Dental erosion and salivary flow rate in cerebral palsy individuals with gastroesophageal reflux

Background: The dental needs of cerebral palsy children are an area of study much in need of attention. The neglect of this aspect should be rectified, and simpler diagnostic methodologies should be established and used to serve this purpose. Aim: This study aimed to determine oral health status and salivary biomarkers (salivary flow rate, pH, buffering capacity) among children with cerebral palsy (CP), to compare their data with that of their healthy siblings, and to evaluate the relationship between salivary biomarkers and dental caries. Methods: A total of 30 CP children (study group) and 30 normal healthy siblings (controls) were selected between the ages of 5 and 12 years. Salivary biomarkers were assessed, and oral health status was examined. Statistical Analysis: Chi-square test was used for comparison of oral health status. “Unpaired t test was used to compare caries indexes (decay/filled teeth–primary dentition [dft] and decay/missing/filled teeth–permanent dentition [DMFT]) and salivary biomarkers between the groups. Pearson correlation was used to find the correlation between salivary biomarkers and caries. Results: The dft scores were significantly higher in the study group (P<0.05). The pH values and salivary flow rates were significantly lower in the study group (P<0.05 and P<0.001, respectively). There was a significant correlation between DMFT scores and salivary flow rate in the study group (P<0.05). Conclusion: Low pH and low salivary flow rate might be risk factors for dental caries in CP populations; moreover, the significant correlation between DMFT score and salivary flow rate suggests that salivary flow rate could be used as a screening tool for assessing at-risk subjects in such populations.

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Botulinum toxin effect on salivary flow rate in children with cerebral palsy

Neurology ◽

10.1212/01.wnl.0000142040.57474.a6 ◽

2004 ◽

Vol 63 (8) ◽

pp. 1371-1375 ◽

Cited By ~ 58

Author(s):

P. H. Jongerius ◽

J. J. Rotteveel ◽

J. van Limbeek ◽

F. J.M. Gabreels ◽

K. van Hulst ◽

...

Keyword(s):

Cerebral Palsy ◽

Botulinum Toxin ◽

Flow Rate ◽

Salivary Flow ◽

Salivary Flow Rate ◽

Children With Cerebral Palsy

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Exploring Some Aspects Associated with Dentine Hypersensitivity in Children

The Scientific World JOURNAL ◽

10.1155/2015/764905 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Caleb Shitsuka ◽

Fausto Medeiros Mendes ◽

Maria Salete Nahás Pires Corrêa ◽

Mariana Ferreira Leite

Keyword(s):

Flow Rate ◽

Oral Hygiene ◽

Dietary Habits ◽

Bitter Taste ◽

Salivary Flow ◽

Dental Erosion ◽

Salivary Flow Rate ◽

Dentine Hypersensitivity ◽

Dental Biofilm ◽

Whole Saliva

Background. The etiology of dentine hypersensitivity (DH) is still inconclusive and there are few studies concerning it in children.Aim. To evaluate clinical, dietary, and salivary variables in children with DH complaints.Design. Forty-eight children were asked about DH. Data regarding dietary habits were collected from the children’s parents and an examination was performed to determine dental erosion. Dental biofilm was estimated by oral hygiene status, according to Greene and Vermillion’s Simplified Oral Hygiene Index (OHI-S). Whole saliva was collected under mechanical stimulation and evaluated salivary flow rate, initial pH, buffer capacity, and calcium and phosphate concentrations. The temperature of soft drinks, drinking method, sense of bitter taste, and other variables were also determined. Possible factors associated with DH were analyzed by univariate and multiple Poisson regression analyses. The prevalence ratio (PR) values and 95% confidence intervals (95% CI) were calculated.Results. DH was associated with the presence of dental erosion (PR; 95% CI = 2.23; 1.05 to 4.71) and salivary flow rate (2.49; 1.05 to 5.91). When the presence of erosion was not included, other variables were retained as follows: bitter taste (2.36; 1.38 to 4.03), OHI-S (0.47; 0.23 to 0.97).Conclusion. DH in children is associated with factors related to dental erosion.

