The healing power of well-being

2011 ◽  
Vol 23 (4) ◽  
pp. 145-155 ◽  
Author(s):  
Jobin Mathew ◽  
Cheramadathikudyl Scariya Paulose

Neuroendocrine system plays an important role in modulating our body functions and emotions. At the same time, emotions implicate a pivotal role in the regulation of brain function and neuroendocrine system. Negative affective states such as depression and stress are associated with premature mortality and increase the risk of various fatal diseases. It has been suggested that positive affective states are protective and improve our health and productiveness. Several potential mechanisms have been posited to account for these associations including improved health behaviour, direct physiological benefits, enhanced resistance and recovery from stress among individuals with high versus low positive emotional resources. This review summarises information concerning the neuronal and hormonal systems in mood, impact of negative and positive affective states on the level of cortisol, epinephrine, serotonin, dopamine and endorphins. The functional correlation of neuronal and hormonal systems in the development of diseases and their ability to enhance health-relevant biological processes are also evaluated.

2021 ◽  
Vol 11 ◽  
Author(s):  
Dara Mojtahedi ◽  
Neil Dagnall ◽  
Andrew Denovan ◽  
Peter Clough ◽  
Sophie Hull ◽  
...  

Concerns toward public well-being and mental health are increasing considering the COVID-19 pandemic's global societal and individual impact. The present study builds on the current body of COVID-19 literature by examining the role of mental toughness (MT) in predicting negative affective states (depression, anxiety and stress) during the pandemic. The study also examined the effects of changes in employment on mental health and MT. Participants (N = 723) completed a battery of questionnaires including the Mental Toughness Questionnaire 48-item, The State-Trait Anxiety Inventory, and the Depression, Anxiety and Stress Scale – 21 items. Participants reported relatively higher levels of depression, stress and anxiety in comparison to pre-COVID-19 samples from previous research, with respondents who had lost their jobs during the pandemic reporting higher levels of negative affective states. Despite this, mentally tough individuals appeared to report lower levels of depression, anxiety and stress. Moreover, moderation analyses identified some interaction between MT and employment status when predicting depression, anxiety and stress. Our findings suggest that MT may have some utility in reducing the adverse mental health effects of the pandemic on individuals, however, further longitudinal research is needed to support these implications.


2016 ◽  
Vol 51 (1) ◽  
pp. 36-43 ◽  
Author(s):  
Magda J Castelhano-Carlos ◽  
Vera Baumans ◽  
Nuno Sousa

The use of animals is essential in biomedical research. The laboratory environment where the animals are housed has a major impact on them throughout their lives and influences the outcome of animal experiments. Therefore, there has been an increased effort in the refinement of laboratory housing conditions which is explicitly reflected in international regulations and recommendations. Since housing conditions affect behaviour and brain function as well as well-being, the validation of an animal model or paradigm to study the brain and central nervous system disorders is not complete without an evaluation of its implication on animal welfare. Here we discuss several aspects of animal welfare, comparing groups of six rats living in the PhenoWorld (PhW), a recently developed and validated paradigm for studying rodent behaviour, with standard-housed animals (in cages of six rats or pair-housed). In this study we present new data on home-cage behaviour showing that PhW animals have a clearer circadian pattern of sleep and social interaction. We conclude that, by promoting good basic health and functioning, together with the performance of natural behaviours, and maintaining animals’ control over some of their environment but still keeping some physical and social challenges, the PhW stimulates positive affective states and higher motivation in rats, which might contribute to an increased welfare for animals living in the PhW.


1992 ◽  
Vol 22 (1) ◽  
pp. 231-238 ◽  
Author(s):  
Ann D. Futterman ◽  
Margaret E. Kemeny ◽  
David Shapiro ◽  
William Polonsky ◽  
John L. Fahey

SYNOPSISFunctional and phenotypic immunological parameters were examined immediately before, after, and 30 minutes after experimentally-induced short-term positive (happiness) and negative (anxiety, depression) affective states and a neutral state, in five healthy subjects. Results indicated that all affective states induced more immune fluctuations (regardless of the direction) than the neutral state. Furthermore, among the affective states, anxiety induced the most immunological variability and depression the least.


