Heart Rate, Heart Rate Variability, and Arrhythmias in Dogs with Myxomatous Mitral Valve Disease

Cardiac diseases promote alterations in the autonomic control of the heart, leading to an increase in heart rate and, as a result, a decrease in heart rate variability (HRV).The aim of this study was to evaluate if the development of heart failure secondary to degenerative mitral valve disease (DMVD) concurs with changes in autonomic modulation of heart rhythm which are assessed by long electrocardiography examination (Holter). Dogs were evaluated by clinical examination and echocardiography in order to be categorized into the following groups: Control (healthy; n=6), DMVD (disease without heart failure; n=8), and DMVD heart failure (disease with heart failure; n=13). Arrhythmias and frequency domain HRV were determined by Holter. Diseased animals, when compared to healthy, had significantly lower total power, which indicates overall HRV. DMVD heart failure dogs also showed other disturbances such as high incidence of supraventricular arrhythmias, high heart rate, little amount of pauses (2.0s long between consecutive heartbeats), longer time in tachycardia, shorter time in bradycardia, low high frequency (parasympathetic control), and high low frequency (sympathetic and parasympathetic control) when compared to control (p<0.05). In DMVD dogs, Holter-derived variables changed with the development of heart failure.

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Heart rate variability parameters of myxomatous mitral valve disease in dogs with and without heart failure obtained using 24-hour Holter electrocardiography

Veterinary Record ◽

10.1136/vr.100202 ◽

2012 ◽

Vol 170 (24) ◽

pp. 622-622 ◽

Cited By ~ 16

Author(s):

M. S. Oliveira ◽

R. A. L. Muzzi ◽

R. B. Araújo ◽

L. A. L. Muzzi ◽

D. F. Ferreira ◽

...

Keyword(s):

Heart Failure ◽

Heart Rate ◽

Heart Rate Variability ◽

Mitral Valve ◽

Mitral Valve Disease ◽

Valve Disease

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Short-term heart rate variability in dogs with sick sinus syndrome or chronic mitral valve disease as compared to healthy controls

Polish Journal of Veterinary Sciences ◽

10.1515/pjvs-2017-0021 ◽

2017 ◽

Vol 20 (1) ◽

pp. 167-172 ◽

Cited By ~ 6

Author(s):

Sz. Bogucki ◽

A. Noszczyk-Nowak

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Standard Deviation ◽

Mitral Valve ◽

Mitral Valve Disease ◽

Sick Sinus Syndrome ◽

Study Groups ◽

Valve Disease ◽

Healthy Controls ◽

Short Term

Abstract Heart rate variability is an established risk factor for mortality in both healthy dogs and animals with heart failure. The aim of this study was to compare short-term heart rate variability (ST-HRV) parameters from 60-min electrocardiograms in dogs with sick sinus syndrome (SSS, n=20) or chronic mitral valve disease (CMVD, n=20) and healthy controls (n=50), and to verify the clinical application of ST-HRV analysis. The study groups differed significantly in terms of both time - and frequency- domain ST-HRV parameters. In the case of dogs with SSS and healthy controls, particularly evident differences pertained to HRV parameters linked directly to the variability of R-R intervals. Lower values of standard deviation of all R-R intervals (SDNN), standard deviation of the averaged R-R intervals for all 5-min segments (SDANN), mean of the standard deviations of all R-R intervals for all 5-min segments (SDNNI) and percentage of successive R-R intervals >50 ms (pNN50) corresponded to a decrease in parasympathetic regulation of heart rate in dogs with CMVD. These findings imply that ST-HRV may be useful for the identification of dogs with SSS and for detection of dysautonomia in animals with CMVD.

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Heart rate variability and quality of life in dogs with mitral valve disease treated with metoprolol

Brazilian Journal of Veterinary Medicine ◽

10.29374/2527-2179.bjvm003020 ◽

2021 ◽

Vol 43 ◽

pp. e003020

Author(s):

Tamyris Beluque ◽

Aparecido Antonio Camacho ◽

Roberto Navarrete Ampuero ◽

Jaislane Bastos Braz ◽

Murillo Daparé Kirnew ◽

...

Keyword(s):

Quality Of Life ◽

Heart Rate ◽

Heart Rate Variability ◽

Mitral Valve ◽

Mitral Valve Disease ◽

Valve Disease

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Assessment of heart rate turbulence in dogs with myxomatous mitral valve disease

Open Veterinary Journal ◽

10.5455/ovj.2021.v11.i4.13 ◽

2021 ◽

Vol 11 (4) ◽

pp. 635

Author(s):

Julio Santos ◽

Bruna Costa ◽

Stephany Lucina ◽

Karla Olaguivel ◽

Giovana Tulesky ◽

...

Keyword(s):

Heart Rate ◽

Mitral Valve ◽

Mitral Valve Disease ◽

Valve Disease ◽

Heart Rate Turbulence

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Vasovagal tonus index in dog with myxomatous mitral valve disease

Pesquisa Veterinária Brasileira ◽

10.1590/s0100-736x2017001000023 ◽

2017 ◽

Vol 37 (10) ◽

pp. 1181-1186 ◽

Cited By ~ 1

Author(s):

Bruna C. Brüler ◽

Amália T. Giannico ◽

Gustavo Dittrich ◽

Marlos G. Sousa

Keyword(s):

Internal Medicine ◽

Heart Failure ◽

Heart Rate ◽

Congestive Heart Failure ◽

Mitral Valve ◽

Cardiac Remodeling ◽

Mitral Valve Disease ◽

Valve Disease ◽

Rr Intervals ◽

Naturally Occurring

ABSTRACT: The vasovagal tonus index (VVTI) is a useful and assessable index, obtained from standard ECG recordings, that is used to estimate heart rate variability (HRV), and may provide valuable information regarding the likelihood of progression into congestive heart failure (CHF). In this paperwork, we investigated how the vasovagal tonus index (VVTI) behaves in dogs with naturally-occurring myxomatous mitral valve disease (MMVD) Electrocardiographic (ECG) recordings and echocardiographic data of 120 patients diagnosed with MMVD were reviewed. The VVTI was calculated from twenty consecutive RR intervals for each dog enrolled in the study. Lower VVTI values were found in MMVD patients in American College of Veterinary Internal Medicine (ACVIM) stage C compared with stages B1 and B2. Values were also lower in patients with severe cardiac remodeling. When a cut-off value of 6.66 is used, VVTI was able to discriminate MMVD patients in stage C from B1 and B2 dogs with a sensitivity of 70 per cent and a specificity of 77 per cent. MMVD dogs in which VVTI is lower than 6.66 are 30% more likely to develop congestive heart failure (CHF).

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