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The Role of Saliva in Dental Erosion and a Prosthetic Approach to Treatment: A Case Report

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-10-3-74 ◽

2009 ◽

Vol 10 (3) ◽

pp. 74-80 ◽

Cited By ~ 3

Author(s):

Andac Barkin Bavbek ◽

Orhan Murat Dogan ◽

Tamer Yilmaz ◽

Arife Dogan

Keyword(s):

Case Report ◽

Flow Rate ◽

Composite Resin ◽

Salivary Flow ◽

Dental Erosion ◽

Buffering Capacity ◽

Composite Resins ◽

Salivary Flow Rate ◽

Oral Environment

Abstract Aim The aim of this report is to describe the relationship of some salivary parameters to dental erosion resulting from excessive citric acid consumption and present a description of a prosthetic approach used to restore the damaged dentition of a patient with severe erosion. Background The high consumption of dietary sources of acids can lead to erosion or the excessive wear of dental hard tissues. Erosion may be modified by salivary parameters such as flow rate, pH, and buffering capacity. Porcelain-fused-to-metal (PFM) restorations and composite resin veneers can be used successfully to restore impaired esthetics and eliminate tooth hypersensitivity in such cases. Results A 37-year-old woman with a history of excessive lemon consumption presented with a complaint of tooth hypersensitivity and the poor appearance of her dentition due to erosion. Stimulated and unstimulated salivary samples of the patient were evaluated for flow rate, pH, and buffering capacity before and after treatment. The pre-treatment values were found to be higher than post-treatment values. Stimulated samples showed an increase of salivary flow rate, pH, and buffering capacity. The measured parameters put forth the defensive potential of saliva against the acidic diet, and the salivary flow rate and buffering capacity decreased after reducing acidic consumption. The excessively eroded teeth were restored using PFM restorations whereas the superficially eroded teeth were restored with composite resins. Summary The introduction of acidic foods, beverages, or other agents can exceed the natural buffering capacity of saliva. The result is a lowering of the pH of the oral environment which can lead to erosion of enamel and dentin. Loss of tooth structure due to erosion can compromise the esthetics of the dentition and lead to hypersensitivity of the teeth. Teeth damaged by erosion can be successfully restored by composite resin or porcelain restorations and esthetics and function of dentition can be improved. Clinical Significance This report is a profound example of how the over consumption of acidic agents affect not only dental tissues but also the chemical balance of the oral environment as well as the oral habitat. Citation Bavbek AB, Dogan OM, Yilmaz T, Dogan A. The Role of Saliva in Dental Erosion and a Prosthetic Approach to Treatment: A Case Report. J Contemp Dent Pract 2009 May; (10)3:074-080.

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Acute Salivary Flow Rate Response to Transcutaneous Electrical Nerve Stimulation Versus Electro-acupuncture

Case Medical Research ◽

10.31525/ct1-nct04211324 ◽

2019 ◽

Author(s):

Keyword(s):

Flow Rate ◽

Nerve Stimulation ◽

Transcutaneous Electrical Nerve Stimulation ◽

Salivary Flow ◽

Salivary Flow Rate ◽

Electrical Nerve Stimulation

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Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

BMC Oral Health ◽

10.1186/s12903-021-01471-w ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

S. Bielfeldt ◽

D. Wilhelm ◽

C. Neumeister ◽

U. Schwantes ◽

K. -P. Wilhelm

Keyword(s):

