A GENETIC STUDY OF INDUCIBLE ERYTHROMYCIN RESISTANCE IN STAPHYLOCOCCUS AUREUS

2009 ◽  
Vol 81B (5) ◽  
pp. 497-507
Author(s):  
Kathrine Dornbusch ◽  
Anna Dahlström
Keyword(s):  
Staphylococcus Aureus ◽  
Genetic Study ◽  
Erythromycin Resistance

Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220

Gene ◽  
1996 ◽  
Vol 183 (1-2) ◽  
pp. 143-148 ◽  
Author(s):  
Jeremy I. Ross ◽  
E.Anne Eady ◽  
Jonathan H. Cove ◽  
Simon Baumberg
Keyword(s):  
Staphylococcus Aureus ◽  
Functional System ◽  
Erythromycin Resistance

scholarly journals STAPHYLOCOCCUS AUREUS IN NURSING PROFESSIONALS AND THE MICROORGANISM’S SUSCEPTIBILITY PROFILE TO ANTIMICROBIALS

2017 ◽  
Vol 26 (2) ◽  
Author(s):  
Letícia Pimenta Lopes ◽  
Daiana Patrícia Marchetti Pio ◽  
Lílian Andreia Fleck Reinato ◽  
Gilberto Gambero Gaspar ◽  
Marinésia Aparecida do Prado ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cross Sectional Study ◽  
Carrier State ◽  
Nasal Secretion ◽  
Penicillin Resistance ◽  
Erythromycin Resistance ◽  
Cross Sectional ◽  
Oxacillin Resistance ◽  
Nursing Professionals ◽  
And Control

ABSTRACT Objective: to identify the carrier’s state and the susceptibility profile of Staphylococcus aureus isolated from saliva and nasal secretion of nursing professionals to antibiotics. Method: cross-sectional study that used saliva and nasal secretion samples of 100 nursing professionals who provide care for patients with HIV/Aids. Results: forty-three percent of the participants presented positive saliva or nasal secretion samples for Staphylococcus aureus. Of the 74 nasal secretion samples with Staphylococcus aureus, 14.9% presented oxacillin resistance; 91.9% presented penicillin resistance; 44.6% presented erythromycin resistance, and 41.9% presented clindamycin resistance. Of the 12 positive saliva samples, 16.7% presented oxacillin resistance; 100.0% presented penicillin resistance; 33.4% presented erythromycin resistance, and 25.0% presented clindamycin resistance. Conclusion: nursing professionals, once aware of their carrier state of multi-resistant microorganisms, will supervise their care practices and more efficiently adopt measures for prevention and control of the epidemiological chain of these bacteria in their work environment.

scholarly journals A Novel Erythromycin Resistance Methylase Gene (ermTR) in Streptococcus pyogenes

1998 ◽  
Vol 42 (2) ◽  
pp. 257-262 ◽  
Author(s):  
Helena Seppälä ◽  
Mikael Skurnik ◽  
Hanna Soini ◽  
Marilyn C. Roberts ◽  
Pentti Huovinen
Keyword(s):  
Staphylococcus Aureus ◽  
Nucleotide Sequence ◽  
Streptococcus Pyogenes ◽  
Resistance Genes ◽  
Target Site ◽  
Clinical Strain ◽  
Erythromycin Resistance ◽  
Coagulase Negative Staphylococci ◽  
Methylase Gene

ABSTRACT Erythromycin resistance among streptococci is commonly due to target site modification by an rRNA-methylating enzyme, which results in coresistance to macrolide, lincosamide, and streptogramin B antibiotics (MLSB resistance). Genes belonging to theermAM (ermB) gene class are the only erythromycin resistance methylase (erm) genes inStreptococcus pyogenes with MLSB resistance that have been sequenced so far. We identified a novelerm gene, designated ermTR, from an erythromycin-resistant clinical strain of S. pyogenes(strain A200) with an inducible type of MLSBresistance. The nucleotide sequence of ermTR is 82.5% identical to ermA, previously found, for example, in Staphylococcus aureus and coagulase-negative staphylococci. Our finding provides the first sequence of anerm gene other than ermAM that mediates MLSB resistance in S. pyogenes.

scholarly journals Constitutive Erythromycin Resistance Plasmid in Staphylococcus aureus

Microbiology ◽  
1980 ◽  
Vol 121 (2) ◽  
pp. 513-516 ◽  
Author(s):  
M. C. F. BASTOS ◽  
M. C. BONALDO ◽  
E. G. C. PENIDO
Keyword(s):  
Staphylococcus Aureus ◽  
Erythromycin Resistance ◽  
Resistance Plasmid

scholarly journals Prevalence and determinants of nasal colonization with antibiotic-resistant Staphylococcus aureus among unselected patients attending general practitioners in Germany

2004 ◽  
Vol 132 (4) ◽  
pp. 655-662 ◽  
Author(s):  
S. LIETZAU ◽  
T. STÜRMER ◽  
A. ERB ◽  
H. VON BAUM ◽  
R. MARRE ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
General Practitioners ◽  
Great Majority ◽  
Antibiotic Use ◽  
Penicillin G ◽  
Erythromycin Resistance ◽  
Antibiotic Resistant ◽  
Minimal Inhibitory Concentrations ◽  
High Prevalence ◽  
Nasal Swabs

Although the great majority of antibiotics are prescribed outside hospitals, little is known about the prevalence and determinants of antibiotic resistance in the group of outpatients. Nasal swabs were taken from 627 consecutive patients aged 40 years or above attending general practitioners in Southern Germany. Staphylococcus aureus was cultured and minimal inhibitory concentrations to various antibiotics were tested. Nasal swabs of 152 patients were positive for S. aureus. Prevalence of resistance was 68·3, 8·3 and 0·7% for penicillin G, erythromycin, and oxacillin respectively. Antibiotic use within the last month was associated with erythromycin resistance [adjusted odds ratio (OR) 7·4; 95% confidence interval (CI) 1·0–53]. Besides a high prevalence of resistance to penicillinase-instable antibiotics we found only one (0·7%) methicillin-resistant S. aureus. Recent antibiotic use was associated with increased resistance to erythromycin.

scholarly journals Induction of Erythromycin Resistance in Staphylococcus aureus by Erythromycin Derivatives

1976 ◽  
Vol 9 (1) ◽  
pp. 128-130 ◽  
Author(s):  
S. Pestka ◽  
R. Vince ◽  
R. LeMahieu ◽  
F. Weiss ◽  
L. Fern ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Erythromycin Resistance
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