Anticardiolipin antibodies, a disease marker for ischemic cerebrovascular events in a younger patient population?

1992 ◽  
Vol 86 (3) ◽  
pp. 304-307 ◽  
Author(s):  
A. Czlonkowska ◽  
M. Meurer ◽  
W. Palasik ◽  
M. Baranska-Gieruszczak ◽  
T. Mendel ◽  
...  
Keyword(s):  
Patient Population ◽  
Anticardiolipin Antibodies ◽  
Disease Marker ◽  
Cerebrovascular Events ◽  
Younger Patient

scholarly journals Clinical, neurovascular and neuropathological features in sneddon's syndrome

2007 ◽  
Vol 65 (2b) ◽  
pp. 390-395 ◽  
Author(s):  
Jaqueline Luvisotto Marinho ◽  
Élcio Juliato Piovesan ◽  
Moacir Pereira Leite Neto ◽  
Luiz Roberto Kotze ◽  
Lúcia de Noronha ◽  
...  
Keyword(s):  
Young Women ◽  
Renal Involvement ◽  
Cerebral Atrophy ◽  
Anticardiolipin Antibodies ◽  
Livedo Reticularis ◽  
Sneddon's Syndrome ◽  
Sneddon’S Syndrome ◽  
Cerebrovascular Events ◽  
History Of ◽  
Ct And Mri

Sneddon's syndrome (SS) is characterized by ischemic cerebrovascular episodes and livedo reticularis. It is more common in young women and can also be associated with valvulopathy, a history of spontaneous abortion, renal involvement and vascular dementia. We describe three cases of young women with this disease. The patients had repeated ischemic cerebral episodes, livedo reticularis and thrombocytopenia. CT and MRI showed strokes and cerebral atrophy. Autopsy in one of the patients revealed cerebral infarctions. Anticardiolipin antibodies were detected in two patients. Antiphospholipid antibodies may be found in some patients with ischemic cerebrovascular events and livedo reticularis. SS may thus be associated with antiphospholipid syndrome. We described three new cases of SS and discuss the pathophysiology of this disease.

Pancreatic adenocarcinoma (PAC) in a younger patient population: 10-year experience at Memorial Sloan-Kettering Cancer Center (MSKCC)

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 4623-4623
Author(s):  
A. Duffy ◽  
M. Capanu ◽  
P. Allen ◽  
R. Kurtz ◽  
E. Ludwig ◽  
...  
Keyword(s):  
Pancreatic Adenocarcinoma ◽  
Patient Population ◽  
Cancer Center ◽  
Younger Patient

Evaluation of Bronchoscopic-Assisted Percutaneous Tracheostomy

2006 ◽  
Vol 72 (10) ◽  
pp. 970-972 ◽  
Author(s):  
Jason P. Tomsic ◽  
Mark C. Connolly ◽  
Victor C. Joe ◽  
David T. Wong
Keyword(s):  
Performance Improvement ◽  
Patient Population ◽  
Percutaneous Tracheostomy ◽  
Improvement Project ◽  
Study Objective ◽  
Potential Problems ◽  
Younger Patient ◽  
Free Placement ◽  
A Performance

The convenience of bedside percutaneous tracheostomy (PT) is growing in popularity. Some centers are placing PTs without the assistance of bronchoscopy. The study objective was to identify operative and perioperative problems with PT placement and to identify potential problems with bronchoscopy-free placement. All operative and perioperative events were prospectively recorded as a performance improvement project at our institution while performing bronchoscopic-assisted bedside PTs. One hundred eighty-three patients underwent PT placement, all with the assistance of a bronchoscope. Although most PT was performed without incident, some of the complications can be severe. The majority of difficulties can be prevented with bronchoscopic assistance. An unexpected procedural difficulty that has not been previously reported is the dilatational difficulty in the younger patient population. Some of these patients required an additional tracheal incision with a scalpel. This may be from a healthy pretracheal fascia and/or musculature.

scholarly journals Anticardiolipin antibodies in ischaemic heart disease: marker or myth?

Heart ◽  
1993 ◽  
Vol 69 (5) ◽  
pp. 391-394 ◽  
Author(s):  
K V Phadke ◽  
R A Phillips ◽  
D T Clarke ◽  
M Jones ◽  
P Naish ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Anticardiolipin Antibodies ◽  
Disease Marker

Association of partial nephrectomy with a long-term survival advantage in patients between age 20 and 44 with renal cell carcinomas ≤ 4 cm: An analysis of the SEER database.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 408-408
Author(s):  
Michael R. Daugherty ◽  
Gennady Bratslavsky
Keyword(s):  
Overall Survival ◽  
Selection Bias ◽  
Renal Cell ◽  
Patient Population ◽  
Collecting Duct ◽  
Survival Advantage ◽  
Term Survival ◽  
Younger Patient ◽  
Chi Square Analysis

408 Background: PN decreases the risk of developing chronic kidney disease as opposed to RN. While prior studies have demonstrated the survival advantage of PN in older patients, they have been criticized by selection bias in procedure selection due to comorbidities. We hypothesized that the long-standing effects of renal preservation would manifest in a survival advantage of a younger patient population, where this selection bias is minimized. Methods: The SEER 18-registries database was queried for patients between the ages of 20 to 44 that were surgically treated with either PN or RN for RCC between 1993 and 2003. We have excluded patients with metastatic or locally advanced disease and included patients with localized tumors ≤4 cm with known grade. The histologies selected were clear cell, papillary, chromophobe, sarcomatoid, collecting duct, and renal cell. The final cohort consisted of 222 and 494 subjects treated with PN and RN respectively. Chi-square analysis compared tumor variables and patient characteristics. Cancer-specific and overall survival rates were compared at 5 and 10 years using Kaplan-Meier analyses. Results: There were no differences between patients treated by PN or RN in demographics or tumor characteristics. Additionally, there was no difference in cancer-specific survival between the two groups at 5 or 10 years (p= 0.34 and p = 0.1 respectively). While there was no difference in 5-year overall survival (98.2% vs. 95.5%, p = 0.07), the patients treated with PN had an advantage in 10-year overall survival compared to patients treated with RN (94% vs. 89.7%, p = 0.025). Conclusions: Present SEER analyses demonstrate that when compared to RN, PN results in improved overall survival in patients treated for small, localized RCC. As expected, the survival advantage is observed late and supports the importance of long-term renal functional preservation. The present study of a younger patient population allows for minimizing selection bias in choosing surgical procedure due to comorbidities and provides further support for maximal renal preservation in patients with a life expectancy of 10 years or more.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

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