Surface Tension ◽

Flow Rate ◽

Gum Arabic ◽

Salivary Flow ◽

Salivary Flow Rate ◽

Dry Mouth ◽

Main Ingredient ◽

Control Product ◽

Swallowing Problems ◽

The Mean

Abstract Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia. Chewing gum and sucking pastilles may relieve symptoms of xerostomia by increasing the salivary flow rate due to the mechanical effect of sucking and gustatory stimulation. Swallowing problems and the urge to cough or experiencing a tickling sensation in the throat might be alleviated through a reduction in dry mouth symptoms. We investigated whether a pastille containing four polysaccharides increased the salivary flow rate and relieved the symptoms of dry mouth. Methods Participating subjects with xerostomia were randomized into two equally balanced treatment groups. Subjects received the pastille on Day 1 and a control product (Parafilm®) on Day 3, or vice versa. Unstimulated saliva was collected every 2.5 min for 0–10 min. Stimulated saliva was collected after subjects sucked the pastille or the control product. The salivary flow rate was determined gravimetrically, and, in parallel, the feeling of dry mouth was assessed using a visual analog scale. Saliva surface tension was measured in pooled saliva samples (0–5 min of sampling). Additionally, in stimulated saliva from six subjects who sucked the pastille, the presence of the main ingredient—gum arabic—was examined by Raman spectroscopy. Results Chewing the pastille significantly increased the mean salivary flow rate by 8.03 g/10 min compared to the mean changes after chewing the control product (+ 3.71 g/10 min; p < 0.0001). The mean score of dry mouth was significantly alleviated by the pastille (− 19.9 ± 17.9 mm) compared to the control product (− 3.3 ± 18.1 mm). No difference between the two products was seen regarding the saliva surface tension. Gum arabic was present in the saliva of all investigated subjects for up to 10 min after sucking the pastille. Conclusions The pastille was well tolerated and effective in increasing the salivary flow rate and reducing mouth dryness after sucking. These results were in line with the detection of the main ingredient, gum arabic, in saliva for up to 10 min after sucking the pastille. Trial registration German Register Clinical Trials (Deutsches Register Klinische Studien, DRKS) DRKS-ID: DRKS00017393, Registered 29 May 2019, https://www.drks.de/drks_web/navigate.do?navigationId=trial. HTML&TRIAL_ID = DRKS00017393.

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Salivary flow rate and the risk of cognitive impairment among Korean elders: a cross-sectional study

BMC Geriatrics ◽

10.1186/s12877-021-02200-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Minh-Tung Do ◽

Huong Vu ◽

Jong-Koo Lee ◽

Sang-Min Park ◽

Joung-Sik Son ◽

...

Keyword(s):

Cognitive Impairment ◽

Flow Rate ◽

Salivary Flow ◽

Cross Sectional Study ◽

Community Dwelling ◽

Salivary Flow Rate ◽

Multivariable Logistic Regression Analysis ◽

Sectional Study ◽

Cross Sectional ◽

Denture Status

Abstract Background Salivary function has been suggested to be associated with cognitive impairment. However, the effect of salivary flow rate (SFR) on cognitive impairment remains unclear. This study aimed to investigate whether SFR is associated with cognitive impairment among Korean elders. Methods This cross-sectional study included 649 elders aged 65 and older in the Korean community-dwelling population. Cognitive impairment was assessed using the Mini-Mental Status Examination. Unstimulated SFR was measured and dichotomized. Denture status, age, sex, education level, smoking, drinking, diabetes, hypertension, and obesity were considered confounders. Multivariable logistic regression analysis was applied to assess the adjusted association. Stratified analysis by sex and denture status was performed to clarify the effect modification. Results Participants without cognitive impairment showed a higher SFR level than those with cognitive impairment (0.81 mL/min for non-cognitive impairment versus 0.52 mL/min for cognitive impairment, p < 0.001). After controlling for confounders, participants with low SFR (< 0.3 mL/min) were more likely to have cognitive impairment by 1.5 times than participants with normal SFR (odds ratio [OR] = 1.5, confidence interval [CI] = 1.05–2.10). The association of low SFR with cognitive impairment was higher in women and dentate participants: about 10% higher in women (OR = 1.63, CI = 1.07–2.50) and about 22% higher in dentate participants (OR = 1.82, CI = 1.41–2.90). Conclusions Salivary flow rate is independently associated with cognitive impairment among Korean elders. The association was modified in females and dentate elders. Physicians and dentists should consider low SFR and cognitive impairment as a risk factor between them in clinics.

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