Common laboratory tests, values, and interpretations

1985 ◽  
Vol 5 (6) ◽  
pp. 264-269 ◽  
Author(s):  
ALFREDO J. FERNANDEZ ◽  
NORMAN A. FLAXMAN
1981 ◽  
Vol 46 (04) ◽  
pp. 752-756 ◽  
Author(s):  
L Zuckerman ◽  
E Cohen ◽  
J P Vagher ◽  
E Woodward ◽  
J A Caprini

SummaryThrombelastography, although proven as a useful research tool has not been evaluated for its clinical utility against common coagulation laboratory tests. In this study we compare the thrombelastographic measurements with six common tests (the hematocrit, platelet count, fibrinogen, prothrombin time, activated thromboplastin time and fibrin split products). For such comparisons, two samples of subjects were selected, 141 normal volunteers and 121 patients with cancer. The data was subjected to various statistical techniques such as correlation, ANOVA, canonical and discriminant analysis to measure the extent of the correlations between the two sets of variables and their relative strength to detect blood clotting abnormalities. The results indicate that, although there is a strong relationship between the thrombelastographic variables and these common laboratory tests, the thrombelastographic variables contain additional information on the hemostatic process.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
D Vallone ◽  
A Tamburrano ◽  
C Carrozza ◽  
A Urbani ◽  
A Cambieri ◽  
...  

Abstract Computerized Clinical Decision Support Systems (CCDSS) are information technology-based systems that use specific patient characteristics and combine them with rule-based algorithms. The aim of this study is to conduct a survey to measure and assess the over-utilization rates of laboratory requests and to estimate the monthly cost of inappropriate requests in inpatients of the “Fondazione Policlinico Universitario A. Gemelli IRCCS” Care Units. This observational study is based on the count of rules violations for 43 different types of laboratory tests requested by the Hospital physicians, for a total of 5,716,370 requests, over a continuous period of 20 months (from 1 July 2016 to 28 February 2018). Requests from all the hospital internal departments (except for Emergency, Intensive Care Units and Urgent requests) were monitored. The software intercepted and counted, in silent mode for the operator, all requests and violations for each laboratory test among those identified. During the observation period a mean of 285,819 requests per month were analyzed and 40,462 violations were counted. The global rate of overuse was 15.2% ± 3.0%. The overall difference among sub-groups was significant (p < 0.001). The most inappropriate exams were Alpha Fetoprotein (85.8% ± 30.5%), Chlamydia trachomatis PCR (48.7% ± 8.8%) and Alkaline Phosphatase (20.3% ± 6.5%). All the exams, globally considered, generated an estimated avoidable cost of 1,719,337€ (85,967€ per month) for the hospital. This study reports rates (15.2%) similar to other works. The real impact of inappropriateness is difficult to assess, but the generated costs for patients, hospitals and health systems are certainly high and not negligible. Key messages It would be desirable for international medical communities to produce a complete panel of prescriptive rules for all the most common laboratory exam. That is useful not only to reduce costs, but also to ensure standardization and high-quality care.


2007 ◽  
Vol 40 (3) ◽  
pp. 261-269
Author(s):  
Sumiko Igarashi ◽  
Kiyoshi Ichihara ◽  
Masatoshi Takiya ◽  
Mitsuru Kurata ◽  
Takayasu Taira ◽  
...  

2011 ◽  
Vol 85 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Laurens Manning ◽  
Stephen P. Chubb ◽  
Peter M. Siba ◽  
Ivo Mueller ◽  
Timothy M. E. Davis ◽  
...  

2019 ◽  
Vol 34 (12) ◽  
pp. 2786-2795 ◽  
Author(s):  
Anshula Ambasta ◽  
Stefana Pancic ◽  
Brian M. Wong ◽  
Todd Lee ◽  
Deirdre McCaughey ◽  
...  

2003 ◽  
Vol 8 (1) ◽  
pp. 6-12
Author(s):  
Masashi TSUNODA ◽  
Humio TSUNODA ◽  
Lucille GUEVARRA ◽  
David J. TOLLERUD

2017 ◽  
Vol 41 (2) ◽  
Author(s):  
Maria Salinas ◽  
Maite Lopez-Garrigos ◽  
Emilio Flores ◽  
Carlos Leiva-Salinas

AbstractBackground:The aim was to study the regional variability in the request of the ten most frequently ordered laboratory tests in primary care in Spain.Methods:Spain is divided into autonomous communities (AACC), first level health care divisions. Every AACC is divided into health departments (HDs). A laboratory attends the needs of every HD inhabitant. Laboratories from different HDs participated in the study. They reported the request of the ten most commonly requested laboratory tests in primary care during the year 2014 according to prior evidence: alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol, creatinine, γ-glutamyl transpeptidase (GGT), glucose, HDL-cholesterol, triglycerides, uric acid and urinalysis. Test-utilization rates were calculated as tests per 1000 inhabitants. Laboratories were grouped in the different AACC and the results for each region were compared using the coefficient of quartile dispersion (CQD), calculated using the first (Q1) and third (Q3) quartiles for each data set, as follows: (Q3−Q1)/(Q3+Q1).Results:One hundred and ten laboratories participated, corresponding to 27,798,262 inhabitants (59.8% Spanish population) from 15 AACC. 82,710,869 tests were requested. AST, GGT and uric acid showed the greatest variation.Conclusions:There were significant regional differences in how the most common laboratory tests were ordered in Spain.


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