enabling to assess the PG risk with UC.MethodsA population-based case-control study was conducted comparing PG patients (n = 302) with age-, sex- and ethnicity-matched control subjects (n = 1,497) regarding the presence of UC. Logistic regression models were utilized for univariate and multivariate analyses.ResultsThe prevalence of UC was greater in patients with PG than in control subjects (7.3% vs. 0.5%, respectively; P < 0.001). A 15-fold increase in the odds of PG with UC (OR, 14.62 95% CI, 6.45–33.18) was observed. This association retained its statistical significance following a sensitivity analysis excluding UC cases diagnosed up to 2 years prior to PG (OR, 9.88; 95% CI, 3.91–24.97), and after adjusting for confounding factors (adjusted OR, 10.78; 95% CI, 4.55–25.52). The median latency between the diagnosis of UC and the development of PG was 4.59 years. Patients with both PG and UC were younger and had a lower prevalence of smoking when compared to the remaining patients with PG.ConclusionsUC increases the odds of developing PG by 15-folds. Physicians managing patients with UC should be aware of this increased burden. Patients with UC may be advised to avoid additional precipitating factors of PG.

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