Author(s):  
Nicolas Massaly ◽  
Tamara Markovic ◽  
Meaghan Creed ◽  
Ream Al-Hasani ◽  
Catherine M. Cahill ◽  
...  

2018 ◽  
Vol 115 (43) ◽  
pp. E10013-E10021 ◽  
Author(s):  
Chaona Chen ◽  
Carlos Crivelli ◽  
Oliver G. B. Garrod ◽  
Philippe G. Schyns ◽  
José-Miguel Fernández-Dols ◽  
...  

Real-world studies show that the facial expressions produced during pain and orgasm—two different and intense affective experiences—are virtually indistinguishable. However, this finding is counterintuitive, because facial expressions are widely considered to be a powerful tool for social interaction. Consequently, debate continues as to whether the facial expressions of these extreme positive and negative affective states serve a communicative function. Here, we address this debate from a novel angle by modeling the mental representations of dynamic facial expressions of pain and orgasm in 40 observers in each of two cultures (Western, East Asian) using a data-driven method. Using a complementary approach of machine learning, an information-theoretic analysis, and a human perceptual discrimination task, we show that mental representations of pain and orgasm are physically and perceptually distinct in each culture. Cross-cultural comparisons also revealed that pain is represented by similar face movements across cultures, whereas orgasm showed distinct cultural accents. Together, our data show that mental representations of the facial expressions of pain and orgasm are distinct, which questions their nondiagnosticity and instead suggests they could be used for communicative purposes. Our results also highlight the potential role of cultural and perceptual factors in shaping the mental representation of these facial expressions. We discuss new research directions to further explore their relationship to the production of facial expressions.


Author(s):  
Daniela Villani ◽  
Pietro Cipresso ◽  
Andrea Gaggioli ◽  
Giuseppe Riva

The emerging convergence of new technologies and health care is offering a new approach to support effective interventions. This chapter aims to describe how Positive Technology can help people cope with stress in several contexts. On the one hand, the potential capacity of sensor technologies to offer individuals the technology with which to monitor certain biological signals known to be associated with stress might serve to promote engagement with a mediated experience for stress management. On the other hand, the chapter focuses on the hedonic and eudaimonic experiences supported by technology in terms of inducing positive affective states and supporting personal growth by teaching strategies to reduce stress and enhance well-being. To further connect mediated experiences with real ones, the Interreality approach (IR) allows for the combination of assessment and intervention as inseparable parts of the general process of coping with stress.


2018 ◽  
Vol 94 (1114) ◽  
pp. 446-452 ◽  
Author(s):  
Borros M Arneth

BackgroundThe gut–brain axis facilitates a critical bidirectional link and communication between the brain and the gut. Recent studies have highlighted the significance of interactions in the gut–brain axis, with a particular focus on intestinal functions, the nervous system and the brain. Furthermore, researchers have examined the effects of the gut microbiome on mental health and psychiatric well-being.The present study reviewed published evidence to explore the concept of the gut–brain axis.AimsThis systematic review investigated the relationship between human brain function and the gut–brain axis.MethodsTo achieve these objectives, peer-reviewed articles on the gut–brain axis were identified in various electronic databases, including PubMed, MEDLINE, CIHAHL, Web of Science and PsycINFO.ResultsData obtained from previous studies showed that the gut–brain axis links various peripheral intestinal functions to brain centres through a broad range of processes and pathways, such as endocrine signalling and immune system activation. Researchers have found that the vagus nerve drives bidirectional communication between the various systems in the gut–brain axis. In humans, the signals are transmitted from the liminal environment to the central nervous system.ConclusionsThe communication that occurs in the gut–brain axis can alter brain function and trigger various psychiatric conditions, such as schizophrenia and depression. Thus, elucidation of the gut–brain axis is critical for the management of certain psychiatric and mental disorders.


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